NSG 6005 WEEK 2 QUIZ SOUTH UNIVERSITY
GRADED A+ 100% CORRECT NOVEMBER
Quarter (all you need)
Chapter 2: Review of Basic Principles of Pharmacology
1. A client’s nutritional intake and lab work reflects hypoalbuminemia. This is critical
to prescribing because:
A. Distribution of drugs to target tissue may be affected
2. Drugs that have a significant first-pass effect:
C. Are rapidly metabolized by the liver and may have little if any desired action
3. The route of excretion of a volatile drug will likely be:
B. The lungs
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir
ofthe drug. Storage reservoirs:
C. Increase the length of time a drug is available and active
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
B. Biological half-life
6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days
ofthe prescription. This is considered a loading dose. A loading dose:
A. Rapidly achieves drug levels in the therapeutic range
7. The point in time on the drug concentration curve that indicates the first sign
of atherapeutic effect is the:
C. Onset of action
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
D. To determine if a drug is in the therapeutic range
, 9. A laboratory result indicates the peak level for a drug is above the minimum
toxicconcentration. This means that the:
B. Concentration will produce an adverse response
10. Drugs that are receptor agonists may demonstrate what property?
C. Desensitization or down-regulation with continuous use
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
B. An exaggerated response if abruptly discontinued
12. Factors that affect gastric drug absorption include:
C. Lipid solubility of the drug
13. Drugs administered via intravenous (IV) route:
B. Begin distribution into the body immediately
14. When a medication is added to a regimen for a synergistic effect, the combined effect
ofthe drugs is:
B. Greater than the sum of the effects of each drug individually
15. Which of the following statements about bioavailability is true?
• Bioavailability issues are especially important for drugs with narrow therapeutic ranges
orsustained release mechanisms.
16. Which of the following statements about the major distribution barriers (blood-brain
orfetal placental) is true?
• The blood-brain barrier slows the entry of many drugs into and from brain cells.
17. Drugs are metabolized mainly by the liver via Phase I or Phase II reactions.
Thepurpose of both of these types of reactions is to:
• Change drug molecules to a form that an excretory organ can excrete
18. Once they have been metabolized by the liver, the metabolites may be:
• More active than the parent drug
GRADED A+ 100% CORRECT NOVEMBER
Quarter (all you need)
Chapter 2: Review of Basic Principles of Pharmacology
1. A client’s nutritional intake and lab work reflects hypoalbuminemia. This is critical
to prescribing because:
A. Distribution of drugs to target tissue may be affected
2. Drugs that have a significant first-pass effect:
C. Are rapidly metabolized by the liver and may have little if any desired action
3. The route of excretion of a volatile drug will likely be:
B. The lungs
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir
ofthe drug. Storage reservoirs:
C. Increase the length of time a drug is available and active
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
B. Biological half-life
6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days
ofthe prescription. This is considered a loading dose. A loading dose:
A. Rapidly achieves drug levels in the therapeutic range
7. The point in time on the drug concentration curve that indicates the first sign
of atherapeutic effect is the:
C. Onset of action
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
D. To determine if a drug is in the therapeutic range
, 9. A laboratory result indicates the peak level for a drug is above the minimum
toxicconcentration. This means that the:
B. Concentration will produce an adverse response
10. Drugs that are receptor agonists may demonstrate what property?
C. Desensitization or down-regulation with continuous use
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
B. An exaggerated response if abruptly discontinued
12. Factors that affect gastric drug absorption include:
C. Lipid solubility of the drug
13. Drugs administered via intravenous (IV) route:
B. Begin distribution into the body immediately
14. When a medication is added to a regimen for a synergistic effect, the combined effect
ofthe drugs is:
B. Greater than the sum of the effects of each drug individually
15. Which of the following statements about bioavailability is true?
• Bioavailability issues are especially important for drugs with narrow therapeutic ranges
orsustained release mechanisms.
16. Which of the following statements about the major distribution barriers (blood-brain
orfetal placental) is true?
• The blood-brain barrier slows the entry of many drugs into and from brain cells.
17. Drugs are metabolized mainly by the liver via Phase I or Phase II reactions.
Thepurpose of both of these types of reactions is to:
• Change drug molecules to a form that an excretory organ can excrete
18. Once they have been metabolized by the liver, the metabolites may be:
• More active than the parent drug
