NR 293 ATI Pharmacology Final Review

NR 293 ATI Pharmacology Final Review bacteriostatic - ANS drugs that do not kill the bacteria, but slows their growth culture and sensitivity - ANS take a blood culture so we can determine where the bacteria is growing; sensitivity report determines the best treatment antibiotic combos - ANS Additive potentiative antagonistic empiric therapy - ANS treatment of an infection before specific culture information has been obtained definitive therapy - ANS antibiotic therapy tailored to treat organisms identified with cultures prophylactic therapy - ANS treatment with antibiotics to prevent an infection, as in intraabdominal surgery or after trauma MOA of sulfonamides - ANS Bacteriostatic inhibit bacterial growth prevent bacterial synthesis of folic acid uses of sulfonamides - ANS Gramp positive and negative, broad spectrum respiratory tract infections infections of the small bowel UTIs: enterobacter, ecoli, klebsiella, proteus vulgaris, staphylococcus aureus contraindications of sulfonamides - ANS drug allergy pregnant women infants younger than 2 months potassium oral contraceptives (ineffective) Adverse effects of sulfonamides - ANS mild to moderate rash photosensitivity GI distress stomatitis crystalluria fatigue depression headache dizziness blood dyscrasias Steven Johnsons syndrome renal failure hyperkalemia prototype for sulfonamides, and administration - ANS sulfamethoxazole combined with trimethropim Administered IV, PO, Topical patient education/ nursing interventions for sulfonamides - ANS Pt. Education: take with a full glass of water increase fluid intake report sore throat, bruising, bleeding avoid direct sunlight Nursing interventions: push fluids