Advanced Pathophysiology Week 3 Quiz- Version 3

Advanced Pathophysiology Week 3 Quiz- Version 3 Question 1 0 / 2 pts Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia? Correct Answer Sideroblastic Pernicious You Answered Iron deficiency Aplastic Mild to moderate enlargement of the spleen (splenomegaly) and liver (hepatomegaly) occurs. Occasionally, abnormal skin pigmentation (bronze colored) is seen. Heart rhythm disturbances, along with congestive heart failure, are major life-threatening complications related to cardiac iron overload. Question 2 2 / 2 pts What is the pathophysiologic process of aplastic anemia? Inherited genetic disorder with recessive X-linked transmission Autoimmune disease against hematopoiesis by activated immunoglobulins Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells Correct! Autoimmune disease against hematopoiesis by activated cytotoxic T cells Most cases of AA result from an autoimmune disease directed against hematopoietic stem cells. Cytotoxic T cells (Tc cells) appear to be the main culprits. Question 3 2 / 2 pts Which anemia produces small, pale erythrocytes? Hemolytic Folic acid Pernicious Correct!