Molecular Epidemiology of Infectious Diseases Exam Review 2023

Molecular Epidemiology of Infectious Diseases Exam Review 2023 Molecular Epidemiology - The application of the techniques of molecular biology to the study of the epidemiology of disease in human populations Molecular Epidemiology - Development of molecular tools, genotyping and gene expression Incorporation of concepts and results of populations genetics of infectious diseases Integration of recent advances in theoretical epi, modeling, and evolutionary ecology of diseases Better understanding of transmission for the development of risk factors analyses Microbiologic Classification - Viruses, Bacteria, Fungi, and Parsites & their specific characteristics Influenza Virus - Fout types: influenza A, B, C, and D Only types A and B cause outbreaks and only A is known to cause pandemics Influenza Virus subtypes - Hemagglutinin (H) subtype Neuraminidase (N) subtype Malaria - Parasite Types of Tests - Microscopy, Culture, Immunologic, Antigen Testing, Antibody Testing, Nucleic acid-based identification methods (PCR, PFGE, Whole Genome Sequencing) Microscopy - Staining (Gram stain, acid-fast stains, fluorescent stains) Can be done quickly but accuracy can vary based on skills of microscopist and equipment Culture - Advantages - Gold standard Specific....