ofdestruction
if egg rate
Hematological disorder due to as
Corpuscular membrane as defect enzyme defect
Extra corpuscular Immue
Hypersplenism firms Easie
Infection ex malaria
Trauma ex Artificialvalve March hemoglobinuria DIC
Toxic ex leat coppersnake venom
1 Hemolytic Jaundice Pecten urine n son works
11 IntravascularHemolysis Tubulardamage Hemoglobinuria Dark urine
111ExtravascularHemolysis Hepatosplenomegaly
IV Hemolyticcrisis Fever RigorDeepening of Jaundice
Bone Pain Hyperactivation of Bm
kidney Pain Tubular damage
AbdominalPain ischemia
Investigations
1 CBC Normocktic Normochromic w Reticulocytosis
Reticulocytic comme except in Aplastic crisis
Hypercellular norm blasts megaloblastic in 2ryfolicacid deficienc
BM
111InvForHemolyticJaundice serum umconjugated bilirubin
sterocobilinogen Darkstool
Ir Inv forIntravascularhemolysis Diminishedhemopexin Haploglobin
v Coomb's test Detect AB against RBCS tue in immunehemolytic Anemia
99magainst 195 Direct AB on surfaceofRBCs indirect AB in Plasma
1 RBCS life span 215days com emolytic state Bm activity
11 Hemolytic Jaundice unconjugated bilirubin
in Intravascular hemolysis Hemoglobinuria Tubulardamage Darkurine
Iv Extravascularhemolysis in RES Hepatosplenomegaly
freshblood transfusion a spten Tf in treat the cause
E
megaloblasticcrisis due to development of folic acid deficiency
Aplastic crisis viral inf inhibit BM Anemia w o Deepening of Jaundice
if egg rate
Hematological disorder due to as
Corpuscular membrane as defect enzyme defect
Extra corpuscular Immue
Hypersplenism firms Easie
Infection ex malaria
Trauma ex Artificialvalve March hemoglobinuria DIC
Toxic ex leat coppersnake venom
1 Hemolytic Jaundice Pecten urine n son works
11 IntravascularHemolysis Tubulardamage Hemoglobinuria Dark urine
111ExtravascularHemolysis Hepatosplenomegaly
IV Hemolyticcrisis Fever RigorDeepening of Jaundice
Bone Pain Hyperactivation of Bm
kidney Pain Tubular damage
AbdominalPain ischemia
Investigations
1 CBC Normocktic Normochromic w Reticulocytosis
Reticulocytic comme except in Aplastic crisis
Hypercellular norm blasts megaloblastic in 2ryfolicacid deficienc
BM
111InvForHemolyticJaundice serum umconjugated bilirubin
sterocobilinogen Darkstool
Ir Inv forIntravascularhemolysis Diminishedhemopexin Haploglobin
v Coomb's test Detect AB against RBCS tue in immunehemolytic Anemia
99magainst 195 Direct AB on surfaceofRBCs indirect AB in Plasma
1 RBCS life span 215days com emolytic state Bm activity
11 Hemolytic Jaundice unconjugated bilirubin
in Intravascular hemolysis Hemoglobinuria Tubulardamage Darkurine
Iv Extravascularhemolysis in RES Hepatosplenomegaly
freshblood transfusion a spten Tf in treat the cause
E
megaloblasticcrisis due to development of folic acid deficiency
Aplastic crisis viral inf inhibit BM Anemia w o Deepening of Jaundice
