ONS ONCC Chemo Renewal Updated 2023
Questions With 100% Correct Solutions
Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It
only changes the timing of treatment and can change surgical options if the tumor is
shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation
therapy instead of needing a mastectomy - Correct answer-Main benefit of neoadjuvant
chemotherapy (breast cancer patient)
A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess
life expectancy and risk of morbidity and mortality in the older patient. This assessment
tool would evaluate and include the following areas: functional status, socioeconomic
issues, psychosocial distress, comorbidities, cognitive function, nutritional status,
polypharmacy, and a medication review (NCCN Older Adult Oncology Guidelines,
version 1.2015). - Correct answer-Due to Mrs. Turner's age and comorbidities, her
oncologist performs a comprehensive geriatric assessment. You know that this
assessment covers all but which of the following:
65 - Correct answer-The NCCN Older Adult Oncology Guidelines (version 1.2015)
provides information on what is included in a comprehensive geriatric assessment.
Currently, more than 60% of cancers in the United States occur in people age
______and older and as the oncology world ages, nearly half (46%) of cancer survivors
are 70 years of age or older
Two of the agents (docetaxel and carboplatin) that Mrs. Turner will receive are
categorized as irritants. Docetaxel can cause a significant reaction if it extravasates. It
can lead to edema, erythema, occasional pain and blister formation (ONS Chemo/Bio
guidelines, 2014). That is the most likely reason that Mrs. Turner was given a port for
her treatments. Some patients will receive their treatments through a peripheral IV
without incident. Just because they are intravenous agents does not mean that a port is
required and needing a port has nothing to do with her being older in age. Since none of
these agents are vesicants, they likely could have been given safely via peripheral route
but having a port placed is OK as well. - Correct answer-What is your best explanation
for why Mrs. Turner was given a port to receive her chemotherapy?
Irrirtants - Correct answer-_____________can cause inflammation, pain, and burning
but rarely cause tissue necrosis comparable to a vesicant (unless a large amount or a
very high concentration of the irritant is extravasated).
Vesicants - Correct answer-_____________can cause blistering and significant pain
and tissue damage and destruction, leading to tissue death.
, Non-DNA-binding solutions remain in the local area of the extravasation, which
improves the possibility of drug deactivation.
DNA-binding agents attach to DNA nucleic acids, causing the antagonist to be ingested
cellularly, leading to progressive tissue destruction - Correct answer-A further
classification of an antineoplastic agent's potential to cause damage is whether its
mechanism of action includes DNA binding.
Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin - Correct answer-DNA Binding Irritants
Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - Correct answer-DNA Nonbinding vessicants
Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures. - Correct answer-Extravasciation Alkylating / Mechlorethamine
tx
Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days - Correct answer-Extravasciation Alkylating: Oxaliplatin
Totect
Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
Questions With 100% Correct Solutions
Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It
only changes the timing of treatment and can change surgical options if the tumor is
shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation
therapy instead of needing a mastectomy - Correct answer-Main benefit of neoadjuvant
chemotherapy (breast cancer patient)
A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess
life expectancy and risk of morbidity and mortality in the older patient. This assessment
tool would evaluate and include the following areas: functional status, socioeconomic
issues, psychosocial distress, comorbidities, cognitive function, nutritional status,
polypharmacy, and a medication review (NCCN Older Adult Oncology Guidelines,
version 1.2015). - Correct answer-Due to Mrs. Turner's age and comorbidities, her
oncologist performs a comprehensive geriatric assessment. You know that this
assessment covers all but which of the following:
65 - Correct answer-The NCCN Older Adult Oncology Guidelines (version 1.2015)
provides information on what is included in a comprehensive geriatric assessment.
Currently, more than 60% of cancers in the United States occur in people age
______and older and as the oncology world ages, nearly half (46%) of cancer survivors
are 70 years of age or older
Two of the agents (docetaxel and carboplatin) that Mrs. Turner will receive are
categorized as irritants. Docetaxel can cause a significant reaction if it extravasates. It
can lead to edema, erythema, occasional pain and blister formation (ONS Chemo/Bio
guidelines, 2014). That is the most likely reason that Mrs. Turner was given a port for
her treatments. Some patients will receive their treatments through a peripheral IV
without incident. Just because they are intravenous agents does not mean that a port is
required and needing a port has nothing to do with her being older in age. Since none of
these agents are vesicants, they likely could have been given safely via peripheral route
but having a port placed is OK as well. - Correct answer-What is your best explanation
for why Mrs. Turner was given a port to receive her chemotherapy?
Irrirtants - Correct answer-_____________can cause inflammation, pain, and burning
but rarely cause tissue necrosis comparable to a vesicant (unless a large amount or a
very high concentration of the irritant is extravasated).
Vesicants - Correct answer-_____________can cause blistering and significant pain
and tissue damage and destruction, leading to tissue death.
, Non-DNA-binding solutions remain in the local area of the extravasation, which
improves the possibility of drug deactivation.
DNA-binding agents attach to DNA nucleic acids, causing the antagonist to be ingested
cellularly, leading to progressive tissue destruction - Correct answer-A further
classification of an antineoplastic agent's potential to cause damage is whether its
mechanism of action includes DNA binding.
Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin - Correct answer-DNA Binding Irritants
Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - Correct answer-DNA Nonbinding vessicants
Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures. - Correct answer-Extravasciation Alkylating / Mechlorethamine
tx
Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days - Correct answer-Extravasciation Alkylating: Oxaliplatin
Totect
Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
