REV]
gfI
SIONQUESTI
ONSFORxDI
PLOMA
DI
PLOMACLI
NICALCHEMI
STRY
MCQSECTI
ONA:
20MARKS
1. Whichtestisdoner
out
inel
yonCSF?
a) Ketones
b) Urobil
in
c) pH
d) Glucose
2. Whenr ecei
vingaspeci
meni nt
hel
ab,
thef
oll
owi
ngi
nfor
mat
ionmustbeknownEXCEPT:
a) Ageoft hepat
ient
b) Sexofthepatient
c) Heightofthepati
ent
d) Diagnosisoft
hepatient
3. Theprincipleuponwhi chbl oodglucosei
sdet er
mi nedbychemist
ryanal
yzer
sis:
a) Asat oorandKi ng’
s
b) Benedi ct’
squant i
tat
ive
c) Cli
ni sti
xstri
p
d) Glucoseoxi dize
4. Thetypeofbi li
rubindetectedinurineofajaundicedpati
entis:
a) Bot hdirectandindirectbil
i
rubin
b) Directbili
rubi
nonl y
c) I
ndi rectbil
ir
ubinonly
d) Total bil
ir
ubin
5. Thepresenceofst archgranul
esinstool
maybeani
ndi
cat
ionof
:
a) Overproductionofalkali
nephosphatase
b) Undersecret
ionofamy l
ase
c) Pepsinproductionisverylow
d) Dehydrati
on
6. Methodsforcreati
nineest
imati
onincl
ude:
a) Brown’smethod
b) Creati
nineki
nase
c) Cresophthal
eincomplexi
on(CPC)
d) Jaffe’
salkal
inepicr
ate
7. Whi
choft
hefol
lowingsubst
ancei
sincr
easedi
nGout
?
a) Ur
icaci
d
b) Cr
eati
nine
c) Ur
ea
d) Pr
osphorus9
8. Di
acet
ylmonoximei
susedi
nthedet
ermi
nat
ionof
:
a) Cr
eati
nine
b) Cr
eati
ne
c) Ur
icaci
d
d) Ur
ea
,9. Afl
ameemi ssi
onphot
omet
ermaybeusedi
ntheest
imat
ionoft
hef
oll
owi
nganal
yteEXCEPT:
a) Chlori
des
b) Sodium
c) Potasi
um
d) Li
thium
10.Bence-Jonespr
otei
nsar
ebestdemonstr
atedby
:
a) Albusti
x
b) Boili
nguri
neandobser
vingt
emperat
ure
c) 3%TCA
d) BCG
11.Ser
um al
buminisdeter
minedbyt
hef
oll
owi
ngmet
hod:
a) Br
omocresolgr
een(BCG)
b) 3%TCA
c) Al
busti
x
d) MCuleman’
sreagent
12.C.
S.Fprot
einisnormall
yest i
matedbyt
hef
oll
owi
ngr
eagent
s:
a) Concentr
atedniti
ricaci
d
b) 3%Trichl
oroaceticaci
d
c) Bromocresolgreen(BCG)
d) Al
bustixstr
ips
13.Laborat
orysaf et
ystandar
dsdemandt
hatt
hef
oll
owi
ngwor
dsbewr
it
tencl
ear
lyonabot
tl
econt
aini
ng
Conc.sulphuricaci
d
a) Poi son
b) Fl ammabl e
c) Cor rosiv
e
d) Radi oacti
ve
14.Chemicalanal
ysi
sofur
inei
ncl
udest
hef
oll
owi
ngEXCEPT:
a) pH
b) Protei
n
c) Urobil
i
nogen
d) S.Haematobium
15.Midstr
eam uri
nemustbeanal ysedassoonaspossi blebecause:
a) Mostpatient
sarealwaysinahur rytoatt
endt ootheri
ssues
b) ThepHoft heuri
nechangesi flef
tatroom temperatureforalongti
mebef
oreanal
ysi
s
c) Iti
savitali
nvest
igat
iondonebef oreapatienti
stakent otheat
er
d) Itmayabsorbammoni afr
om t heatmospher eandhencel owerit
spH
16.Benedict
’squali
tat
ivereagentwil
l r
eactposi
ti
vel
ywith:
a) Onlyglucose
b) Glucoseandanyot herreducingsugarsandsubstances
c) Non-sugarreducingsubstancesonly
d) Anyur i
nethathaspr ot
ein
17.Qual
it
ycontr
olsamplesmustbe:-
a) Runonceaweek
b) Runal
ongsidet
hepati
entssampl
eswhenev
ert
hedoct
orquest
ionst
hel
abr
esul
ts
, c) Runal
ongsi
dethet
estsampl
esatall
times
d) Runusi
ngspeci
alr
eagent
ssetasi
deforthi
spur
pose
18.Fal
seposit
ivepr
egnancyr esultsfr
om thelabmaymean:
a) Thepati
entisact
uallypregnant
b) Thepati
entisnotpregnantbuthasbeengi venawrongr
esul
t
c) Thereagent
susedar ev eryspecif
icandaccur
ate
d) Thepati
enthadtakenal otofprot
ein
19.Ur
inewi t
hhi ghspecif
icgr
avi
tymayi
ndi
cat
eanyoft
hef
oll
owi
ngEXCEPT:
a) Contami nati
on
b) Glycosuria
c) Sexoft hepatient
d) Protei
nur i
a
20.Ket
onesinurinear
edetect
edby :
a) Acet
est
b) Al
bustix
c) Cl
ini
sti
x
d) Cl
ini
test
p
SECTIONB: ESSAYQUESTIONS(30MARKS)
a) 1Giv
ent hepat
ient
sureareportas120mg/dl
,conver
tthi
sint
obl
oodur
eani
tr
ogen(BUN)
.
