1. How many milliliter of U-100 insulin should be used to obtain 50units of insulin?
a. 5ml b. 50mL c. 0.5mL d.500mL
2. How many drops would be prescribed in each dose of a liquid medicine if 20mL contained 60 doses? The
dropper calibrates 35gtts per mL.
a. 12gtts b.15gtts c. 8gtts d. 23gtts
3. How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain 1/10
grain? a. 58mg b. 480mg c. 4800mg d. 4.8mg
4. If a pint of a certain liquid weights 9200 grains, what is the specific gravity of the
liquid? a. 1.0 b. 1.32 c. 1.276 d. 1.26
5. How many grams of dextrose are required to prepare 4500 L of a 5%
solution? a. 80,000 gb. 225,000 g c. 4 f3 d. 8 f3
6. How many grams of drug substance should be dissolved in 250 mL of water to make a 5%(w/w)
solution? a. 9.6g b.13.16g c.60 g d. 10g
7. Convert 5% to mg/mL
a. 50mg/mL b.500mg/mL c.5000mg/mL d. 5mg/mL
8. In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70% alcohol?
a. 3parts/5parts b.1part/1part c.5parts/4parts d.4parts/5parts
9. How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to prepare
1500mL of a liquid having a specific gravity of 0.925?
a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875) b.2250mL (sp.gr 0.950) 1125mL (sp gr 0.875) c.500mL
(sp.gr 0.950) 1000mL(sp gr 0.875) d. 1125mL (sp.gr 0.950) 2250mL(sp gr 0.875)
10. Zinc chloride is a three-ion electrolyte,dissociating 80% in a certain concentration. Calculate its dissociation
factor(I)
a. 2.6 b. 1.6 c. 2.9 d. 3
11. If 10mg of a drug are added to a 500mL large-volume parenteral fluid, what should be the rate of flow, in
mL/hr, to deliver 1mg of drug per hour?
a. 50mL/hr b. 20mL/hr c.500mL/hr d.5mL/hr
12. How many milliequivalents are there in 15mL of a 50% MgSO4 solution? (mol wt= 246)
a. 6.097 mEq b. 60.97 mEq c. 6.96 mEq d.69.7 mEq
13.You are directed to weigh 10g of substance so as to limit the error to 0.2%. calculate the maximum potential
error, in terms of grams, that you would not be permitted to exceed.
a. 0.05g b. 0.02g c. 0.002g d. 0.2g
14. A prescription is to taken as follows: 1 tab q.i.d. the first day; 1 tab t.i.d. the second day; 1 tab b.i.d. x 5 d;
and 1 tab q.d. thereafter. How many tablets should be dispensed to equal a 3-day supply?
a. 18 tab b. 40 tab c. 22 tab d. 47 tab
15. Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given oral
tetracycline in doses of 0.011g/lb body weight every 6 hrs. express the doses of milligrams per kilogram
of body weight.
a. 5mg/kg b.24.2mg/kg c.25mg/kg d. 11mg/kg
16. How many cochicines tablets, each containing 00mcg, may be prepared from 30g of
colchicines? a. 50,000 tab b.20,000 tab c.20 tab d.50 tab
17. Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. how many milliliters
would provide dose of 40 mcg?
a. 0.04mL b. 40mL c. 40mL d. 0.4mL
18. Nitrostat sublingual tablets are available as 1/200gr tablets. What is the approximate equivalent
in milligrams?
a. 0.325 b. 0.077 c. 0.005 d. 0.65
19. Four thousand nanograms equals 4:
a. centigrams b. grams c. milligrams d. micrograms
20. If a physician prescribed 4g of aspirin to be taken by a patient daily, about how many 5-grain tablets
should the patient take each day?
