NR 546 EXAM WEEK QUESTIONS AND CORRECT DETAILED
ANSWERS
How do neurotransmitters work? - ANSWER-Once it crosses the
gap, it is taken up by the post-synaptic receptor, i.e. the
dendrite of the next neuron.
The chemical message is converted back into an electrical
impulse and the process of transmission begins again.
Each one has its own specific molecular structure that fits
perfectly into a post-synaptic receptor site, like a lock and
key.
Why do neurotransmitters work with receptors in the brain -
ANSWER-to influence and regulate a range of processes,
including emotions and mental performance
Behavioral symptoms are related to - ANSWER-malfunctioning
neurons
The symptoms may be relieved, worsened, or produced by
drugs such as psychotropic medications that alter
neurotransmitter processes and functioning
What are synapses? - ANSWER-Synapses are where neurons
communicate with their target cells
Where are drugs ingested? - ANSWER-mouth (orally)
What is cytochrome P450? - ANSWER-Cytochrome P450
(CYP450) enzymes are essential for the metabolism of many
medications.
What is phase 1 metabolism? - ANSWER-Oxidation (most
common), reduction, hydrolysis
How many outcomes of phase 1 metabolism do we have -
ANSWER-3
, NR 546 EXAM WEEK QUESTIONS AND CORRECT DETAILED
ANSWERS
What is the first outcomes of phase 1 metabolism - ANSWER-
drugs become completely inactive
What is the second outcomes of phase 1 metabolism - ANSWER-
drugs become partially inactive but one or more metabolites
remain active
What is the third outcomes of phase 1 metabolism - ANSWER-
the original drug is not pharmacologically active but one
metabolite remains active
Inhibitors are - ANSWER-drugs that decrease medication
metabolism
What are inhibitors? - ANSWER-Inhibitors are compounds
(many of which are drugs) that inhibit the activity of the
enzyme. Enzyme inhibition result in less drug metabolism.
The drug serum level (and therapeutic effect) will increase.
This can result in drug toxicity.
Which neurotransmitter(s) may be responsible for a client's
symptoms of depression? Select all that apply. - ANSWER-
increased levels of acetylcholine
Correct answer.
decreased levels of norepinephrine
Correct answer.
decreased levels of histamine
Correct answer.
decreased levels of glutamate
Drug metabolism is influenced by which factors - ANSWER-age,
smoking, caffeine intake, or other medications
ANSWERS
How do neurotransmitters work? - ANSWER-Once it crosses the
gap, it is taken up by the post-synaptic receptor, i.e. the
dendrite of the next neuron.
The chemical message is converted back into an electrical
impulse and the process of transmission begins again.
Each one has its own specific molecular structure that fits
perfectly into a post-synaptic receptor site, like a lock and
key.
Why do neurotransmitters work with receptors in the brain -
ANSWER-to influence and regulate a range of processes,
including emotions and mental performance
Behavioral symptoms are related to - ANSWER-malfunctioning
neurons
The symptoms may be relieved, worsened, or produced by
drugs such as psychotropic medications that alter
neurotransmitter processes and functioning
What are synapses? - ANSWER-Synapses are where neurons
communicate with their target cells
Where are drugs ingested? - ANSWER-mouth (orally)
What is cytochrome P450? - ANSWER-Cytochrome P450
(CYP450) enzymes are essential for the metabolism of many
medications.
What is phase 1 metabolism? - ANSWER-Oxidation (most
common), reduction, hydrolysis
How many outcomes of phase 1 metabolism do we have -
ANSWER-3
, NR 546 EXAM WEEK QUESTIONS AND CORRECT DETAILED
ANSWERS
What is the first outcomes of phase 1 metabolism - ANSWER-
drugs become completely inactive
What is the second outcomes of phase 1 metabolism - ANSWER-
drugs become partially inactive but one or more metabolites
remain active
What is the third outcomes of phase 1 metabolism - ANSWER-
the original drug is not pharmacologically active but one
metabolite remains active
Inhibitors are - ANSWER-drugs that decrease medication
metabolism
What are inhibitors? - ANSWER-Inhibitors are compounds
(many of which are drugs) that inhibit the activity of the
enzyme. Enzyme inhibition result in less drug metabolism.
The drug serum level (and therapeutic effect) will increase.
This can result in drug toxicity.
Which neurotransmitter(s) may be responsible for a client's
symptoms of depression? Select all that apply. - ANSWER-
increased levels of acetylcholine
Correct answer.
decreased levels of norepinephrine
Correct answer.
decreased levels of histamine
Correct answer.
decreased levels of glutamate
Drug metabolism is influenced by which factors - ANSWER-age,
smoking, caffeine intake, or other medications
