Chapter 11, Antiviral Drugs TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION By Susan M Ford

TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION By Susan M Ford 1. A nurse is obtaining the medication history of a client who is to start acyclovir. The nurse discovers this client is currently taking theophylline. The nurse should question the use of acyclovir due to which contraindication? A) Increases the risk for acyclovir toxicity B) Increases the risk of seizures in clients with respiratory problems C) Increases serum level of theophylline in clients taking theophylline D) Increased serum levels of antiviral valacyclovir Answer: C Rationale: When clients receiving theophylline treatment are administered acyclovir, there is an increase in the serum level of theophylline, thus placing the client at risk for theophylline toxicity. The serum levels of acyclovir do not increase. Increased levels of valacyclovir occur if the client is taking valacyclovir, not theophylline. Taking acyclovir with theophylline does not increase the risk of seizures. Question Format: Multiple Choice Chapter: 11 Learning Objective: 5 Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 129, Unlabeled Use of Antiviral Drugs 2. The nurse monitoring a client receiving saquinavir assesses the client for responses. Which reaction requires priority response? A) Increase in client's weight B) Evidence of liver dysfunction C) Photosensitivity D) Allergic skin reaction Answer: A Rationale: Clients taking saquinavir experience redistribution of body fat, with the movement to the center of the body. The nurse should spend time with these clients, encouraging them to verbalize their feelings regarding this change in appearance. Taking saquinavir does not cause liver dysfunction, photosensitivity, or any allergic skin reactions. Question Format: Multiple Choice Chapter: 11 Learning Objective: 5 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process)