a. 10 tab b. 12 tab c.15 tab d.8 tab
,24. Pico denotes of the basic unit
a. 10 -12
b. 10 -15
c.10-18 d. 10-10
25. 1 milliliter is 1000x greater than:
a. microliter b.picoliter c.nanoliter d.liter
26. Sudafed cough syrup contains 0.0g of dextromethorphan hydrobromide in each fluidounce. How many
milligrams of this agent would be present in each teaspoonful dose?
a. 10mg b. 12mg c. 15mg d. 20mg
27. The usual dose of digoxin for rapid digitalization is a total of 1.0mg, divide into two or more portion at
intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50mcg/mL would provide this
dose?
a. 15mL b. 10mL c.25mL d.20mL
28. The dose of beclamethasone, an aerosolized inhalant, is 200mcg twice daily. The commercial inhaler
delivers 50mcg per metered inhalation and contains 200 inhalations. How many inhalers should be dispensed to
a patient if a 60-day supply is prescribed?
a. 3 b.2 c. 4 d.5
29. If a physician prescribed Keflex, 250mg q.i.d. x 10 days, how many milliliters of keflex
suspension containing 250mg per 5 mL should be dispensed?
a. 250mL b.200mL c. 150mL d.100mL
30. Terpin hydrate and codeine elixir contains 60mg of codeine per 30mL. how much additional codeine should
be added to 180mL of the elixir so that each teaspoonful will contain 15mg of codeine?
a. 180mg b.200mg c.170mg d.190mg
31. The directions intended for the patient on a prescription read 1tbsp a.c. and h.s. for 10days. What is the
minimum volume the pharmacist should dispense?
a. 200mL b. 150mL c. 600mL d. 450mL
32. If the cost of human growth hormone is P40/mg q4h six times daily. How many will a 180lb patient
receive daily?
a. 12mg b. 164mg c.650mg d.980mg
33. The pediatric dose of cefadroxil is 30mg/kg/day. If a child was given a daily dose of 2 teaspoonfuls of
pediatric suspension containing 125mg of cefadroxil per 5mL, what was the weight, in pounds of the
child?
a. 19lbs b. 17.3lbs c. 18.3lbs d. 18.5lbs
34. A ferrous sulfate syrup contains 220mg of FeSO4.7H2O per teaspoon dose. How many milligrams of
elemental iron are present in the dose? (mol wt FeSO4.7H2O= 278; at wt of Fe=55.9, S=32.1, O=16, H=1.0)
a. 44mg b. 50mg c. 88mg d. 100mg
35. An antacid tablet contains 80mg of dried aluminum hydroxide gel and 20g of magnesium trisilicate. How
many kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product, each
containing 100 tablets?
a.2000kg b.20000kg c.200kg d.8000kg
36. An estradiol transdermal system contains in each skin patch 4mg of estradiol and 0.3mL of alcohol.
How many liters of alcohol would be required to manufacture a half-million patches?
a. 15L b. 150L c. 1500L d. 300L
37. From the ff formula:
Benzyl benzoate 250mL
Triethanolamine 5mL
Purified water, to make 1000mL
Calculate the quantity of benzyl benzoate required to make 6fl.Oz of benzyl benzoate lotion
a.45mL b. 40mL c. 4.5mL d. 25mL
38. If 150mL of polyethylene glycol 400 weighs 74.1g, what is its specific
gravity? a. 0.88 b. 0.494 c. 2.35 d. 1.3
39. A sunscreen lotion contains 5g of methyl salicylate (sp gr 1.045) per 1000mL. how many milliliters
of methyl salicylate should be used in preparing 1gallon of the lotion?
a. 189.25mL b. 197.77mL c. 181.10mL d. 190mL
40. Cocoa butter, which is solid at room temperature and melts at 34°C, has a specific gravity of 0.86. If a
, 43. If an intravenous dose of mannitol is 1.5% (w/v) sodium chloride solution can be made from 1 lb of sodium
chloride?
a. 50,444 mL b. 30,000 mL c. 50, 400 mL d. 1,000 mL
44. If 10mL of a nitroglycerin injection (5mg of nitroglycerin per milliliter) are added to make a liter of
intravenous fluid, what is the percentage (w/v) of nitroglycerin in the final product?
