USMLE Step 1 Microbiology B
Treatment for H. pylori - answertriple therapy: proton pump inhibitor, clarithromycin, &
metronidazole
Urease positive bugs - answerCHuck norris hates PUNKSS
Cryptococcus, H. pylori, Proteus, Ureaplasma, Norcardia, Klebsiella, S. saprophyticus
H. pylori increases risk for what diseases? - answerpeptic ulcer, gastric adenocarinoma,
lymphoma
which enteric bug is thermophilic? - answercampylobacter jejuni
reactive arthritis bugs - answerchlamydia, salmonella, shigella, yersinia, campylobacter
bugs that cause urolithiasis - answeropportunistic enterics with urease: Klebsiella,
Proteus
bugs that cause spontaneous abortion - answercampylobacter fetus fetus
name the lactose fermenters - answermaConKEES: Citrobacter, Klebsiella, E. coli,
Enterobacter, Serratia (remember Proteus is normal flora but not lactose fermenter)
rice water stools - answervibrio cholerae
rose spots on abdomen, fever, headache, diarrhea - answersalmonella typhi
what type of immune cell attacks salmonella - answermoncytic (macrophages &
lymphocytes)
what type of immune cell attacks shigella - answerPMNs
MOA of shiga toxin - answerA/B toxin that inhibits host 60S protein synthesis
MOA of shiga-like toxin - answerin EHEC, A/B toxin that inhibits host 28S protein
synthesis
, produces H2S+: shigella vs salmonella - answersalmonella
safety pin staining - answeryersinia enterocolitica
name the spirochetes - answerBLT: Borrelia (big), Leptospira, Treponema
what bug causes Lyme disease - answerBorrelia burgdorferi
erythema migrans - answerfirst stage of Lyme dz, "bull's eye" rash with clear center
what is second stage of Lyme dz? - answerneurologic- limb numbness, Bell's palsy,
meningitis, encephalitis, cardiac (AV block, myocarditis)
what is third stage of Lyme dz? - answerchronic neurologic impairments and
polyarthritis
only spirochete stains with Giema or Wright stain? - answerBorrelia
microaerobic bugs - answercampylobacter, H. pylori, borrelia burgdorferi
vector of Lyme dz - answerhard bodied deer ticks (Ixodes)
natural reservoir: mouse
(also vector for Babesia)
tx for Lyme dz - answeramoxicillin 30-60 days
if neurologic or cardiac too, use IV ceftriaxone
cause of epidemic relapsing fever & vector - answerBorrelia recurrentis, vector: human
body louse
cause of endemic relapsing fever & vector - answerBorrelia parkeri, hermsii, turicatae
vector: soft-bodied tick
what is the Jarish-Herxheimer rxn? - answerflu-like symptoms immediately after
antibiotics are started due to killed bacteria releasing pyrogens
obligate aerobes - answerNasty Pests Must Breathe
Nocardia, Pseudomonas, Mycobacterium tuberculosis, Bacillus
what drug can suppress the immune system and allow a reaction of TB? - answerTNF-
alpha inhibitors
what part of lung do reactivations of TB usually affect? why? - answerapices; highest
PO2
hot tub folliculitis - answerPseudomonas aeruginosa
Treatment for H. pylori - answertriple therapy: proton pump inhibitor, clarithromycin, &
metronidazole
Urease positive bugs - answerCHuck norris hates PUNKSS
Cryptococcus, H. pylori, Proteus, Ureaplasma, Norcardia, Klebsiella, S. saprophyticus
H. pylori increases risk for what diseases? - answerpeptic ulcer, gastric adenocarinoma,
lymphoma
which enteric bug is thermophilic? - answercampylobacter jejuni
reactive arthritis bugs - answerchlamydia, salmonella, shigella, yersinia, campylobacter
bugs that cause urolithiasis - answeropportunistic enterics with urease: Klebsiella,
Proteus
bugs that cause spontaneous abortion - answercampylobacter fetus fetus
name the lactose fermenters - answermaConKEES: Citrobacter, Klebsiella, E. coli,
Enterobacter, Serratia (remember Proteus is normal flora but not lactose fermenter)
rice water stools - answervibrio cholerae
rose spots on abdomen, fever, headache, diarrhea - answersalmonella typhi
what type of immune cell attacks salmonella - answermoncytic (macrophages &
lymphocytes)
what type of immune cell attacks shigella - answerPMNs
MOA of shiga toxin - answerA/B toxin that inhibits host 60S protein synthesis
MOA of shiga-like toxin - answerin EHEC, A/B toxin that inhibits host 28S protein
synthesis
, produces H2S+: shigella vs salmonella - answersalmonella
safety pin staining - answeryersinia enterocolitica
name the spirochetes - answerBLT: Borrelia (big), Leptospira, Treponema
what bug causes Lyme disease - answerBorrelia burgdorferi
erythema migrans - answerfirst stage of Lyme dz, "bull's eye" rash with clear center
what is second stage of Lyme dz? - answerneurologic- limb numbness, Bell's palsy,
meningitis, encephalitis, cardiac (AV block, myocarditis)
what is third stage of Lyme dz? - answerchronic neurologic impairments and
polyarthritis
only spirochete stains with Giema or Wright stain? - answerBorrelia
microaerobic bugs - answercampylobacter, H. pylori, borrelia burgdorferi
vector of Lyme dz - answerhard bodied deer ticks (Ixodes)
natural reservoir: mouse
(also vector for Babesia)
tx for Lyme dz - answeramoxicillin 30-60 days
if neurologic or cardiac too, use IV ceftriaxone
cause of epidemic relapsing fever & vector - answerBorrelia recurrentis, vector: human
body louse
cause of endemic relapsing fever & vector - answerBorrelia parkeri, hermsii, turicatae
vector: soft-bodied tick
what is the Jarish-Herxheimer rxn? - answerflu-like symptoms immediately after
antibiotics are started due to killed bacteria releasing pyrogens
obligate aerobes - answerNasty Pests Must Breathe
Nocardia, Pseudomonas, Mycobacterium tuberculosis, Bacillus
what drug can suppress the immune system and allow a reaction of TB? - answerTNF-
alpha inhibitors
what part of lung do reactivations of TB usually affect? why? - answerapices; highest
PO2
hot tub folliculitis - answerPseudomonas aeruginosa