(
N=14, O=16,C=12,H=1) (5marks)
b) If55.
5gmsofCaCl2ar
emadet
o1l
i
tre,
whati
stheconcent
rat
ionoft
hesol
uti
oni
nter
msofmol
ari
ty
andpercent
age(
w/v)
?
(
Ca=40,
Cl=35.
5) (
5mar
ks)
2..Defineanddescr ibether
oleoft
hef
oll
owi
ngi
nquant
it
ati
veanal
yti
cal
met
hods
(a)Blanksolut
ion
(b)Standar
dsol ution
(c)Controlsol
ution
(
d)Ref er
enceranges (10mar
ks)
3.
a) Li
sti
nCORRECTsequence,
thef
ivemai
ncomponent
sofasi
mpl
ecol
ori
met
er
(
5mar
ks)
b) Li
stanyt
hreeadv
ant
agesofqual
i
tycont
rol
inacl
i
nical
chemi
str
ylabor
ator
y
(
5mar
ks)
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
(01)Histology
(1)describethefol
lowingprocessesandgi vethei
rusesi
nhi
stol
ogy
(a)picricaci
d( b)HCL( C)ethanol(d)
paraff
inwax
(2)givetheadv antagesandr easonsoff r
eezzi
ngti
ssues
(3)descr i
betheprocessofdecal cif
icat
ion
(
02)Cl
ini
calchemistr
y
(
1)di
ff
erent
iatebetweent
hef
oll
owi
ng:
-
, (
a)bi
li
verdinandbi l
ir
ubi n
(
b)aci
dandal kal
i
(
c)urobil
inogenandur obil
in
(
2)describethefactorsy ouwoul dconsiderwhil
epur
chasi
nganewequi
pmentf
ort
hel
abor
ator
y
(
3)(a)defi
net heterm anti-coagulant
(b)describefivecoagul antsusedincli
nical
chemi
str
ylabor
ator
y
(
03)Haematol
ogy
(
1)di
ff
erent
iat
ebetweenHbAandHbF
(
2)(
a)descri
beESRi ethesett
ingoft
hetestandi
tsimport
ance
(
b)defi
neanticoagulantanddescr
ibethewor
kingpri
nci
pleofEDTA
(
3)Descr
ibethecyanmet hogl
obinmet
hodofHbest i
mati
on
(
04)
microbiology
(1)di
ff
erentiat
ebetweenexotoxi
nandendot oxin
(
2)descr i
bebloodagariehowitispr
epapar edandit
suses
(3)Amal epat i
entcomplai
nstoacli
nicianofproduci
ngyel
lowdi
schar
gef
rom hi
speni
s.