a. 0.025% b. 0.05% c. 0.005% d. 0.0005%
45. How many milliliters of resorcinol monoacetate should be used to prepare 1 pint of a 15% (v/v) lotion?
a. 71mL b. 65 mL c. 76 mL d. 69 mL
46. How many liters of a mouthwash can be prepared from 100mL of cinnamon flavor if its concentration is
to be 0.5% (v/v)?
a. 10L b. 20L c. 15L d. 18 L
47. One pound of a fungicidal ointment contains 9.08g of undecylenic acid. Calculate the percentage (w/w)
of undecylenic acid in the ointment.
a. 1.81% b. 1.5% c. 2% d. 2.5%
48. A vaginal foam contains 0.01% (w/v) of dienestrol. Express this concentration as a ration strength.
a. 1:100 b. 1:1,000 c. 1:1,000,000,000 d. 1:10,000
49. A sample of white petrolatum contains 10mg of tocopherol per kilogram as a preservative. Express
the amount of tocopherol as a ratio strength.
a. 1:100,000 b. 1:1,000 c. 1:1,000,000 d. 1:10,000
50. Hepatitis B immune globulin is preserved with 1:10,000 w/v of thimerosal. If the dose of the injection is
0.06 mL/Kg of body weight, how many micrograms of thimerosal would be contained in the dose for a 150-lb
patient?
a. 400mcg b. 409mcg c. 415 mcg d. 450mcg
51. What is the percent concentration of cholesterol in a patient’s blood serum if the cholesterol level is
determined to be 260mg %?
a. 2.6% b. 26% c. 0.26% d. 0.026%
52. If a serum sample is determined to contain 270mg/dL of cholesterol, what is the concentration of
cholesterol (mol wt 386) in terms of millimoles per liter?
a. 6.5mmol/L b. 6.9mmol/L c. 69.9mmol/L d. 5.66mmol/L
53. A glucose meter shows that a patient’s blood contains 125mg% of glucose. Express this value as
mg/mL. a. 1.25mg/mL b. 12.5mg/mL c. 125mg/mL d. 0.125mg/mL
54. If 250mL of a 1:800 (v/v) solution are diluted to 1000mL, what will be the ration strength
(v/v) a. 1:320 b. 1:3000 c. 1:3200 d. 1:32000
55. If 400mL of a 20% (w/v) solution are diluted to 2 Liters what will be the percentage strength
w/v? a. 8% b. 4% c.5% d. 2%
56. How many milliliters of water must be added to 250mL of a 25% (w/v) stock solution of sodium chloride to
prepare a 0.9% w/v sodium chloride solution?
a. 65100mL b. 6600mL c. 6694mL d. 6490mL
57. How many milliliters of a syrup containing 85% w/v of sucrose should be mix with 150mL of a
syrup containing 60% w/v of sucrose to make a syrup containing 80% (w/v) of sucrose?
a. 500mL b. 550mL c. 600mL d. 650mL
58. How many milliliters of 95% (w/w) sulfuric acid having a specific gravity of 1.820 should be used
in preparing 2liters of 10% (w/v) sulfuric acid?
a. 110mL b. 120mL c. 114mL d. 116mL
59. How many grams of Zinc oxide should be added to 3400grams of a 10% zinc oxide ointment to prepare
a product containing 15% of zinc oxide?
a. 150grams b. 200grams c. 250grams d. 210 grams
60. How many grams of petrolatum (diluents) should be added to 925grams of zinc oxide paste to prepare
an ointment containing 6% of coal tar?
a.59g b. 60g c. 50g d. 55g
61. Four equal amounts of belladonna extract, containing 1.15%, 1.30%, 1.35%, and 1.20% of
alkaloids respectively, were mixed. What was the percentage strength of the mixture?
