Pharmacology ATI Proctored NEW 2023 LATEST UPDATE GRADED A+

Benzodiazepines - ANSWER Includes "Pams" Alprazolam, diazepam, lorazepam, oxazepam, clonazepam, chlordiazepoxide, chlorazepate Enhances GABA: increased GABA means decreased neuron activity Treats anxiety, PTSD, seizures, alcohol withdrawal, muscle spasm, induction of anesthesia Usually short term; if long term do NOT stop abruptly Antidote is flumazenil Side effects: CNS depression - sedation and respiratory depression, amnesia, dependency, and withdrawal effects Atypical anxiolytic - ANSWER Buspirone Can take 2-6 weeks to work, but can be long term! Treats panic disorder, anxiety, OCD, and PTSD Side effects: dizziness, nausea (take w/ food to relieve), headache (sedation and dependency is not seen like in benzo) Trick to remember difference between Benzodiazepine and buspirone - ANSWER "Pam" has anxiety, so she goes on a "benzo" and takes it for a long time but realizes that it is not healthy. So she takes a "bus" to a "pier" to sit "alone" and decides to treat her anxiety long term with "buspirone" Selective Serotonin Reuptake Inhibitors (SSRIs) - ANSWER Usually end in "ine": paroxetine, sertraline, citalopram, escitalopram, fluoxetine, fluvoxamine Inhibits serotonin reuptake" increases serotonin