The Cell as a Unit of Health and Disease summary from Robbins & Cotran

The Cell as a Unit of Health and Disease

 The Genome
1. Non-coding DNA
a) Definition and classes of functional non-protein-coding sequences
b) DNA variation
2. Histone Organization
a) Epigenetic factors that cell type-specific differences
3. MicroRNA and Long Coding RNA

 Cellular House Keeping
1. Plasma Membrane: Protection and Nutrient Acquisition
2. Cytoskeleton and Cellular Interactions
a) Major classes of Cytoskeleton Proteins
b) Cellular Interaction: Cell Junctions
3. Biosynthetic Machinery: Endoplasmic Reticulum and Golgi
4. Waste Disposal: Lysosomes and Proteasomes

 Cellular Metabolism and Mitochondrial Function
1. Energy Generation
2. Intermediate Metabolism
3. Cell Death: Necrosis and Apoptosis

 Cellular Activation
1. Cell Signalling
2. Signalling Pathways
3. Receptors

 Signal Transduction Pathways
1. Receptors
2. Effects of protein phosphorylation
3. Transcription Factors

 Growth Factor and Receptors
1. Factors and their functions

 Interactions with the Extracellular Matrix
1. Functions of the ECM
2. Basic Forms
3. Components

 Maintaining Cell Populations
1. Proliferation and Cell Cycle

 Stem Cells
1. Characteristics
2. Varieties/Types
3. Regenerative Medicine