WGU D115 Unit 5 Questions and
Answers with Certified Solutions
Which two processes are involved in platelet activation?
Cyclooxygenase-1 (COX-1) inactivation
Aggregation
Adhesion ✔✔Platelet activation involves three linked processes: (1) adhesion, (2) activation, and
(3) aggregation. Platelet activation stimuli include epinephrine, thrombin, and collagen.
Select four common causes of anemia from the list below.
Increased red cell destruction
Chronic blood loss
Severe bleeding
Impaired erythrocyte production
Blood transfusion ✔✔Impaired production of erythrocytes, increased red cell destruction, severe
bleeding, and chronic blood loss can cause anemia.
explain why the nurse practitioner should ask the patient about her paresthesias and ataxia.
✔✔Without the presence of intrinsic factor, vitamin B12 will not be absorbed effectively from
the gastrointestinal tract.
,Describe what causes pernicious anemia. ✔✔Pernicious anemia is caused by vitamin B12
deficiency, which is often associated with the end stage of type A chronic atrophic (autoimmune)
gastritis. Autoimmune gastritis impairs the production of IF, which is required for vitamin B12
uptake from the gut.
Select three possible causes of lymphadenopathy from the options below.
Inflammatory condition
Lipid storage disease
Neoplastic disease
Cardiac disease
Peripheral vascular dysfunction ✔✔There are multiple causes of lymphadenopathy. It may be
caused by neoplastic disease, so all lymphadenopathies must be closely followed and evaluated.
Lymphadenopathy may also be caused by an immunologic or inflammatory condition and by
lipid storage disease; this type of lymphadenopathy is usually widespread, including the liver and
spleen.
What is the most common cause of iron deficiency anemia (IDA) in children during the first few
years of life?
Dietary insufficiencies
, Absorption problems
Blood loss
Increased iron requirement ✔✔Insufficient dietary iron is the most common cause of IDA in
children during the first few years of life.
Which stressor triggers sickling?
Increased plasma volume
Increased oxygen tension of the blood
Decreased plasma osmolality
Low temperature ✔✔Low temperature causes vasoconstriction, slowing blood flow, leading to
RBC deoxygenation, which triggers sickling.
cause of ITP ✔✔In 70% of ITP cases, there is an antecedent viral disease that stimulates
production of antiplatelet antibodies that bind to the plasma membranes of platelets, causing
platelet sequestration and destruction by phagocytes in the spleen and other lymphoid tissues at a
rate that exceeds the ability of the bone marrow to produce them.
Answers with Certified Solutions
Which two processes are involved in platelet activation?
Cyclooxygenase-1 (COX-1) inactivation
Aggregation
Adhesion ✔✔Platelet activation involves three linked processes: (1) adhesion, (2) activation, and
(3) aggregation. Platelet activation stimuli include epinephrine, thrombin, and collagen.
Select four common causes of anemia from the list below.
Increased red cell destruction
Chronic blood loss
Severe bleeding
Impaired erythrocyte production
Blood transfusion ✔✔Impaired production of erythrocytes, increased red cell destruction, severe
bleeding, and chronic blood loss can cause anemia.
explain why the nurse practitioner should ask the patient about her paresthesias and ataxia.
✔✔Without the presence of intrinsic factor, vitamin B12 will not be absorbed effectively from
the gastrointestinal tract.
,Describe what causes pernicious anemia. ✔✔Pernicious anemia is caused by vitamin B12
deficiency, which is often associated with the end stage of type A chronic atrophic (autoimmune)
gastritis. Autoimmune gastritis impairs the production of IF, which is required for vitamin B12
uptake from the gut.
Select three possible causes of lymphadenopathy from the options below.
Inflammatory condition
Lipid storage disease
Neoplastic disease
Cardiac disease
Peripheral vascular dysfunction ✔✔There are multiple causes of lymphadenopathy. It may be
caused by neoplastic disease, so all lymphadenopathies must be closely followed and evaluated.
Lymphadenopathy may also be caused by an immunologic or inflammatory condition and by
lipid storage disease; this type of lymphadenopathy is usually widespread, including the liver and
spleen.
What is the most common cause of iron deficiency anemia (IDA) in children during the first few
years of life?
Dietary insufficiencies
, Absorption problems
Blood loss
Increased iron requirement ✔✔Insufficient dietary iron is the most common cause of IDA in
children during the first few years of life.
Which stressor triggers sickling?
Increased plasma volume
Increased oxygen tension of the blood
Decreased plasma osmolality
Low temperature ✔✔Low temperature causes vasoconstriction, slowing blood flow, leading to
RBC deoxygenation, which triggers sickling.
cause of ITP ✔✔In 70% of ITP cases, there is an antecedent viral disease that stimulates
production of antiplatelet antibodies that bind to the plasma membranes of platelets, causing
platelet sequestration and destruction by phagocytes in the spleen and other lymphoid tissues at a
rate that exceeds the ability of the bone marrow to produce them.
