TEST BANK
ABRAMS’ CLINICAL DRUG THERAPY RATIONALES FOR NURSING
PRACTICE 12TH EDITION
GERALYN FRANDSEN
,Test Generator Questions, Chapter 1, The Foundation of
Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed
oral paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
Answer: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease
process. In this case, paroxetine hydrochloride will control the symptoms but not
cure the disorder. Drugs with local effects, such as sunscreen and local anesthetics,
act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly,
or intravenously.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Introduction
2. A client has been prescribed an antibiotic. This medication is a naturally
occurring substance that has been chemically modified. What is another name for
this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
,Answer: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more
standardized in their chemical characteristics, more consistent in their effects, and
less likely to produce allergic reactions. Biotechnology drugs involve manipulating
DNA and RNA and recombining genes into hybrid molecules that can be inserted
into living organisms. Prototype drugs are the first drug of a particular group to be
developed.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Drug Sources
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
Answer: A
Rationale: Drugs are classified according to their effects on particular body
systems, their therapeutic uses, and their chemical characteristics. Morphine is
classified as a central nervous system depressant and will produce this effect in the
client. A central nervous system stimulant increases attention and raises mood. An
anti-inflammatory agent decreases inflammation at the site of tissue or joint
inflammation. An antihypertensive agent reduces blood pressure.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Drug Classifications and Prototypes
,4. A client is administered amoxicillin. The generic name of this medication belongs
to which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
Answer: C
Rationale: The generic name often indicates the drug group (e.g., drugs with
generic names ending in “cillin” are penicillins). Selective serotonin reuptake
inhibitors are medications that have antidepressant effects; SSRI is a broad
classification, not a generic name. Diuretics are medications that increase urine
output; diuretic is a broad classification, not a generic name. ACE inhibitor is the
broad classification for the angiotensin receptor blockers, not the generic name.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 2
Reference: p. 3, Drug Names
5. The administration of diphenhydramine is regulated by which U.S. government
agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
Answer: D
Rationale: The Food and Drug Administration approves drugs for over-the-counter
availability, including the transfer of drugs from prescription to OTC status, and
,may require clinical trials to determine the safety and effectiveness of OTC use. The
Public Health Service is regulated by the state to maintain the health of individual
citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation. The Occupational Safety and Health Administration regulates
safety within the workplace.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 4
Reference: p. 4, Prescription and Nonprescription Drugs
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
Answer: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants, hallucinogens,
and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and
broadened FDA powers and responsibilities, giving the FDA control over drug
safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics.
The Sherley Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 3
Reference: p. 4, Prescription and Nonprescription Drugs
7. A nurse is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by
,which U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
Answer: C
Rationale: The Drug Enforcement Administration enforces the Controlled
Substances Act. Under this enforcement, nurses are responsible for storing
controlled substances in locked containers, administering them only to the people
for whom they are prescribed, recording each dose given, and maintaining an
accurate inventory. The Food, Drug, and Cosmetic Act of 1938 revised and
broadened FDA powers and responsibilities, giving the FDA control over drug
safety. The Public Health Service is regulated by the state to maintain the health of
individual citizens of the state. The Sherley Amendment of 1912 prohibited
fraudulent claims of drug effectiveness.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 4
Reference: p. 7, Testing Procedure
8. In Phase 1 clinical trials, the potential uses and effects of a new drug are
determined by which method?
