UTMB 5355 ADVANCED PATHOPHYSIOLOGY EXAM 3 QUESTIONS AND VERIFIED ANSWERS 2023/2024 LATEST GUIDE.

UTMB 5355 ADVANCED PATHOPHYSIOLOGY EXAM 3 QUESTIONS AND VERIFIED ANSWERS 2023/2024 LATEST GUIDE. 1. Biogenic Amine Theory linked to depression: Deficiency of neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin. Particularly, a decrease in receptor binding with serotonin. 2. Neurotransmitter Receptor Hypothesis linked to depression: A deficiency of monoamine neurotransmitters at neuronal synapses. 3. Antidepressants increase: Neuronal synaptic levels of monoamine neurotrans- mitters. 4. if you have more receptors than neurotransmitters: Neurotransmitters do not have time to recharge thus, they do not function properly. 5. Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation: HPA system dysregulation with excessive glucocorticoid secretion is found in a large percentage of people suffering from major depression. 6. Patho of Alzheimer's includes - plaque formation, presence of --, with de- creased levels of -: Amyloid B, neurofibrillary tangles, acetylcholine these disrupt impulse transmission 7. neurofibrillary tangles: are a deformation of the structure that carries nutrients to neurons of the brain. 8. Decreased levels of choline acetyl transferase and acetylcholine is associ- ated with: Memory loss 9. Most common cause of dementia: Alzheimer's disease fatal 5-10 years 10. Characteristics of Alzheimer's: Loss of memory, language , inability to learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects social life 11. Parkinson's Disease is: Chronic motor progressive neuro-degenerative known as a shaking palsy 12. Parkinson's disease is associated with: basal ganglia dysfunction and atro- phy of neurons in the substantia nigra that produce dopamine;