Chapter 12: Antifungal and Anti-parasitic Drugs Introductory Clinical Pharmacology 12th Edition by Susan M Ford

Introductory Clinical Pharmacology 12th Edition by Susan M Ford 1. The nurse determines a teaching session about chloroquine is successful when the client correctly articulates which factor? a. Avoid foods that acidify the urine. b. Take the drug on an empty stomach. c. Increase dosage if dosage missed once. d. Discontinue drug if color of urine changes. Answer: A Rationale: The nurse should educate the client to avoid foods that acidify the urine (cranberries, plums, prunes, meats, cheeses, eggs, fish, and grains), as they may interact with the antimalarial drug and increase excretion and thereby decrease the effectiveness of chloroquine while taking the drug. Taking the drug on an empty stomach is not advisable for antimalarial drugs. The nurse should instruct the client to adhere to the dosage regimen unless instructed otherwise. Yellow or brownish discoloration of the urine during chloroquine treatment is normal; there is no need to discontinue the therapy. Question Format: Multiple Choice Chapter: 12 Learning Objective: 7 Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Teaching/Learning Reference: p. 152, Prophylaxis 2. A client is to receive quinine for malaria. Which factor should the nurse prioritize while providing care if the nurse notes the client is also taking warfarin? a. Quinine absorption is increased. b. Metabolism of quinine is increased. c. The client is at increased risk for bleeding. d. The client's risk for a heart attack is increased. Answer: C Rationale: Combining warfarin with quinine increases the risk of bleeding. There is no risk of increased absorption or increased metabolism and no increased risk of heart attack associated with taking warfarin and quinine. Question Format: Multiple Choice Chapter: 12 Learning Objective: 3 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 152, Prophylaxis 3. A client presents to the urgent care clinic reporting vague lower abdominal pains, upset stomach, and itching around the anus. Which laboratory test will be a priority? a. Stool b. Blood c. Urine d. Saliva Answer: A Rationale: The nurse should obtain stool samples of clients with suspected parasitic infection. There is no need to obtain samples of blood, urine, or saliva in cases of suspected parasitic infection. Question Format: Multiple Choice Chapter: 12 Learning Objective: 4 Cognitive Level: Apply Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 153, Client Receiving an Antiparasitic Drug 4. A client with malaria is prescribed doxycycline. The nurse should include which instructions when teaching the client about the adverse reactions? a. Avoid taking warfarin because it increases the risk of bleeding. b. Avoid exposure to the sun by wearing protective clothing. c. Take the drug with food, or immediately afterward. d. Do not drive or perform other activities requiring alertness. Answer: B Rationale: The nurse should instruct the client to avoid exposure to the sun by wearing protective clothing (e.g., long-sleeved shirts, wide-brimmed hats) and by using sunscreen. Combining warfarin with quinine, not doxycycline, increases the risk of bleeding. Doxycycline should be taken on an empty stomach. Doxycycline does not impair alertness, so the client can drive or perform other activities requiring alertness. Question Format: Multiple Choice Chapter: 12 Learning Objective: 7 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Teaching/Learning Reference: p. 157, Summary Drug Table 5. The nurse is caring for a client diagnosed with amebiasis. When developing the care plan, the nurse will include which activity? a. Take vital signs every 8 hours. b. Freeze any stool samples for testing. c. Avoid foods that acidify the urine. d. Provide the client with small, frequent meals.