A. Administering doses to healthy volunteers
B. Administering doses to people with the disease
C. Administering in placebo-controlled design
D. Calculating the risk-to-benefit ratio
Answer: A
Rationale: Phase 1 studies allow for the administration of the medication to healthy
volunteers to determine safe dosages, routes of administration, absorption,
metabolism, excretion, and toxicity. In Phase 2 studies, a few doses are given to a
certain number of subjects with the disease or symptom for which the drug is being
,studied and responses are compared with those of healthy subjects. Placebo-
controlled designs are used in Phase 3 studies, in which half of the subjects receive
the new drug and half receive the placebo. Calculating the risk-to-benefit ratio is
used in Phase 2 studies to determine whether the potential benefits of the drug
outweigh the risks.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
9. A new medication for the treatment of Alzheimer’s disease is being administered
to a group of subjects with the disease. The subjects receiving this medication are
unaware of whether they are being administered the medication or a placebo. This
testing occurs in which phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
Answer: C
Rationale: In Phase 3, the drug is given to a larger and more representative group
of subjects. In double-blind, placebo-controlled designs, half of the subjects receive
the new drug and half receive a placebo (an inactive substance similar in
appearance to the actual drug), with neither subjects nor researchers knowing
which subjects receive which formulation. In Phase 1, a few doses are given to a
certain number of healthy volunteers to determine safe dosages, routes of
administration, absorption, metabolism, excretion, and toxicity. In Phase 2, a few
doses are given to a certain number of subjects with the disease or symptom for
which the drug is being studied and responses are compared with those of healthy
subjects. In Phase 4, the FDA evaluates the data from the first three phases for
drug safety and effectiveness, allows the drug to be marketed for general use, and
requires manufacturers to continue monitoring the drug’s effects.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
,Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
10. Which organization is responsible for approving new drugs in the United States?
A. The American Medical Association (AMA)
B. The American Pharmaceutical Association (APA)
C. The Food and Drug Administration (FDA)
D. The U.S. Pharmacopeia
Answer: C
Rationale: The Food and Drug Administration is responsible for approving new
drugs in the United States. The American Medical Association represents the health
care providers of the United States. The American Pharmaceutical Association
represents the pharmacists of the United States. The U.S. Pharmacopeia was
adopted in 1906 and is issued every 5 years under the supervision of a national
committee of pharmacists, scientists, and health care providers to provide
information concerning drug purity and strength.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Safe and Effective Care Environment: Management of Care
Integrated Process: Nursing process
Objective: 3
Reference: p. 7, Testing Procedure
11. A client with a long-standing dermatologic health problem has been advised to
use a drug with a local effect. The nurse should recognize what characteristic of this
drug?
A. It affects only the organ system in which it is metabolized.
B. The drug requires application at multiple sites.
C. It is effective only as long as it is in contact with skin.
D. The drug acts primarily at the site where it is applied.
,Answer: D
Rationale: Drugs with local effects, such as sunscreen lotions and local anesthetics,
act mainly at the site of application. Those with systemic effects are taken into the
body, circulated through the bloodstream to their sites of action in various body
tissues, and eventually eliminated from the body. A drug with local effect does not
necessarily have to be applied at multiple sites, and its action may affect tissues
long after contact.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Introduction
12. What is the primary importance of a black box warning?
A. It will result in the medication being removed from the market.
B. It acknowledges that the medication has been tested on only a selected portion
of the population.
C. It suggests that the prescription of the medication be avoided when treating
certain populations.
D. It alerts health care professionals of the potential of serious adverse effects
associated with the medication.
Answer: D
Rationale: Black box warnings identify the fact that a drug can cause serious
adverse effects. Subsequent withdrawal of approved and marketed drugs has
occurred, usually because of serious adverse effects that become evident only when
the drugs are used in a large, diverse population. The warning does not address
testing or target populations.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
, Integrated Process: Nursing process
Objective: 4
Reference: p. 7, Testing Procedure
13. A health care facility is complying with the mandates of U.S. The Drug
Enforcement Administration (DEA) concerning Schedule II medications when
implementing which nursing intervention? Select all that apply.
A. Access to narcotics is controlled by key or codes.
B. Narcotics are administered by prescriptions only.
C. Only selected narcotics may be automatically renewed.
D. The administration of individual narcotic doses is recorded in specific unit
documentation.
E. Any recognized discrepancy involving a narcotic must be reported to the
appropriate facility authority.
Answer: A, B, D, E
Rationale: Nurses are responsible for storing controlled substances in locked
containers, administering them only to the people for whom they are prescribed,
recording each dose given on agency narcotic sheets and on the client’s medication
administration record, maintaining an accurate inventory, and reporting
discrepancies to the proper authorities. Prescriptions for Schedule II drugs cannot
be refilled; a new prescription is required.
Question format: Multiple Select
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
14. Which medication reference is considered to be an authoritative, well-respected
source of information? Select all that apply.
