Advanced Pathophysiology Week 6 Quiz

Advanced Pathophysiology Week 6 Quiz Question 1 2 / 2 pts _____ is a chronic inflammatory joint disease characterized by stiffening and fusion of the spine and sacroiliac joints. Fibromyalgia Ankylosing spondylitis Paget disease You Answered Rheumatoid arthritis Ankylosing spondylitis (AS) (spondyloarthritis) is a chronic, inflammatory joint disease characterized by stiffening and fusion (ankylosis) of the spine and sacroiliac joints. Question 2 2 / 2 pts Considering the pathophysiology of osteoporosis, what are the effects of extracellular signal regulated kinases (ERKs) and receptor activator of RANKL on osteoblasts and osteoclasts? Correct! ERKs and RANKL increase the life span of osteoclasts and decrease the life span of osteoblasts. ERKs and RANKL increase the life span of osteoblasts and decrease the life span of osteoclasts. ERKs increase the life span of osteoclasts and RANKL decreases the life span of osteoblasts. ERKs increase the life span of osteoblasts and RANKL decreases the life span of osteoclasts. In addition to ERKs, RANKL is required for the antiapoptotic and thus longer life span of osteoclasts. These effects increase the life span of osteoclasts (i.e., longer bone resorbing) and shorten the life span of the bone-forming cells, or osteoblasts. Question 3 2 / 2 pts Rhabdomyolysis is characterized by lysis of skeletal muscle cells through the initiation of the complement cascade. paralysis of skeletal muscles resulting from impaired nerve supply. smooth muscle degeneration resulting from ischemia. Correct! release of myoglobin from damaged striated muscle cells.