TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY
12TH EDITION By Susan M Ford
Chapter 29, Skeletal Muscle, Bone, and Joint Disorder Drugs
1. A nurse is teaching a client with gout the importance of getting adequate fluids.
The nurse determines the session is successful when the client correctly plans to
drink at least how much fluid each day?
A) 1000 mL
B) 1500 mL
C) 2000 mL
D) 3000 mL
Answer: D
Rationale: A client with gout is encouraged to drink at least 3000 mL of fluid per
day to promote uric acid excretion.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Physiological Adaptation
Integrated Process: Teaching/Learning
Reference: p. 358, Readiness for Enhanced Fluid Balance
2. A client is receiving alendronate for osteoporosis. The client has informed the
nurse that they have also been taking aspirin. Which interaction should the nurse
monitor for in this client?
A) Increased risk of GI bleeding
B) Decreased effects of bisphosphonate
C) Increased level of sedation
D) Increased risk of rash
Answer: A
Rationale: Interaction of aspirin with a bisphosphonate drug causes increased risk
of GI bleeding, which requires monitoring. Interaction of a uric acid inhibitor with
barbiturates and benzodiazepines causes an increased level of sedation.
Interaction of a uric acid inhibitor with ampicillin causes increased risk of rash.
Interaction of calcium supplements or antacids with bisphosphonates decreases
the effects of bisphosphonates.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 3
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 355, Contraindications and Precautions
, 3. A nurse is caring for a client who is receiving cyclobenzaprine. The nurse would
expect to assess which finding as indicating the therapeutic effect of the drug?
A) Reduction of muscle spasm
B) Prevention of seizure
C) Relief from anxiety
D) Relief from nervous disorder
Answer: A
Rationale: Cyclobenzaprine, a skeletal muscle relaxant, affects muscle tone,
thereby causing reduction of muscle spasm. Antiepileptics are used to prevent
seizures. Benzodiazepines are used for anxiety. There are a variety of nervous
disorders, and they can be treated with amphetamines, analeptics, anorexiants,
cholinesterase inhibitors, adrenergics, adrenergic blocking agents, cholinergics,
cholinergic blocking agents, anti-Parkinson, and antiepileptics.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 2
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 352, Skeletal Muscle Relaxants
4. The nurse is preparing to administer colchicine to a client who is in the initial
phase of gout. Which disorder will the nurse be prepared to monitor the client for?
A) Stomatitis
B) Stevens–Johnson syndrome
C) Bone marrow depression
D) Exfoliative dermatitis
Answer: C
Rationale: The nurse needs to closely monitor the client for bone marrow
depression, an adverse reaction of colchicine. Stomatitis, Stevens–Johnson
syndrome, and exfoliative dermatitis are not adverse reactions of colchicine.
Stomatitis is an adverse reaction of immunosuppressive drugs. Stevens–Johnson
syndrome and exfoliative dermatitis are adverse reactions of allopurinol.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 3
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 356, Gastrointestinal System Reactions
5. The nurse is teaching a client about the medication they are receiving as
treatment for gout. The nurse determines the session is successful when the
client correctly chooses which instruction as most important?
A) Taking drug on an empty stomach
12TH EDITION By Susan M Ford
Chapter 29, Skeletal Muscle, Bone, and Joint Disorder Drugs
1. A nurse is teaching a client with gout the importance of getting adequate fluids.
The nurse determines the session is successful when the client correctly plans to
drink at least how much fluid each day?
A) 1000 mL
B) 1500 mL
C) 2000 mL
D) 3000 mL
Answer: D
Rationale: A client with gout is encouraged to drink at least 3000 mL of fluid per
day to promote uric acid excretion.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Physiological Adaptation
Integrated Process: Teaching/Learning
Reference: p. 358, Readiness for Enhanced Fluid Balance
2. A client is receiving alendronate for osteoporosis. The client has informed the
nurse that they have also been taking aspirin. Which interaction should the nurse
monitor for in this client?
A) Increased risk of GI bleeding
B) Decreased effects of bisphosphonate
C) Increased level of sedation
D) Increased risk of rash
Answer: A
Rationale: Interaction of aspirin with a bisphosphonate drug causes increased risk
of GI bleeding, which requires monitoring. Interaction of a uric acid inhibitor with
barbiturates and benzodiazepines causes an increased level of sedation.
Interaction of a uric acid inhibitor with ampicillin causes increased risk of rash.
Interaction of calcium supplements or antacids with bisphosphonates decreases
the effects of bisphosphonates.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 3
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 355, Contraindications and Precautions
, 3. A nurse is caring for a client who is receiving cyclobenzaprine. The nurse would
expect to assess which finding as indicating the therapeutic effect of the drug?
A) Reduction of muscle spasm
B) Prevention of seizure
C) Relief from anxiety
D) Relief from nervous disorder
Answer: A
Rationale: Cyclobenzaprine, a skeletal muscle relaxant, affects muscle tone,
thereby causing reduction of muscle spasm. Antiepileptics are used to prevent
seizures. Benzodiazepines are used for anxiety. There are a variety of nervous
disorders, and they can be treated with amphetamines, analeptics, anorexiants,
cholinesterase inhibitors, adrenergics, adrenergic blocking agents, cholinergics,
cholinergic blocking agents, anti-Parkinson, and antiepileptics.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 2
Cognitive Level: Understand
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 352, Skeletal Muscle Relaxants
4. The nurse is preparing to administer colchicine to a client who is in the initial
phase of gout. Which disorder will the nurse be prepared to monitor the client for?
A) Stomatitis
B) Stevens–Johnson syndrome
C) Bone marrow depression
D) Exfoliative dermatitis
Answer: C
Rationale: The nurse needs to closely monitor the client for bone marrow
depression, an adverse reaction of colchicine. Stomatitis, Stevens–Johnson
syndrome, and exfoliative dermatitis are not adverse reactions of colchicine.
Stomatitis is an adverse reaction of immunosuppressive drugs. Stevens–Johnson
syndrome and exfoliative dermatitis are adverse reactions of allopurinol.
Question format: Multiple Choice
Chapter: 29
Learning Objective: 3
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 356, Gastrointestinal System Reactions
5. The nurse is teaching a client about the medication they are receiving as
treatment for gout. The nurse determines the session is successful when the
client correctly chooses which instruction as most important?
A) Taking drug on an empty stomach