a. 1.2% b. 1.4% c. 1.5% d. 1.25%
a. 5ml b. 50mL c. 0.5mL d.500mL
2. How many drops would be prescribed in each dose of a liquid medicine if 20mL contained 60 doses? The
dropper calibrates 35gtts per mL.
a. 12gtts b.15gtts c. 8gtts d. 23gtts
3. How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain 1/10
grain? a. 58mg b. 480mg c. 4800mg d. 4.8mg
4. If a pint of a certain liquid weights 9200 grains, what is the specific gravity of the
liquid? a. 1.0 b. 1.32 c. 1.276 d. 1.26
5. How many grams of dextrose are required to prepare 4500 L of a 5%
solution? a. 80,000 gb. 225,000 g c. 4 f3 d. 8 f3
6. How many grams of drug substance should be dissolved in 250 mL of water to make a 5%(w/w)
solution? a. 9.6g b.13.16g c.60 g d. 10g
7. Convert 5% to mg/mL
a. 50mg/mL b.500mg/mL c.5000mg/mL d. 5mg/mL
8. In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70% alcohol?
a. 3parts/5parts b.1part/1part c.5parts/4parts d.4parts/5parts
9. How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to prepare
1500mL of a liquid having a specific gravity of 0.925?
a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875) b.2250mL (sp.gr 0.950) 1125mL (sp gr 0.875) c.500mL
(sp.gr 0.950) 1000mL(sp gr 0.875) d. 1125mL (sp.gr 0.950) 2250mL(sp gr 0.875)
10. Zinc chloride is a three-ion electrolyte,dissociating 80% in a certain concentration. Calculate its dissociation
factor(I)
a. 2.6 b. 1.6 c. 2.9 d. 3
11. If 10mg of a drug are added to a 500mL large-volume parenteral fluid, what should be the rate of flow, in
mL/hr, to deliver 1mg of drug per hour?
a. 50mL/hr b. 20mL/hr c.500mL/hr d.5mL/hr
12. How many milliequivalents are there in 15mL of a 50% MgSO4 solution? (mol wt= 246)
a. 6.097 mEq b. 60.97 mEq c. 6.96 mEq d.69.7 mEq
13.You are directed to weigh 10g of substance so as to limit the error to 0.2%. calculate the maximum potential
error, in terms of grams, that you would not be permitted to exceed.
a. 0.05g b. 0.02g c. 0.002g d. 0.2g
14. A prescription is to taken as follows: 1 tab q.i.d. the first day; 1 tab t.i.d. the second day; 1 tab b.i.d. x 5 d;
and 1 tab q.d. thereafter. How many tablets should be dispensed to equal a 3-day supply?
a. 18 tab b. 40 tab c. 22 tab d. 47 tab
15. Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given oral
tetracycline in doses of 0.011g/lb body weight every 6 hrs. express the doses of milligrams per kilogram
of body weight.
a. 5mg/kg b.24.2mg/kg c.25mg/kg d. 11mg/kg
16. How many cochicines tablets, each containing 00mcg, may be prepared from 30g of
colchicines? a. 50,000 tab b.20,000 tab c.20 tab d.50 tab
17. Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. how many milliliters
would provide dose of 40 mcg?
a. 0.04mL b. 40mL c. 40mL d. 0.4mL
18. Nitrostat sublingual tablets are available as 1/200gr tablets. What is the approximate equivalent
in milligrams?
a. 0.325 b. 0.077 c. 0.005 d. 0.65
19. Four thousand nanograms equals 4:
a. centigrams b. grams c. milligrams d. micrograms
20. If a physician prescribed 4g of aspirin to be taken by a patient daily, about how many 5-grain tablets
should the patient take each day?
a. 10 tab b. 12 tab c.15 tab d.8 tab
,24. Pico denotes of the basic unit
a. 10 -12
b. 10 -15
c.10-18 d. 10-10
25. 1 milliliter is 1000x greater than:
a. microliter b.picoliter c.nanoliter d.liter
26. Sudafed cough syrup contains 0.0g of dextromethorphan hydrobromide in each fluidounce. How many
milligrams of this agent would be present in each teaspoonful dose?
