SONiCeS
- ROBBINS
-> RUBINS
->
Dr .
Najeeb
-> OSMOSiS
, VASCULITIS
->
Inflammation of Blood Vessels
->
constitutional signs and symptoms
L
1
SYSTEMIC EFFECTS LDCAL EFFECTS
1 AORTA (E12stic Artery)
inflammation
.
BU ↳ functionlesiz (Cardinal Sign) .
Yophilic recuritment - You * n
↳ NO PULSE
Ment
,
Chemokines 2. Muscular Arteries
TNF-X TNF-U , ,
11-1 smalles lumen->Thrombosis - occlusion
P
⑰
Infracts
Thermostat Osmostat Hypothalamus ↓
↳ FEVER
E
,
L ORGAN ISCHEMIA
3 .
Arterioles -> Capillaries -> microhemorrhage
↓
PURPURA
B .
MALAISE -> restlessness ,
lethargy
->
IL-1
&TyrosiKinase
S
& -- XTNFA
ne Il-1 TNF-A
->
, leukocytochastic Vasculitis
- IL-1
Acute Phase Reactants - C-reactive
> proteins -> ↑ESR
Indicator of orgoing
damage and inflammation
- ROBBINS
-> RUBINS
->
Dr .
Najeeb
-> OSMOSiS
, VASCULITIS
->
Inflammation of Blood Vessels
->
constitutional signs and symptoms
L
1
SYSTEMIC EFFECTS LDCAL EFFECTS
1 AORTA (E12stic Artery)
inflammation
.
BU ↳ functionlesiz (Cardinal Sign) .
Yophilic recuritment - You * n
↳ NO PULSE
Ment
,
Chemokines 2. Muscular Arteries
TNF-X TNF-U , ,
11-1 smalles lumen->Thrombosis - occlusion
P
⑰
Infracts
Thermostat Osmostat Hypothalamus ↓
↳ FEVER
E
,
L ORGAN ISCHEMIA
3 .
Arterioles -> Capillaries -> microhemorrhage
↓
PURPURA
B .
MALAISE -> restlessness ,
lethargy
->
IL-1
&TyrosiKinase
S
& -- XTNFA
ne Il-1 TNF-A
->
, leukocytochastic Vasculitis
- IL-1
Acute Phase Reactants - C-reactive
> proteins -> ↑ESR
Indicator of orgoing
damage and inflammation