MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
1. The process of formation and development of blood cells is
termed:a. Hematopoiesis b. Hematemesis
c. Hematocytometry d. Hematorrhea - ANSWER-a. Hematopoiesis
2. During the second trimester of fetal development, the primary site of
blood cell production is the:
a. Bone marrow b. Spleen
c. Lymph nodes d. Liver - ANSWER-d. Liver
3. Which one of the following organs is responsible for the maturation
of T lymphocytes and regulation of their expression of CD4 and CD8?
a. Spleen b. Liver c. Thymus d. Bone marrow - ANSWER-c. Thymus
4. The best source of active bone marrow from a 20-year-old would be:
a. Iliac crest b. Femur
c. Distal radius d. Tibia - ANSWER-a. Iliac crest
5. Physiologic programmed cell death is termed: a. Angiogenesis
b. Apoptosis c. Aneurysm d. Apohematics - ANSWER-b. Apoptosis
6. Which organ is the site of sequestration of platelets? a. Liver
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
b. Thymus c. Spleen d. Bone marrow - ANSWER-c. Spleen
7. Which one of the following morphologic changes occurs during
normal blood cell maturation:
a. Increase in cell diameter b. Development of cytoplasm basophilia c.
Condensation of nuclear chromatin d. Appearance of nucleoli -
ANSWER-c. Condensation of nuclear chromatin
8. Which one of the following cells is a product of the CLP? a.
Megakaryocyte
b. T lymphocyte c. Erythrocyte d. Granulocyte - ANSWER-b. T
lymphocyte
9. What growth factor is produced in the kidneys and is used to treat
anemia associated with kidney disease?
a. EPOb. TPO
c. G-CSF
d. KIT ligand - ANSWER-a. EPO
10. Which one of the following cytokines is required very early in the
differentiation of a hematopoietic stem cell?
a. IL-2
b. IL-8
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
c. EPO
d. FLT3 ligand - ANSWER-d. FLT3 ligand
11. When a patient has severe anemia and the bone marrow is unable
to effectively produce red blood cells to meet the increased demand,
one of the body's responses is: a. Extramedullary hematopoiesis in the
liver and spleen b. Decreased production of erythropoietin by the
kidney c. Increased apoptosis of erythrocyte progenitor cells d. Increase
the proportion of yellow marrow in the long bones - ANSWER-a.
Extramedullary hematopoiesis in the liver and spleen
12. Hematopoietic stem cells produce all lineages of blood cells in
sufficient quantities over the lifetime of an individual because they:
a. Are unipotent b. Have the ability of self-renewal by asymmetric
division c. Are present in large numbers in the bone marrow niches d.
Have a low mitotic potential in response to growth factors - ANSWER-b.
Have the ability of self-renewal by asymmetric division
1. Which of the following is an erythrocyte progenitor? a.
Pronormoblast
b. Reticulocyte c. CFU-E
d. Orthochromic normoblast - ANSWER-c. CFU-E
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
2. Which of the following is the most mature normoblast? a.
Orthochromic normoblast
b. Basophilic normoblast c. Pronormoblast
d. Polychromatic normoblast - ANSWER-a. Orthochromic normoblast
3. What erythroid precursor can be described as follows: the cell is of
medium size compared with other normoblasts, with an N:C ratio of
nearly 1:1. The nuclear chromatin is condensed and chunky throughout
the nucleus. No nucleoli are seen. The cytoplasm is a muddy, blue-pink
color. a. Reticulocyte
b. Pronormoblast
c. Orthochromic normoblast
d. Polychromatic normoblast - ANSWER-d. Polychromatic normoblast
4. Which of the following is not related to the effects of erythropoietin?
a. The number of divisions of a normoblast b. The formation of pores in
sinusoidal endothelial cells for marrow egress c. The time between
mitoses of normoblasts d. The production of antiapoptotic molecules
by erythroid progenitors - ANSWER-b. The formation of pores in
sinusoidal endothelial cells for
marrow egress
5. Hypoxia stimulates RBC production by: a. Inducing more pluripotent
stem cells into the erythroid lineage
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
1. The process of formation and development of blood cells is
termed:a. Hematopoiesis b. Hematemesis
c. Hematocytometry d. Hematorrhea - ANSWER-a. Hematopoiesis
2. During the second trimester of fetal development, the primary site of
blood cell production is the:
a. Bone marrow b. Spleen
c. Lymph nodes d. Liver - ANSWER-d. Liver
3. Which one of the following organs is responsible for the maturation
of T lymphocytes and regulation of their expression of CD4 and CD8?