A. American Hospital Formulary Service
B. Drug Facts and Comparisons
C. Physicians’ Desk Reference
D. Lippincott’s Nursing Drug Guide
ABRAMS’ CLINICAL DRUG THERAPY RATIONALES FOR NURSING
PRACTICE 12TH EDITION
GERALYN FRANDSEN
,Test Generator Questions, Chapter 1, The Foundation of
Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed
oral paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
Answer: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease
process. In this case, paroxetine hydrochloride will control the symptoms but not
cure the disorder. Drugs with local effects, such as sunscreen and local anesthetics,
act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly,
or intravenously.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Introduction
2. A client has been prescribed an antibiotic. This medication is a naturally
occurring substance that has been chemically modified. What is another name for
this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
,Answer: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more
standardized in their chemical characteristics, more consistent in their effects, and
less likely to produce allergic reactions. Biotechnology drugs involve manipulating
DNA and RNA and recombining genes into hybrid molecules that can be inserted
into living organisms. Prototype drugs are the first drug of a particular group to be
developed.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Drug Sources
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
Answer: A
Rationale: Drugs are classified according to their effects on particular body
systems, their therapeutic uses, and their chemical characteristics. Morphine is
classified as a central nervous system depressant and will produce this effect in the
client. A central nervous system stimulant increases attention and raises mood. An
anti-inflammatory agent decreases inflammation at the site of tissue or joint
inflammation. An antihypertensive agent reduces blood pressure.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Drug Classifications and Prototypes
,4. A client is administered amoxicillin. The generic name of this medication belongs
to which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
Answer: C
Rationale: The generic name often indicates the drug group (e.g., drugs with
generic names ending in “cillin” are penicillins). Selective serotonin reuptake
inhibitors are medications that have antidepressant effects; SSRI is a broad
classification, not a generic name. Diuretics are medications that increase urine
output; diuretic is a broad classification, not a generic name. ACE inhibitor is the
broad classification for the angiotensin receptor blockers, not the generic name.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 2
Reference: p. 3, Drug Names
5. The administration of diphenhydramine is regulated by which U.S. government
agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
Answer: D
Rationale: The Food and Drug Administration approves drugs for over-the-counter
availability, including the transfer of drugs from prescription to OTC status, and
,may require clinical trials to determine the safety and effectiveness of OTC use. The
Public Health Service is regulated by the state to maintain the health of individual
citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation. The Occupational Safety and Health Administration regulates
safety within the workplace.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 4
Reference: p. 4, Prescription and Nonprescription Drugs
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
Answer: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants, hallucinogens,
and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and
broadened FDA powers and responsibilities, giving the FDA control over drug
safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics.
The Sherley Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 3
Reference: p. 4, Prescription and Nonprescription Drugs
7. A nurse is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by
,which U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
Answer: C
Rationale: The Drug Enforcement Administration enforces the Controlled
Substances Act. Under this enforcement, nurses are responsible for storing
controlled substances in locked containers, administering them only to the people
for whom they are prescribed, recording each dose given, and maintaining an
accurate inventory. The Food, Drug, and Cosmetic Act of 1938 revised and
broadened FDA powers and responsibilities, giving the FDA control over drug
safety. The Public Health Service is regulated by the state to maintain the health of
individual citizens of the state. The Sherley Amendment of 1912 prohibited
fraudulent claims of drug effectiveness.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 4
Reference: p. 7, Testing Procedure
8. In Phase 1 clinical trials, the potential uses and effects of a new drug are
determined by which method?
A. Administering doses to healthy volunteers
B. Administering doses to people with the disease
C. Administering in placebo-controlled design
D. Calculating the risk-to-benefit ratio
Answer: A
Rationale: Phase 1 studies allow for the administration of the medication to healthy
volunteers to determine safe dosages, routes of administration, absorption,
metabolism, excretion, and toxicity. In Phase 2 studies, a few doses are given to a
certain number of subjects with the disease or symptom for which the drug is being
,studied and responses are compared with those of healthy subjects. Placebo-
controlled designs are used in Phase 3 studies, in which half of the subjects receive
the new drug and half receive the placebo. Calculating the risk-to-benefit ratio is
used in Phase 2 studies to determine whether the potential benefits of the drug
outweigh the risks.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
9. A new medication for the treatment of Alzheimer’s disease is being administered
to a group of subjects with the disease. The subjects receiving this medication are
unaware of whether they are being administered the medication or a placebo. This
testing occurs in which phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
Answer: C
Rationale: In Phase 3, the drug is given to a larger and more representative group
of subjects. In double-blind, placebo-controlled designs, half of the subjects receive
the new drug and half receive a placebo (an inactive substance similar in
appearance to the actual drug), with neither subjects nor researchers knowing
which subjects receive which formulation. In Phase 1, a few doses are given to a
certain number of healthy volunteers to determine safe dosages, routes of
administration, absorption, metabolism, excretion, and toxicity. In Phase 2, a few
doses are given to a certain number of subjects with the disease or symptom for
which the drug is being studied and responses are compared with those of healthy
subjects. In Phase 4, the FDA evaluates the data from the first three phases for
drug safety and effectiveness, allows the drug to be marketed for general use, and
requires manufacturers to continue monitoring the drug’s effects.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
,Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
10. Which organization is responsible for approving new drugs in the United States?
A. The American Medical Association (AMA)
B. The American Pharmaceutical Association (APA)
C. The Food and Drug Administration (FDA)
D. The U.S. Pharmacopeia
Answer: C
Rationale: The Food and Drug Administration is responsible for approving new
drugs in the United States. The American Medical Association represents the health
care providers of the United States. The American Pharmaceutical Association
represents the pharmacists of the United States. The U.S. Pharmacopeia was
adopted in 1906 and is issued every 5 years under the supervision of a national
committee of pharmacists, scientists, and health care providers to provide
information concerning drug purity and strength.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Remember
Client Needs: Safe and Effective Care Environment: Management of Care
Integrated Process: Nursing process
Objective: 3
Reference: p. 7, Testing Procedure
11. A client with a long-standing dermatologic health problem has been advised to
use a drug with a local effect. The nurse should recognize what characteristic of this
drug?
A. It affects only the organ system in which it is metabolized.
B. The drug requires application at multiple sites.
C. It is effective only as long as it is in contact with skin.
D. The drug acts primarily at the site where it is applied.
,Answer: D
Rationale: Drugs with local effects, such as sunscreen lotions and local anesthetics,
act mainly at the site of application. Those with systemic effects are taken into the
body, circulated through the bloodstream to their sites of action in various body
tissues, and eventually eliminated from the body. A drug with local effect does not
necessarily have to be applied at multiple sites, and its action may affect tissues
long after contact.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 1
Reference: p. 3, Introduction
12. What is the primary importance of a black box warning?
A. It will result in the medication being removed from the market.
B. It acknowledges that the medication has been tested on only a selected portion
of the population.
C. It suggests that the prescription of the medication be avoided when treating
certain populations.
D. It alerts health care professionals of the potential of serious adverse effects
associated with the medication.
Answer: D
Rationale: Black box warnings identify the fact that a drug can cause serious
adverse effects. Subsequent withdrawal of approved and marketed drugs has
occurred, usually because of serious adverse effects that become evident only when
the drugs are used in a large, diverse population. The warning does not address
testing or target populations.
Question format: Multiple Choice
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
, Integrated Process: Nursing process
Objective: 4
Reference: p. 7, Testing Procedure
13. A health care facility is complying with the mandates of U.S. The Drug
Enforcement Administration (DEA) concerning Schedule II medications when
implementing which nursing intervention? Select all that apply.
A. Access to narcotics is controlled by key or codes.
B. Narcotics are administered by prescriptions only.
C. Only selected narcotics may be automatically renewed.
D. The administration of individual narcotic doses is recorded in specific unit
documentation.
E. Any recognized discrepancy involving a narcotic must be reported to the
appropriate facility authority.
Answer: A, B, D, E
Rationale: Nurses are responsible for storing controlled substances in locked
containers, administering them only to the people for whom they are prescribed,
recording each dose given on agency narcotic sheets and on the client’s medication
administration record, maintaining an accurate inventory, and reporting
discrepancies to the proper authorities. Prescriptions for Schedule II drugs cannot
be refilled; a new prescription is required.
Question format: Multiple Select
Chapter 1: The Foundation of Pharmacology: Quality and Safety
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Integrated Process: Nursing process
Objective: 5
Reference: p. 7, Testing Procedure
14. Which medication reference is considered to be an authoritative, well-respected
source of information? Select all that apply.
A. American Hospital Formulary Service
B. Drug Facts and Comparisons
C. Physicians’ Desk Reference
D. Lippincott’s Nursing Drug Guide
