Chapter 08: Antibacterial Drugs That Interfere With Protein Synthesis Introductory Clinical Pharmacology 12th Edition by Susan M Ford

Introductory Clinical Pharmacology 12th Edition by Susan M Ford 1. A client has returned to the clinic for follow-up of an infection which is being treated with an aminoglycoside and reports ringing in the ears and dizziness. When developing this client's plan of care, which nursing diagnosis would be the priority? a. Impaired Comfort b. Altered Thought Process c. Diarrhea d. Injury Risk Answer: D Rationale: The development of ototoxicity would lead the nurse to identify a nursing diagnosis of Injury Risk related to the effects of ototoxicity. Although the client's ringing in the ears could cause discomfort, the priority nursing diagnosis would be Injury Risk. There is no evidence of Impaired Comfort, Altered Thought Process, or Diarrhea. Question Format: Multiple Choice Chapter: 8 Learning Objective: 3 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 101, Nursing Diagnoses 2. A client is receiving iron therapy for anemia. The health care provider has ordered tetracycline for an infection. Which action would be most appropriate for the nurse to do? a. Give the drugs at the same time. b. Give the iron first, then follow with the tetracycline in 30 minutes. c. Separate administration times by 2 hours. d. Withhold the iron until the tetracycline therapy is completed. Answer: C Rationale: Iron therapy can interfere with the absorption of tetracycline. Therefore, the nurse should give the iron 2 hours before or after administering tetracycline. The two drugs should not be given at the same time. Withholding the iron would be inappropriate. Question Format: Multiple Choice Chapter: 8 Learning Objective: 4 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 101, Oral Administration 3. A client is prescribed demeclocycline. The nurse would teach the client to be alert for which signs or symptoms? a. Photosensitivity b. Abdominal pain c. Cramping d. Blood dyscrasias Answer: A Rationale: Demeclocycline causes photosensitivity reactions. Abdominal pain and cramping are adverse reactions of macrolides. Blood dyscrasias are an adverse reaction of lincosamides. Question Format: Multiple Choice Chapter: 8 Learning Objective: 4 Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Teaching/Learning Reference: p. 95, Tetracyclines 4. A client who routinely takes antacids has been prescribed tetracycline. The nurse explains to the client that there is an increased risk of which effect related to this combination? a. Increased risk of bleeding b. Increased action of neuromuscular blocking drugs c. Increased profound respiratory depression d. Decreased absorption of tetracycline Answer: D Rationale: Interaction of antacids with a tetracycline drug causes decreased absorption of tetracycline. Increased action of neuromuscular blocking drugs and increased profound respiratory depression are the result of interaction between neuromuscular blocking drugs and tetracyclines. Increased risk of bleeding is a result of interaction between anticoagulants and tetracyclines. Question Format: Multiple Choice Chapter: 8 Learning Objective: 1 Cognitive Level: Understand Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 95, Tetracyclines 5. A nurse is preparing to administer lincosamide to a client. The nurse should examine the client's record to ensure which contraindication does not apply in this case?