a. 10mg b. 12mg c. 15mg d. 20mg
27. The usual dose of digoxin for rapid digitalization is a total of 1.0mg, divide into two or more portion at
intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50mcg/mL would provide this
dose?
a. 15mL b. 10mL c.25mL d.20mL
28. The dose of beclamethasone, an aerosolized inhalant, is 200mcg twice daily. The commercial inhaler
delivers 50mcg per metered inhalation and contains 200 inhalations. How many inhalers should be dispensed to
a patient if a 60-day supply is prescribed?
a. 3 b.2 c. 4 d.5
29. If a physician prescribed Keflex, 250mg q.i.d. x 10 days, how many milliliters of keflex
suspension containing 250mg per 5 mL should be dispensed?
a. 250mL b.200mL c. 150mL d.100mL
30. Terpin hydrate and codeine elixir contains 60mg of codeine per 30mL. how much additional codeine should
be added to 180mL of the elixir so that each teaspoonful will contain 15mg of codeine?
a. 180mg b.200mg c.170mg d.190mg
31. The directions intended for the patient on a prescription read 1tbsp a.c. and h.s. for 10days. What is the
minimum volume the pharmacist should dispense?
a. 200mL b. 150mL c. 600mL d. 450mL
32. If the cost of human growth hormone is P40/mg q4h six times daily. How many will a 180lb patient
receive daily?
a. 12mg b. 164mg c.650mg d.980mg
33. The pediatric dose of cefadroxil is 30mg/kg/day. If a child was given a daily dose of 2 teaspoonfuls of
pediatric suspension containing 125mg of cefadroxil per 5mL, what was the weight, in pounds of the
child?
a. 19lbs b. 17.3lbs c. 18.3lbs d. 18.5lbs
34. A ferrous sulfate syrup contains 220mg of FeSO4.7H2O per teaspoon dose. How many milligrams of
elemental iron are present in the dose? (mol wt FeSO4.7H2O= 278; at wt of Fe=55.9, S=32.1, O=16, H=1.0)
a. 44mg b. 50mg c. 88mg d. 100mg
35. An antacid tablet contains 80mg of dried aluminum hydroxide gel and 20g of magnesium trisilicate. How
many kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product, each
containing 100 tablets?
a.2000kg b.20000kg c.200kg d.8000kg
36. An estradiol transdermal system contains in each skin patch 4mg of estradiol and 0.3mL of alcohol.
How many liters of alcohol would be required to manufacture a half-million patches?
a. 15L b. 150L c. 1500L d. 300L
37. From the ff formula:
Benzyl benzoate 250mL
Triethanolamine 5mL
Purified water, to make 1000mL
Calculate the quantity of benzyl benzoate required to make 6fl.Oz of benzyl benzoate lotion
a.45mL b. 40mL c. 4.5mL d. 25mL
38. If 150mL of polyethylene glycol 400 weighs 74.1g, what is its specific
gravity? a. 0.88 b. 0.494 c. 2.35 d. 1.3
39. A sunscreen lotion contains 5g of methyl salicylate (sp gr 1.045) per 1000mL. how many milliliters
of methyl salicylate should be used in preparing 1gallon of the lotion?
a. 189.25mL b. 197.77mL c. 181.10mL d. 190mL
40. Cocoa butter, which is solid at room temperature and melts at 34°C, has a specific gravity of 0.86. If a
, 43. If an intravenous dose of mannitol is 1.5% (w/v) sodium chloride solution can be made from 1 lb of sodium
chloride?
a. 50,444 mL b. 30,000 mL c. 50, 400 mL d. 1,000 mL
44. If 10mL of a nitroglycerin injection (5mg of nitroglycerin per milliliter) are added to make a liter of
intravenous fluid, what is the percentage (w/v) of nitroglycerin in the final product?
