ORAL
MANIFESTATIONS OF
. DERMATOLOGICAL
DISORDERS.
,• Dermatological diseases, besides involving the skin and its appendages may also involve the oral cavity. The l
oral cavity in dermatological disorders deserve special attention, considering that they may be the presenting
feature or the only sign of these disorders.
• Oral cavity encompasses a diverse group of anatomical structures, including teeth and oral mucous membran
• An oral mucosal lesion (OML) is defined as any abnormal change or any swelling on the oral mucosal surface
• It may be a result of local pathology or secondary to other systemic disease, including those of skin.
• OML may be primary clinical feature or the only sign of these disorders.
• A prevelance of 35% of OML in patients affected with dermatological conditions has been observed.
,Various groups of dermatological diseases associated
with OML are as follows:
☆ Infections
☆Vesicobullous disorders
☆ Lichen planus and other lichenoid disorders
☆Collagen vascular diseases
☆Vasculitic
☆ Genodermatosis
☆Miscellaneous
Pemphigus vulgaris, lichen planus, candidiasis and recurrent apthous ulcers were the most frequently diagn
conditions
, Infections
Herpes simplex
• Herpes simplex is caused by the herpes simplex virus(HSV) . There are two major antigenic types, of which typ
classically associated with oral mucosal lesions. Primary infection is often subclinical When clinical lesions dev
gingivostomatitis is the most common clinical manifestation.
• Most cases occur in children and begin with fever, malaise and excessive dribbling.
• The gums are swollen and bleed easily. Vesicles presenting as white plaques and ulcers with a yellowish pseud
are seen throughout oral mucosa
• Recurrences occur in 30–50% of cases of oral herpes and do not affect the buccal mucosa, but labial lesions ar
Varicella zoster virus
The varicella zoster virus (VZV) is the cause of both varicella and zoster.
Varicella
•After an incubation period of 14–17 days, fever and malaise, is followed by the development of papules in crops
rapidly become clear, unilocular vesicles. In 2–4 days a dry crust forms, soon separates and heals without scarring
vesicles are common in the mouth, especially on the palate, and are occasionally seen on other mucous membra
MANIFESTATIONS OF
. DERMATOLOGICAL
DISORDERS.
,• Dermatological diseases, besides involving the skin and its appendages may also involve the oral cavity. The l
oral cavity in dermatological disorders deserve special attention, considering that they may be the presenting
feature or the only sign of these disorders.
• Oral cavity encompasses a diverse group of anatomical structures, including teeth and oral mucous membran
• An oral mucosal lesion (OML) is defined as any abnormal change or any swelling on the oral mucosal surface
• It may be a result of local pathology or secondary to other systemic disease, including those of skin.
• OML may be primary clinical feature or the only sign of these disorders.
• A prevelance of 35% of OML in patients affected with dermatological conditions has been observed.
,Various groups of dermatological diseases associated
with OML are as follows:
☆ Infections
☆Vesicobullous disorders
☆ Lichen planus and other lichenoid disorders
☆Collagen vascular diseases
☆Vasculitic
☆ Genodermatosis
☆Miscellaneous
Pemphigus vulgaris, lichen planus, candidiasis and recurrent apthous ulcers were the most frequently diagn
conditions
, Infections
Herpes simplex
• Herpes simplex is caused by the herpes simplex virus(HSV) . There are two major antigenic types, of which typ
classically associated with oral mucosal lesions. Primary infection is often subclinical When clinical lesions dev
gingivostomatitis is the most common clinical manifestation.
• Most cases occur in children and begin with fever, malaise and excessive dribbling.
• The gums are swollen and bleed easily. Vesicles presenting as white plaques and ulcers with a yellowish pseud
are seen throughout oral mucosa
• Recurrences occur in 30–50% of cases of oral herpes and do not affect the buccal mucosa, but labial lesions ar
Varicella zoster virus
The varicella zoster virus (VZV) is the cause of both varicella and zoster.
Varicella
•After an incubation period of 14–17 days, fever and malaise, is followed by the development of papules in crops
rapidly become clear, unilocular vesicles. In 2–4 days a dry crust forms, soon separates and heals without scarring
vesicles are common in the mouth, especially on the palate, and are occasionally seen on other mucous membra