(
a)suggest sthecausat
iveagent
(
b)descr i
bestepbystephowy ouwoul disol
atetheor
gamism
(
05)bloodt ransfusion
(
1)descr i
beal lthestagesofcompat ibi
li
tyt est(x-match)
(
2)givether easonsbehi ndthewashingofr edbl oodcell
s
(3)(a)descr
ibet hecri
t er
iausedintherecruitmentofpot ent
ialbl
ooddonor
(b)describethepr ecauti
onstakentopr ev enttr
ansmissi
bletr
ansf
usioni
nfect
ions
(
06)
parasi
tol
ogy
(
1)descri
bethef
ormal
-ethermethodofstoolexami
nati
on
(
2)descrj
j
ibet
hehar
mfuleffect
sparasi
tecauseinahost
PRACTI CALS
(01)HISTOLOGY
Youar eprovi
dedwi that i
ssuesecti
ononasl i
de.carr
youtaznstai
ningusingt
heappar
atusandr
eagent
s
providedandgivey ourreport
.NB/gi
veapr ocedureandtherepor
tofyourexami
nat
ion
Spots
(
1)(5)di
amondpen- /mi cr
otomekni f
e--
--
-nameitandgi v
eitsuse
(2)tissuetek-
--
---
-namei tandgiveit
suse
(3)pi cr
icaci
d(yel
lowi ncolour)
--
--
--
namei tandgiveit
suse
(4)chr ol
ofor
m----
---
namei tandgiveitsuse
(02)cli
nicalchemi str
y
Youar epr ovi
dedwi thurnespeci
meni natesttube.Perfor
m adipsti
ckandusethechartpr
ovi
dedt
oread
thereactions.
(a)reportont heabnormali
ti
esobserved-
--
--
--
--
---
--
--
glucoseandprotei
npresent
(b)givethepat hologi
calnat
ureindi
catedbythespor t
--
---
--
-di
abet
esandkidneyimpai
rment
Spot
s
(
1)Winchest
erbott
le-
--
--nameandgi
vei
tsuse
(
2)Univ
ersalbot
tl
e--
--
--
-nameandgiv
eit
suse
gfI
SIONQUESTI
ONSFORxDI
PLOMA
DI
PLOMACLI
NICALCHEMI
STRY
MCQSECTI
ONA:
20MARKS
1. Whichtestisdoner
out
inel
yonCSF?
a) Ketones
b) Urobil
in
c) pH
d) Glucose
2. Whenr ecei
vingaspeci
meni nt
hel
ab,
thef
oll
owi
ngi
nfor
mat
ionmustbeknownEXCEPT:
a) Ageoft hepat
ient
b) Sexofthepatient
c) Heightofthepati
ent
d) Diagnosisoft
hepatient
3. Theprincipleuponwhi chbl oodglucosei
sdet er
mi nedbychemist
ryanal
yzer
sis:
a) Asat oorandKi ng’
s
b) Benedi ct’
squant i
tat
ive
c) Cli
ni sti
xstri
p
d) Glucoseoxi dize
4. Thetypeofbi li
rubindetectedinurineofajaundicedpati
entis:
a) Bot hdirectandindirectbil
i
rubin
b) Directbili
rubi
nonl y
c) I
ndi rectbil
ir
ubinonly
d) Total bil
ir
ubin
5. Thepresenceofst archgranul
esinstool
maybeani
ndi
cat
ionof
:
a) Overproductionofalkali
nephosphatase
b) Undersecret
ionofamy l
ase
c) Pepsinproductionisverylow
d) Dehydrati
on
6. Methodsforcreati
nineest
imati
onincl
ude:
a) Brown’smethod
b) Creati
nineki
nase
c) Cresophthal
eincomplexi
on(CPC)
d) Jaffe’
salkal
inepicr
ate
7. Whi
choft
hefol
lowingsubst
ancei
sincr
easedi
nGout
?
a) Ur
icaci
d
b) Cr
eati
nine
c) Ur
ea
d) Pr
osphorus9
8. Di
acet
ylmonoximei
susedi
nthedet
ermi
nat
ionof
:
a) Cr
eati
nine
b) Cr
eati
ne
c) Ur
icaci
d
d) Ur
ea
,9. Afl
ameemi ssi
onphot
omet
ermaybeusedi
ntheest
imat
ionoft
hef
oll
owi
nganal
yteEXCEPT:
a) Chlori
des
b) Sodium
c) Potasi
um
d) Li
thium
10.Bence-Jonespr
otei
nsar
ebestdemonstr
atedby
:
a) Albusti
x
b) Boili
nguri
neandobser
vingt
emperat
ure
c) 3%TCA
d) BCG
11.Ser
um al
buminisdeter
minedbyt
hef
oll
owi
ngmet
hod:
a) Br
omocresolgr
een(BCG)
b) 3%TCA
c) Al
busti
x
d) MCuleman’
sreagent
12.C.
