AGNP BOARD EXAM QUESTIONS EYE EAR
NOSE THROAT PRESCRIPTION (102
QUESTIONS WITH ANSWERS AND
EXPLANATIONS)
Question:1
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis, should be
administered:
a) with milk.
b) with meals.
c) on an empty stomach. Correct
d) with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1 hour prior to,
or 2 hours after meals) to increase total absorption and with adequate amount of fluid to
reduce the risk of esophageal irritation and ulceration. It should be administered at least 1
to 2 hours prior to, or 4 hours after, an antacid containing aluminum and magnesium
cations. It may chelate with tetracycline (Sumycin) and reduce its total absorption. Serum
concentrations may be decreased if taken with dairy products.
Question:2
The brand name for sulfacetamide ophthalmic is:
a) AzaSite.
b) Bleph-10. Correct
c) Besivance.
d) Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the brand name of
azithromycin. Besifloxacin is the generic name for Besivance. The generic name of
Garamycin is gentamicin sulfate.
Question:3
The generic name for Polytrim ophthalmic is:
a) trimethoprim and polymyxin B. Correct
, b) bacitracin/polymyxin B.
c) azithromycin.
d) besifloxacin.
Explanation:
The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is the brand name
for bacitracin/polymyxin B. The brand name for azithromycin is AzaSite. Besifloxacin brand
name is Besivance.
Question:4
Which of the following does NOT cause a drug-disease interaction when using a
decongestant/antihistamine medication such as Naphazoline/pheniramine (Naphcon-A)?
a) Cardiovascular disease
b) Angle-closure glaucoma
c) Prostatic hypertrophy
d) Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-A) include
angle-closure glaucoma, MAOI inhibitor use within 14 days, cardiovascular disease,
hypertension, diabetes mellitus, prostatic hypertrophy and urinary tract obstruction.
Question:5
The maximum daily dose of acetaminophen for ages 12 years and older is:
a) 1200 milligrams/day.
b) 2000 milligrams/day.
c) 3000 milligrams/day.
d) 4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause liver damage.
Doses of 4000 mg (4 grams) per day should not be exceeded in patients 12 years and older.
Maximum dose in neonates is 60 mg/kg/day and 75 mg/kg/day in infants and children.
Question:6
For treatment of blepharitis, patients should be instructed to apply erythromycin ointment
to the affected eye using:
, a) a 0.5 inch ribbon 3 times daily for 5 days.
b) a 0.5 cm ribbon 3 times daily for 5 days.
c) a 1-inch ribbon 5 times daily for 7 days.
d) a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin ophthalmic ointment
up to 6 times daily for up to 10 days.
Question:7
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is indicated in
the treatment of:
a) acute conjunctivitis.
b) vernal conjunctivitis. Correct
c) fungal keratitis.
d) herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control allergic conditions.
It is indicated in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and
vernal keratitis. Vernal conjunctivitis is long-term inflammation of the outer lining of the
eyes. It is due to an allergic reaction.
Question:8
The most effective treatment for eradication of group A streptococcus in those who are
apparent carriers is:
a) a single dose of intramuscular penicillin (Bicillin).
b) oral rifampin (Rifadin) for 4 days.
c) oral clindamycin (Cleocin) for 10 days. Correct
d) a single dose of intramuscular ceftriaxone (Rocephin).
Explanation:
The most effective treatment for eradication of group A streptococcus in those who are
carriers is oral clindamycin (Cleocin) for 10 days. A single dose of intramuscular penicillin
(Bicillin) plus 4 days of oral rifampin (Rifadin) is also effective.
Question:9
, The generic name for Dramamine is:
a) doxylamine.
b) diphenhydramine.
c) brompheniramine.
d) dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
Question:10
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS) who are
allergic to penicillin, the best alternative first-line therapy is:
a) azithromycin (Zithromax).
b) clarithromycin (Biaxin).
c) doxycycline (Vibramycin). Correct
d) metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable alternative
for first-line therapy and can be used in patients with penicillin allergy. A respiratory
fluoroquinolone (levofloxacin 500 mg orally or moxifloxacin 400 mg orally once daily) is
another alternative for penicillin-allergic patients. However, fluoroquinolones should be
reserved for those who have no alternative treatment options, because the serious adverse
effects associated with fluoroquinolones generally outweigh the benefits for patients with
acute sinusitis. Macrolides (clarithromycin or azithromycin), trimethoprim-
sulfamethoxazole, and second- or third-generation cephalosporins are not recommended
for empiric therapy because of high resistance rates of S. pneumoniae.
Question:12
Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is
administered orally:
a) based on weight twice daily for 5 days.
b) 75 mg daily x 5 days.
c) 75 mg twice daily x 5 days. Correct
d) 75 mg twice daily x 10 days.
Explanation:
NOSE THROAT PRESCRIPTION (102
QUESTIONS WITH ANSWERS AND
EXPLANATIONS)
Question:1
Oral tetracycline (Sumycin), for the treatment of acute frontal sinusitis, should be
administered:
a) with milk.
b) with meals.
c) on an empty stomach. Correct
d) with an antacid.
Explanation:
Tetracycline (Sumycin) should be administered on an empty stomach (i.e., 1 hour prior to,
or 2 hours after meals) to increase total absorption and with adequate amount of fluid to
reduce the risk of esophageal irritation and ulceration. It should be administered at least 1
to 2 hours prior to, or 4 hours after, an antacid containing aluminum and magnesium
cations. It may chelate with tetracycline (Sumycin) and reduce its total absorption. Serum
concentrations may be decreased if taken with dairy products.
