Concise summary of molecular infection biology

,
, L
?
Which pathogen strain to use Variation cause/driving forces
:




Bacteria

strain .
-> HGT
to badquality


sequenced
Viruses -> Mutations (Due
DNA/RNA polymeraseR
transcriptase)
Use the
reverse
- > Within
retroviruses'




- Genetics
-
Yes Proteonics ->


& Easier to data
exchange f it is
-rucoid
attenuated - You can test this if ↑
Can be
↑. produces alginate
Hot
still
Geruginosa
-



-> Genome plasti cy
·




Example
:
factor
->
virulence on
Mycolactone
↳ M Ukerans
plasmid transfered .




toxin)
↳
Big 'player E-> HET ->
3
bacteriophages (cholera
is lands
important for pathogenicety
virulence
-

, less
variability
strain to use ?
->
Viruses
Which pathogen
M

+ Use
DNA viruses of the host =D Less errors
·
machinary
with
experimenting
new
Bigger->
More room
*
genome
->
for
Can also be host
genes,
like :


genes * EBV - VIC-10
homolong More
variabilit
RNA-polymerase &
* Poxvirus -> TNFR
Y
&
Lots of errors
· RNA viruses -> Use their own
machinary =


↳ Also with retroviruses -> Reverse
transcriptase is bad
* Smaller -> Less room for other
genes
genome