Chapter 39, Lower Gastrointestinal System Drugs TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION By Susan M Ford

TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION By Susan M Ford 1. A nurse is preparing to administer sulfasalazine to a client with inflammatory bowel disease. The nurse should question this order if the client's record indicates a hypersensitivity to which drug? A) Enalapril B) Doxycycline C) Azithromycin D) Sulfamethoxazole/trimethoprim Answer: D Rationale: Sulfasalazine is an aminosalicylate. The use of aminosalicylates is contraindicated in clients with hypersensitivity to sulfonamides and sulfites, which includes sulfamethoxazole/trimethoprim. There are no recognized interactions between sulfonamides and sulfites and enalapril, doxycycline, or azithromycin. Question Format: Multiple Choice Chapter: 39 Learning Objective: 3 Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 512, Antidiarrheals 2. After teaching a group of nursing students about laxatives, the instructor determines that the teaching was successful when the students correctly choose which drug as producing the laxative effect by promoting water retention and softening the stool? A) Docusate B) Methylcellulose C) Bisacodyl D) Lactulose Answer: A Rationale: A stool softener, like docusate, produces its laxative effect by promoting water retention in the fecal mass and softening the stool. Methylcellulose is a bulk-producing laxative. Bisacodyl is a stimulant laxative. Lactulose is a hyperosmolar laxative. Question Format: Multiple Choice Chapter: 39 Learning Objective: 2 Cognitive Level: Remember Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Teaching/Learning Reference: p. 519, Summary Drug Table