NSG 533 ADV PHARM: MODULE 1: GI: CHP 17 2023 VERIFIED QUESTIONS AND ANSWERS ALREADY PASSED

Which drug class is most effective in treating erosive lesions:? - CORRECT ANS PPIs Name 4 H2RAs: - CORRECT ANS Cimetidine (Tagamet) Famotidine (Pepcid) Ranitidine (Zantac) Nizatidine (Axid) What is the action of H2RAs? - CORRECT ANS Decrease acid secretion by blocking histamine 2-receptors in gastric parietal cells Name 4 benefits of H2RAs - CORRECT ANS 1. Relieve GERD symptoms 2. Can be administered prophylactically 3. More effective at controlling chronic GERD symptoms than ANTACIDS 4. Intermittent & routine dosing possible based on degree of symptom control needed. Name 2 drawbacks of H2RAs - CORRECT ANS 1. Less effective in controlling chronic GERD symptoms than PPIs 2. Renal elimination may require dose adjustment in kidney dysfunction patients What are the side effects associated with H2RAs? - CORRECT ANS H/A, nausea (Cimetidine), weak inhibitor, common drug interactions, gynecomastia, & Vit B-12 deficiency which affects patients' tolerance Name the benefits of Antacids - CORRECT ANS 1. Useful for intermittent treatment of GERD symptoms 2. Immediate symptom relief