Ubiquitination is a means of targeting a protein for which of the following cellular
processes?
Proteasomal degradation
The reaction of ammonia with a-ketoglutarate is catalyzed by_______ and
requires ________ as a reactant?
Glutamate dehydrogenase; NADH or NADPH
Most enzymes involved in a protein digestion require cleavage for activation.
These proteins are secreted as inactive protein forms called:
Zymogens
The urea cycle takes place in which of the following sub cellular locations?
the cytosol and mitochondria
Which of the following amino acids is considered non essential because its
generated by the urea cycle?
arginine
Which of the following enzymes is regulated by N-acteyl glutamate (NAGs)?
CPS I
Which of the following enzymes is correctly paired with its activator?
N-acetylglutamate synthase; arginine
Which of the following enzymes will be active in both the fed and fasted state?
Glutaminase
Which of the following compounds stimulates the synthesis of N-
acetylglutamate?
arginine
Which of the following statements is consistent with nitrogen transport in the
fasted state
Glutaminase will be active
Which of the following is the primary role of glutaminase in the liver?
to free an amine group from glutamine
in the case of urea cycle deficiency, which of the following amino acids may
become essential?
arginine
When is the process of autophage most likely occurring in the cell?
When there is low energy in the cell; ratio of AMP/ATP >1
Unlike many of the other metabolic pathways, the urea cycle can be active under
which of the following conditions?
Both the fed and fasted state
Pepsinogen is activated by which of the following mechanisms or enzymes?
A change in pH catalyzes the activation of pepsinogen to pepsin
The process of autophagy is defined as which of the following processes?
Recycling of proteins under conditions of cellular need or starvation
Which of the following enzymes is the regulatory step in the urea cycle?
Carbamoyl phosphate synthetase (CPSI)
The pancreatic zymogen trypsinogen is activated by which of the following
enzymes or compounds?