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OCR A-Level Biology Non-Specific Disease Summary

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A HandWritten summary which contains all the necessary A* Content for Non-Specific Disease at OCR A-Level Biology.

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Physical Defences :
·
Callose: B
glucose polymer that is
deposited in cell walls , spaces
and plasmodesmata
↳ Prevents
pathogen entry
Chemical Defences :



↳ Insect
Repellant insectisides , ,
antibacterial/fungal components anti-comecyte enzymes
, ,
toxins




Barriers The :
skin , mucous membranes ,
lysozymes in tears/urine ,
Stomach acid
Blood
Clotting
:

forms a barrier and prevents blood loss

:Platelets activated by damaged tissue produces thromboplastin
2 .



Thromoplastin Catalyses prothrombin turning into thrombin
3
Thrombin
Catalyses fibrinogen turning into fibrin
.




- 4
[collagen fibers) are deposited forming a clot
.
Fibrin ,




- Inflammatory Response :




Damaged mast cens produce histamines and cytokines
.


2 Histamines cause vasodilation the temperature raises
so prevents pathogens reproducing
.




3 .

Histamines mane vessels more lealy forming more tissue fluid
4 blood
phagocytes / white
Cytokines ceus attract
.




-


pathogens and give optimum conditions for the specific immune system
Fevers Kill :




Phagocytosis Specialised white blood ceus engulf and destroy pathogens
.
:




1 .


Phagocyte attracted to the
pathogen by cytokines
2
Phagocyte foreign pathogen binds to the
.




.
3
I Phagocyte engulfs the
pathogen forming a phagosome
4
E Phagosome combines with
lysosome forming a phagolysosome a

S
break down the
Digestive enzymes
pathogens leaving the antigens
.




E Antigens combine with MHC in cytoplasm to form on MHC- antigen complex
6 .




complex is displayed making an antigen-presenting cen
7 MAC .




Opsonins Bind to pathogens for easier recognition by phagocytes
:




Natural
Immunity Occurs Naturally in the body
:




Natural Active Antibody Production Natural Passive : :
Antibodies passed along in breast milk

Artificial Immunity Provided by disease
medical science
against deadly
:




Artificial Active Vaccination with an inactive
pathogen Artificial passive Antibody injection
: :

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Written in
2023/2024
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Course Summaries by Faith

Handwritten A-Level notes by an Oxford University Medical Student that specifically target the content needed for an A-A*.

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