Question:2
The brand name for sulfacetamide ophthalmic is:
a) AzaSite.
b) Bleph-10. Correct
c) Besivance.
d) Garamycin.
Explanation:
The brand name of sulfacetamide ophthalmic is Bleph-10. AzaSite is the brand name of
azithromycin. Besifloxacin is the generic name for Besivance. The generic name of
Garamycin is gentamicin sulfate.
Question:3
The generic name for Polytrim ophthalmic is:
a) trimethoprim and polymyxin B. Correct
, b) bacitracin/polymyxin B.
c) azithromycin.
d) besifloxacin.
Explanation:
The generic name for Polytrim is trimethoprim and polymyxin B. Polycin is the brand name
for bacitracin/polymyxin B. The brand name for azithromycin is AzaSite. Besifloxacin brand
name is Besivance.
Question:4
Which of the following does NOT cause a drug-disease interaction when using a
decongestant/antihistamine medication such as Naphazoline/pheniramine (Naphcon-A)?
a) Cardiovascular disease
b) Angle-closure glaucoma
c) Prostatic hypertrophy
d) Hypothyroidism Correct
Explanation:
Contraindications/cautions when using naphazoline/pheniramine (Naphcon-A) include
angle-closure glaucoma, MAOI inhibitor use within 14 days, cardiovascular disease,
hypertension, diabetes mellitus, prostatic hypertrophy and urinary tract obstruction.
Question:5
The maximum daily dose of acetaminophen for ages 12 years and older is:
a) 1200 milligrams/day.
b) 2000 milligrams/day.
c) 3000 milligrams/day.
d) 4000 milligrams/day. Correct
Explanation:
Acetaminophen generally is safe to use. In high doses, however, it can cause liver damage.
Doses of 4000 mg (4 grams) per day should not be exceeded in patients 12 years and older.
Maximum dose in neonates is 60 mg/kg/day and 75 mg/kg/day in infants and children.
Question:6
For treatment of blepharitis, patients should be instructed to apply erythromycin ointment
to the affected eye using:
, a) a 0.5 inch ribbon 3 times daily for 5 days.
b) a 0.5 cm ribbon 3 times daily for 5 days.
c) a 1-inch ribbon 5 times daily for 7 days.
d) a 1-cm ribbon 5 times daily for 7 days. Correct
Explanation:
Patients should be instructed to apply a 1-cm ribbon of erythromycin ophthalmic ointment
up to 6 times daily for up to 10 days.
Question:7
Ophthalmic cromolyn inhibits the degranulation of sensitized mast cells. It is indicated in
the treatment of:
a) acute conjunctivitis.
b) vernal conjunctivitis. Correct
c) fungal keratitis.
d) herpes keratoconjunctivitis.
Explanation:
Ophthalmic cromolyn is a mast cell stabilizer used to prevent or control allergic conditions.
It is indicated in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and
vernal keratitis. Vernal conjunctivitis is long-term inflammation of the outer lining of the
eyes. It is due to an allergic reaction.
Question:8
The most effective treatment for eradication of group A streptococcus in those who are
apparent carriers is:
a) a single dose of intramuscular penicillin (Bicillin).
b) oral rifampin (Rifadin) for 4 days.
c) oral clindamycin (Cleocin) for 10 days. Correct
d) a single dose of intramuscular ceftriaxone (Rocephin).
Explanation:
The most effective treatment for eradication of group A streptococcus in those who are
carriers is oral clindamycin (Cleocin) for 10 days. A single dose of intramuscular penicillin
(Bicillin) plus 4 days of oral rifampin (Rifadin) is also effective.
Question:9
, The generic name for Dramamine is:
a) doxylamine.
b) diphenhydramine.
c) brompheniramine.
d) dimenhydrinate. Correct
Explanation:
The generic name of Dramamine is dimenhydrinate.
Question:10
For empiric treatment of patients with acute bacterial rhinosinusitis (ABRS) who are
allergic to penicillin, the best alternative first-line therapy is:
a) azithromycin (Zithromax).
b) clarithromycin (Biaxin).
c) doxycycline (Vibramycin). Correct
d) metronidazole (Flagyl).
Explanation:
Doxycycline (100 mg orally twice daily or 200 mg orally daily) is a reasonable alternative
for first-line therapy and can be used in patients with penicillin allergy. A respiratory
fluoroquinolone (levofloxacin 500 mg orally or moxifloxacin 400 mg orally once daily) is
another alternative for penicillin-allergic patients. However, fluoroquinolones should be
reserved for those who have no alternative treatment options, because the serious adverse
effects associated with fluoroquinolones generally outweigh the benefits for patients with
acute sinusitis. Macrolides (clarithromycin or azithromycin), trimethoprim-
sulfamethoxazole, and second- or third-generation cephalosporins are not recommended
for empiric therapy because of high resistance rates of S. pneumoniae.
Question:12
Dosing of oseltamivir (Tamiflu) for adults and adolescents with active influenza is
administered orally:
a) based on weight twice daily for 5 days.
b) 75 mg daily x 5 days.
c) 75 mg twice daily x 5 days. Correct
d) 75 mg twice daily x 10 days.
Explanation:
