, What are General Anesthetics?
A drug that brings about a reversible
loss of consciousness.
These drugs are generally
administered by an anesthesiologist in
order to induce or maintain general
anesthesia to facilitate surgery.
,History of Anesthesia
General anesthesia was absent
until the mid-1800’s
William Morton administered
ether to a patient having a neck
tumor 1846.
•Chloroform used as anesthetic in
1853 by Dr. John Snow
• Endotracheal tube discovered in
1878
•Thiopental first used in 1934
, Principles of General Anesthesia
General anesthesia is essential to surgical
practice, because it renders patients:
• Analgesic
• Amnesic
• Unconscious
• Provides muscle relaxation
• Suppression of undesirable reflexes.
No single drug is capable of achieving these
effects both rapidly and safely.