a. Spleen b. Liver c. Thymus d. Bone marrow - ANSWER-c. Thymus
4. The best source of active bone marrow from a 20-year-old would be:
a. Iliac crest b. Femur
c. Distal radius d. Tibia - ANSWER-a. Iliac crest
5. Physiologic programmed cell death is termed: a. Angiogenesis
b. Apoptosis c. Aneurysm d. Apohematics - ANSWER-b. Apoptosis
6. Which organ is the site of sequestration of platelets? a. Liver
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
b. Thymus c. Spleen d. Bone marrow - ANSWER-c. Spleen
7. Which one of the following morphologic changes occurs during
normal blood cell maturation:
a. Increase in cell diameter b. Development of cytoplasm basophilia c.
Condensation of nuclear chromatin d. Appearance of nucleoli -
ANSWER-c. Condensation of nuclear chromatin
8. Which one of the following cells is a product of the CLP? a.
Megakaryocyte
b. T lymphocyte c. Erythrocyte d. Granulocyte - ANSWER-b. T
lymphocyte
9. What growth factor is produced in the kidneys and is used to treat
anemia associated with kidney disease?
a. EPOb. TPO
c. G-CSF
d. KIT ligand - ANSWER-a. EPO
10. Which one of the following cytokines is required very early in the
differentiation of a hematopoietic stem cell?
a. IL-2
b. IL-8
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
c. EPO
d. FLT3 ligand - ANSWER-d. FLT3 ligand
11. When a patient has severe anemia and the bone marrow is unable
to effectively produce red blood cells to meet the increased demand,
one of the body's responses is: a. Extramedullary hematopoiesis in the
liver and spleen b. Decreased production of erythropoietin by the
kidney c. Increased apoptosis of erythrocyte progenitor cells d. Increase
the proportion of yellow marrow in the long bones - ANSWER-a.
Extramedullary hematopoiesis in the liver and spleen
12. Hematopoietic stem cells produce all lineages of blood cells in
sufficient quantities over the lifetime of an individual because they:
a. Are unipotent b. Have the ability of self-renewal by asymmetric
division c. Are present in large numbers in the bone marrow niches d.
Have a low mitotic potential in response to growth factors - ANSWER-b.
Have the ability of self-renewal by asymmetric division
1. Which of the following is an erythrocyte progenitor? a.
Pronormoblast
b. Reticulocyte c. CFU-E
d. Orthochromic normoblast - ANSWER-c. CFU-E
, MLT ASCP EXAM LATEST 2023-2024 ACTUAL EXAM 200
QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) |ALREADY GRADED A
2. Which of the following is the most mature normoblast? a.
Orthochromic normoblast
b. Basophilic normoblast c. Pronormoblast
d. Polychromatic normoblast - ANSWER-a. Orthochromic normoblast
3. What erythroid precursor can be described as follows: the cell is of
medium size compared with other normoblasts, with an N:C ratio of
nearly 1:1. The nuclear chromatin is condensed and chunky throughout
the nucleus. No nucleoli are seen. The cytoplasm is a muddy, blue-pink
color. a. Reticulocyte
b. Pronormoblast
c. Orthochromic normoblast
d. Polychromatic normoblast - ANSWER-d. Polychromatic normoblast
4. Which of the following is not related to the effects of erythropoietin?
a. The number of divisions of a normoblast b. The formation of pores in
sinusoidal endothelial cells for marrow egress c. The time between
mitoses of normoblasts d. The production of antiapoptotic molecules
by erythroid progenitors - ANSWER-b. The formation of pores in
sinusoidal endothelial cells for
marrow egress
5. Hypoxia stimulates RBC production by: a. Inducing more pluripotent
stem cells into the erythroid lineage
