UNE biochem Unit 1 Test Questions And Answers.
Allopurinol is an inhibitor of Xanthine Oxidase. Addition of this compound will
result in a decrease in what compound?
Uric Acid
DNA replication occurs during which phase of the cell cycle?
S phase
The affinity for DNA and histones within a chromosome can be increased by
which of the following histone modifications?
Deaceytlation
DNA replication on both the leading and the lagging strand proceeds in the 5' to
3' direction. The remaining over hand on the lagging strand requires priming from
which of the following enzymes in order for the gap to be filled?
Telomerase
Which of the following is the regulatory enzyme in pyrimidine synthesis?
Carbamoyl phosphate synthetase II
You are counseling a family with regards to myotonic dystrophy which is an
autosomal dominant disorder. One of the individuals is affected by this disorder
(genotype Rr) while the other is not. What is the likelihood that their child will not
be impacted by myotonic dystrophy?
50%
Cobalamin (B12) supplementation would be most appropriate to enhance the
activity of which of the following enzymes?
Methionine Synthase
In the case of a deficiency in phenylalanine hydroxylase which of the following
amino acids will become essential?
Tyrosine
Phenylketonuria (PKU) is an autosomal recessive disorder that can be caused by
a defect in phenylalanine hydroxylase. PKU can also present due to a deficiency
in which of the following vitamins or cofactors?
Tetrahydrobiopterin (B4)
A 2-year-old boy is recently diagnosed with red-green blindness which is an X-
linked recessive disorder. Which of the following represents the correct
genotypes of this individual's parents with respect to red-green color blindness?
(X-wild type, X'- recessive allele; R wild type autosomal allele; r recessive
autosomal allele and Y chromosome)
Mom X'X and Dad XY
Which of the following amino acids could be readily modified by
phosphorylation?
Tyrosine
In the image above the blue line indicates enzyme kinetics with no inhibitor
present. Based on this information which of the following is true?
The green line shows enzyme kinetics with the addition of a noncompetitive inhibitor
What is the [H+] concentration in a 0.001M = 10^-3 M solution of NaOH. (10^-14 =
[H+][OH-])
10^-11 M
Allopurinol is an inhibitor of Xanthine Oxidase. Addition of this compound will
result in a decrease in what compound?
Uric Acid
DNA replication occurs during which phase of the cell cycle?
S phase
The affinity for DNA and histones within a chromosome can be increased by
which of the following histone modifications?
Deaceytlation
DNA replication on both the leading and the lagging strand proceeds in the 5' to
3' direction. The remaining over hand on the lagging strand requires priming from
which of the following enzymes in order for the gap to be filled?
Telomerase
Which of the following is the regulatory enzyme in pyrimidine synthesis?
Carbamoyl phosphate synthetase II
You are counseling a family with regards to myotonic dystrophy which is an
autosomal dominant disorder. One of the individuals is affected by this disorder
(genotype Rr) while the other is not. What is the likelihood that their child will not
be impacted by myotonic dystrophy?
50%
Cobalamin (B12) supplementation would be most appropriate to enhance the
activity of which of the following enzymes?
Methionine Synthase
In the case of a deficiency in phenylalanine hydroxylase which of the following
amino acids will become essential?
Tyrosine
Phenylketonuria (PKU) is an autosomal recessive disorder that can be caused by
a defect in phenylalanine hydroxylase. PKU can also present due to a deficiency
in which of the following vitamins or cofactors?
Tetrahydrobiopterin (B4)
A 2-year-old boy is recently diagnosed with red-green blindness which is an X-
linked recessive disorder. Which of the following represents the correct
genotypes of this individual's parents with respect to red-green color blindness?
(X-wild type, X'- recessive allele; R wild type autosomal allele; r recessive
autosomal allele and Y chromosome)
Mom X'X and Dad XY
Which of the following amino acids could be readily modified by
phosphorylation?
Tyrosine
In the image above the blue line indicates enzyme kinetics with no inhibitor
present. Based on this information which of the following is true?
The green line shows enzyme kinetics with the addition of a noncompetitive inhibitor
What is the [H+] concentration in a 0.001M = 10^-3 M solution of NaOH. (10^-14 =
[H+][OH-])
10^-11 M