a. 0.025% b. 0.05% c. 0.005% d. 0.0005%
45. How many milliliters of resorcinol monoacetate should be used to prepare 1 pint of a 15% (v/v) lotion?
a. 71mL b. 65 mL c. 76 mL d. 69 mL
46. How many liters of a mouthwash can be prepared from 100mL of cinnamon flavor if its concentration is
to be 0.5% (v/v)?
a. 10L b. 20L c. 15L d. 18 L
47. One pound of a fungicidal ointment contains 9.08g of undecylenic acid. Calculate the percentage (w/w)
of undecylenic acid in the ointment.
a. 1.81% b. 1.5% c. 2% d. 2.5%
48. A vaginal foam contains 0.01% (w/v) of dienestrol. Express this concentration as a ration strength.
a. 1:100 b. 1:1,000 c. 1:1,000,000,000 d. 1:10,000
49. A sample of white petrolatum contains 10mg of tocopherol per kilogram as a preservative. Express
the amount of tocopherol as a ratio strength.
a. 1:100,000 b. 1:1,000 c. 1:1,000,000 d. 1:10,000
50. Hepatitis B immune globulin is preserved with 1:10,000 w/v of thimerosal. If the dose of the injection is
0.06 mL/Kg of body weight, how many micrograms of thimerosal would be contained in the dose for a 150-lb
patient?
a. 400mcg b. 409mcg c. 415 mcg d. 450mcg
51. What is the percent concentration of cholesterol in a patient’s blood serum if the cholesterol level is
determined to be 260mg %?
a. 2.6% b. 26% c. 0.26% d. 0.026%
52. If a serum sample is determined to contain 270mg/dL of cholesterol, what is the concentration of
cholesterol (mol wt 386) in terms of millimoles per liter?
a. 6.5mmol/L b. 6.9mmol/L c. 69.9mmol/L d. 5.66mmol/L
53. A glucose meter shows that a patient’s blood contains 125mg% of glucose. Express this value as
mg/mL. a. 1.25mg/mL b. 12.5mg/mL c. 125mg/mL d. 0.125mg/mL
54. If 250mL of a 1:800 (v/v) solution are diluted to 1000mL, what will be the ration strength
(v/v) a. 1:320 b. 1:3000 c. 1:3200 d. 1:32000
55. If 400mL of a 20% (w/v) solution are diluted to 2 Liters what will be the percentage strength
w/v? a. 8% b. 4% c.5% d. 2%
56. How many milliliters of water must be added to 250mL of a 25% (w/v) stock solution of sodium chloride to
prepare a 0.9% w/v sodium chloride solution?
a. 65100mL b. 6600mL c. 6694mL d. 6490mL
57. How many milliliters of a syrup containing 85% w/v of sucrose should be mix with 150mL of a
syrup containing 60% w/v of sucrose to make a syrup containing 80% (w/v) of sucrose?
a. 500mL b. 550mL c. 600mL d. 650mL
58. How many milliliters of 95% (w/w) sulfuric acid having a specific gravity of 1.820 should be used
in preparing 2liters of 10% (w/v) sulfuric acid?
a. 110mL b. 120mL c. 114mL d. 116mL
59. How many grams of Zinc oxide should be added to 3400grams of a 10% zinc oxide ointment to prepare
a product containing 15% of zinc oxide?
a. 150grams b. 200grams c. 250grams d. 210 grams
60. How many grams of petrolatum (diluents) should be added to 925grams of zinc oxide paste to prepare
an ointment containing 6% of coal tar?
a.59g b. 60g c. 50g d. 55g
61. Four equal amounts of belladonna extract, containing 1.15%, 1.30%, 1.35%, and 1.20% of
alkaloids respectively, were mixed. What was the percentage strength of the mixture?
a. 1.2% b. 1.4% c. 1.5% d. 1.25%
