INTEGRATION OF METABOLISM

INTEGRATION OF METABOLISM

, INTEGRATION OF METABOLISM
• Metabolism is a continuous process with thousands of reactions occurrin
inside the living cell
• It keeps cells alive giving them energy and building blocks for growth an
propagation
• Though metabolism of carbohydrates, lipids and proteins are considered
separately for convenience, they takes place simultaneously
• They are interrelated to one another
• The co-ordination between the metabolic pathways of three major metab
is called Integration of metabolism
• All the major metabolic pathways do not operate in every tissue at any g
time
• However cells and organs cooperate and together they control everyday
challenges like well fed, fasting and muscular activity state

, SIGNIFICANCE OF INTEGRATION OF
METABOLISM
• Significance of Integration of metabolism is that energy supply is maintain
the time from fully fed state to totally starved state

• It also ensures a supply of suitable fuel for all the tissues

• In well fed state:
- There is positive caloric balance and
- Significant amount of food energy intake is stored as either glycogen or
• In starvation:
- There is negative caloric balance.
- Glucose is spared for brain and RBCs
- Fatty acids are oxidised to provide energy for other tissues