Gastrointestinal Agents
The agents which help intreating the problems
related to gastrointestinal tract.
ACIDIFIERS:
A) Acidifying agent
B) Dilute HCI
C) Antacids - Magnesium hydroxide, Sodium
bicarbonate, Combination of Antacids.
CATHARTICS:
A) Magnesium sulfate
B)Sodium Orthophosphate
) Bentonite
PROTECTIVE AND ADSORBENTS:-Used to treat
Diarrhoea E.g. Kaolin
ACIDIFYING AGENTS (ACIDIFIERS) E.g. Dilute
HCI
Properties and causes
Those are used to treat" achlorhydria " [absence
of HCI in stomach ] and Hypochlorhydria ( less
HClin the stomach). Gastric HCI Performs
following functions:
1. It kills the bacteria ingested with food and
drinks
2. It softenthe food materials
3. It promotes the formation of" proteolytic
enzyme'" i.e. pepsin which is formed from
pepsinogen when the pH of gastric contents
is below6.
, 4. Deficiency of HCl causes gastrointestinal
disturbances including mild Diarrhoea,
epigastric pain and sensitivity to spicy food.
5. Dil. HClthen further diluted is used as an
acidifying agent.
HCI
It is asituation of hydrogen chloride gas in water.
Dilute HCI contains 9.5 to 10.5% w/w HCI(at least
9.5g to 10.5g HCl in 100g HCI) NOTE :- Assay is
done to check how much compound is present
It is prepared by diluting conc. HCI when dilute
HCl is further diluted with 25-50volumes of
water, it may be used as an " acidifying agent
PREPARATION
1. From sodium chloride (NaCl)
HCl is prepared by treating conc. H,SO4 with
NaCl.
NaCl + H,SO, HCI + NaHSO, (sodium hydrogen
sulphate)
NaHSO, +NaCl HCl + Na,sO4
Sodium hydrogen sulphate is reacted further
with more quantity of NaCl to obtain more
supplies of HCI. The acid so obtained may contain
impurities like Sulphuric acid, arsenic acid,
chlorine etc. The treatment is done to remove
these impurities for E.g. BaCl,( Barium chloride)
i d h , fr
The agents which help intreating the problems
related to gastrointestinal tract.
ACIDIFIERS:
A) Acidifying agent
B) Dilute HCI
C) Antacids - Magnesium hydroxide, Sodium
bicarbonate, Combination of Antacids.
CATHARTICS:
A) Magnesium sulfate
B)Sodium Orthophosphate
) Bentonite
PROTECTIVE AND ADSORBENTS:-Used to treat
Diarrhoea E.g. Kaolin
ACIDIFYING AGENTS (ACIDIFIERS) E.g. Dilute
HCI
Properties and causes
Those are used to treat" achlorhydria " [absence
of HCI in stomach ] and Hypochlorhydria ( less
HClin the stomach). Gastric HCI Performs
following functions:
1. It kills the bacteria ingested with food and
drinks
2. It softenthe food materials
3. It promotes the formation of" proteolytic
enzyme'" i.e. pepsin which is formed from
pepsinogen when the pH of gastric contents
is below6.
, 4. Deficiency of HCl causes gastrointestinal
disturbances including mild Diarrhoea,
epigastric pain and sensitivity to spicy food.
5. Dil. HClthen further diluted is used as an
acidifying agent.
HCI
It is asituation of hydrogen chloride gas in water.
Dilute HCI contains 9.5 to 10.5% w/w HCI(at least
9.5g to 10.5g HCl in 100g HCI) NOTE :- Assay is
done to check how much compound is present
It is prepared by diluting conc. HCI when dilute
HCl is further diluted with 25-50volumes of
water, it may be used as an " acidifying agent
PREPARATION
1. From sodium chloride (NaCl)
HCl is prepared by treating conc. H,SO4 with
NaCl.
NaCl + H,SO, HCI + NaHSO, (sodium hydrogen
sulphate)
NaHSO, +NaCl HCl + Na,sO4
Sodium hydrogen sulphate is reacted further
with more quantity of NaCl to obtain more
supplies of HCI. The acid so obtained may contain
impurities like Sulphuric acid, arsenic acid,
chlorine etc. The treatment is done to remove
these impurities for E.g. BaCl,( Barium chloride)
i d h , fr
