TEST BANK INTRODUCTORY CLINICAL
PHARMACOLOGY 12TH EDITION By Susan M Ford
Chapter 22, Antipsychotic Drugs
1. The nurse is caring for a client diagnosed with HIV. The nurse should question a
new order for clozapine due to which currently prescribed drug?
A) Immunologics
B) Anticholinergics
C) Opioids
D) Anticoagulants
Answer: A
Rationale: Immunological agents are used to treat HIV. It is contraindicated to
give a client with bone marrow suppression clozapine. The concomitant use of
clozapine and immunological drugs can increase the severity of bone marrow
suppression. The use of anticholinergics in combination with antipsychotics can
increase the risk of tardive dyskinesia and psychotic symptoms. Opioids and
anticoagulants are not associated with interactions involving antipsychotic drugs.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 270, Interactions
2. The nurse is conducting an ongoing assessment of a client who is prescribed
loxapine. Which finding is most likely attributable to this medication?
A) Hypertension
B) Skin dryness
C) Dry mouth
D) Bradycardia
Answer: C
Rationale: Antipsychotics such as loxapine may cause adverse effects of dry
mouth, drowsiness, akathisia, EPS, headache, and orthostatic hypotension.
Antipsychotics are contraindicated in clients with severe hypertension.
Bradycardia can be a sign of hypertensive crisis, which is an adverse effect of
MAOIs. Skin dryness is a recognized adverse effect to clofazimine, a drug used to
treat M. leprae.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 2
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
, Reference: p. 275, Summary Drug Table
3. A client who has been receiving treatment for psychosis presents to the clinic for
follow up. On assessment, the nurse discovers the client is currently displaying
rhythmic, involuntary facial movements to include chewing-like movements and
tongue protrusion. The nurse interprets these findings as an indication of which
disorder?
A) Stevens–Johnson syndrome
B) Neuroleptic malignant syndrome
C) Tardive dyskinesia
D) Extrapyramidal syndrome
Answer: C
Rationale: Tardive dyskinesia is irreversible and characterized by rhythmic,
involuntary movements of the tongue, face, mouth, or jaw and sometimes the
extremities. The tongue may protrude, and there may be chewing movements,
puckering of the mouth, and facial grimacing. Extrapyramidal syndrome (EPS),
neuroleptic malignant syndrome (NMS), and Stevens–Johnson syndrome (SJS)
do not cause rhythmic, involuntary facial movements. SJS is a hypersensitivity
reaction to various antibiotics and presents with fever, cough, muscle aches and
pains, headaches, and lesions on the skin, mucous membranes, and eyes. NMS is
a combination of extrapyramidal syndrome, hyperthermia, and autonomic
disturbance. It is similar to TD with muscle rigidity, altered mental status, and
autonomic system problems; however, it is a reversible reaction to TCAs. EPS is
related to conventional antipsychotics with Parkinson-like symptoms, akathisia,
and dystonia. The effects diminish with a reduction in dosage.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 1
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 269, Tardive Dyskinesia
4. A nurse is preparing a teaching plan for a client with schizophrenia who is
prescribed olanzapine in a disintegrating tablet form. Which instruction should the
nurse include in the teaching?
A) Remove the tablet with dry hands.
B) Take the tablet with a full glass of water.
C) Add extra salt to food.
D) Avoid tea or coffee.
Answer: A
PHARMACOLOGY 12TH EDITION By Susan M Ford
Chapter 22, Antipsychotic Drugs
1. The nurse is caring for a client diagnosed with HIV. The nurse should question a
new order for clozapine due to which currently prescribed drug?
A) Immunologics
B) Anticholinergics
C) Opioids
D) Anticoagulants
Answer: A
Rationale: Immunological agents are used to treat HIV. It is contraindicated to
give a client with bone marrow suppression clozapine. The concomitant use of
clozapine and immunological drugs can increase the severity of bone marrow
suppression. The use of anticholinergics in combination with antipsychotics can
increase the risk of tardive dyskinesia and psychotic symptoms. Opioids and
anticoagulants are not associated with interactions involving antipsychotic drugs.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 270, Interactions
2. The nurse is conducting an ongoing assessment of a client who is prescribed
loxapine. Which finding is most likely attributable to this medication?
A) Hypertension
B) Skin dryness
C) Dry mouth
D) Bradycardia
Answer: C
Rationale: Antipsychotics such as loxapine may cause adverse effects of dry
mouth, drowsiness, akathisia, EPS, headache, and orthostatic hypotension.
Antipsychotics are contraindicated in clients with severe hypertension.
Bradycardia can be a sign of hypertensive crisis, which is an adverse effect of
MAOIs. Skin dryness is a recognized adverse effect to clofazimine, a drug used to
treat M. leprae.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 2
Cognitive Level: Remember
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
, Reference: p. 275, Summary Drug Table
3. A client who has been receiving treatment for psychosis presents to the clinic for
follow up. On assessment, the nurse discovers the client is currently displaying
rhythmic, involuntary facial movements to include chewing-like movements and
tongue protrusion. The nurse interprets these findings as an indication of which
disorder?
A) Stevens–Johnson syndrome
B) Neuroleptic malignant syndrome
C) Tardive dyskinesia
D) Extrapyramidal syndrome
Answer: C
Rationale: Tardive dyskinesia is irreversible and characterized by rhythmic,
involuntary movements of the tongue, face, mouth, or jaw and sometimes the
extremities. The tongue may protrude, and there may be chewing movements,
puckering of the mouth, and facial grimacing. Extrapyramidal syndrome (EPS),
neuroleptic malignant syndrome (NMS), and Stevens–Johnson syndrome (SJS)
do not cause rhythmic, involuntary facial movements. SJS is a hypersensitivity
reaction to various antibiotics and presents with fever, cough, muscle aches and
pains, headaches, and lesions on the skin, mucous membranes, and eyes. NMS is
a combination of extrapyramidal syndrome, hyperthermia, and autonomic
disturbance. It is similar to TD with muscle rigidity, altered mental status, and
autonomic system problems; however, it is a reversible reaction to TCAs. EPS is
related to conventional antipsychotics with Parkinson-like symptoms, akathisia,
and dystonia. The effects diminish with a reduction in dosage.
Question Format: Multiple Choice
Chapter: 22
Learning Objective: 1
Cognitive Level: Analyze
Client Needs: Physiological Integrity: Pharmacological Therapies
Integrated Process: Clinical Problem-solving Process (Nursing Process)
Reference: p. 269, Tardive Dyskinesia
4. A nurse is preparing a teaching plan for a client with schizophrenia who is
prescribed olanzapine in a disintegrating tablet form. Which instruction should the
nurse include in the teaching?
A) Remove the tablet with dry hands.
B) Take the tablet with a full glass of water.
C) Add extra salt to food.
D) Avoid tea or coffee.
Answer: A