S.Fprot
einisnormall
yest i
matedbyt
hef
oll
owi
ngr
eagent
s:
a) Concentr
atedniti
ricaci
d
b) 3%Trichl
oroaceticaci
d
c) Bromocresolgreen(BCG)
d) Al
bustixstr
ips
13.Laborat
orysaf et
ystandar
dsdemandt
hatt
hef
oll
owi
ngwor
dsbewr
it
tencl
ear
lyonabot
tl
econt
aini
ng
Conc.sulphuricaci
d
a) Poi son
b) Fl ammabl e
c) Cor rosiv
e
d) Radi oacti
ve
14.Chemicalanal
ysi
sofur
inei
ncl
udest
hef
oll
owi
ngEXCEPT:
a) pH
b) Protei
n
c) Urobil
i
nogen
d) S.Haematobium
15.Midstr
eam uri
nemustbeanal ysedassoonaspossi blebecause:
a) Mostpatient
sarealwaysinahur rytoatt
endt ootheri
ssues
b) ThepHoft heuri
nechangesi flef
tatroom temperatureforalongti
mebef
oreanal
ysi
s
c) Iti
savitali
nvest
igat
iondonebef oreapatienti
stakent otheat
er
d) Itmayabsorbammoni afr
om t heatmospher eandhencel owerit
spH
16.Benedict
’squali
tat
ivereagentwil
l r
eactposi
ti
vel
ywith:
a) Onlyglucose
b) Glucoseandanyot herreducingsugarsandsubstances
c) Non-sugarreducingsubstancesonly
d) Anyur i
nethathaspr ot
ein
17.Qual
it
ycontr
olsamplesmustbe:-
a) Runonceaweek
b) Runal
ongsidet
hepati
entssampl
eswhenev
ert
hedoct
orquest
ionst
hel
abr
esul
ts
, c) Runal
ongsi
dethet
estsampl
esatall
times
d) Runusi
ngspeci
alr
eagent
ssetasi
deforthi
spur
pose
18.Fal
seposit
ivepr
egnancyr esultsfr
om thelabmaymean:
a) Thepati
entisact
uallypregnant
b) Thepati
entisnotpregnantbuthasbeengi venawrongr
esul
t
c) Thereagent
susedar ev eryspecif
icandaccur
ate
d) Thepati
enthadtakenal otofprot
ein
19.Ur
inewi t
hhi ghspecif
icgr
avi
tymayi
ndi
cat
eanyoft
hef
oll
owi
ngEXCEPT:
a) Contami nati
on
b) Glycosuria
c) Sexoft hepatient
d) Protei
nur i
a
20.Ket
onesinurinear
edetect
edby :
a) Acet
est
b) Al
bustix
c) Cl
ini
sti
x
d) Cl
ini
test
p
SECTIONB: ESSAYQUESTIONS(30MARKS)
a) 1Giv
ent hepat
ient
sureareportas120mg/dl
,conver
tthi
sint
obl
oodur
eani
tr
ogen(BUN)
.
(
N=14, O=16,C=12,H=1) (5marks)
b) If55.
5gmsofCaCl2ar
emadet
o1l
i
tre,
whati
stheconcent
rat
ionoft
hesol
uti
oni
nter
msofmol
ari
ty
andpercent
age(
w/v)
?
(
Ca=40,
Cl=35.
5) (
5mar
ks)
2..Defineanddescr ibether
oleoft
hef
oll
owi
ngi
nquant
it
ati
veanal
yti
cal
met
hods
(a)Blanksolut
ion
(b)Standar
dsol ution
(c)Controlsol
ution
(
d)Ref er
enceranges (10mar
ks)
3.
a) Li
sti
nCORRECTsequence,
thef
ivemai
ncomponent
sofasi
mpl
ecol
ori
met
er
(
5mar
ks)
b) Li
stanyt
hreeadv
ant
agesofqual
i
tycont
rol
inacl
i
nical
chemi
str
ylabor
ator
y
(
5mar
ks)
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
(01)Histology
(1)describethefol
lowingprocessesandgi vethei
rusesi
nhi
stol
ogy
(a)picricaci
d( b)HCL( C)ethanol(d)
paraff
inwax
(2)givetheadv antagesandr easonsoff r
eezzi
ngti
ssues
(3)descr i
betheprocessofdecal cif
icat
ion
(
02)Cl
ini
calchemistr
y
(
1)di
ff
erent
iatebetweent
hef
oll
owi
ng:
-
, (
a)bi
li
verdinandbi l
ir
ubi n
(
b)aci
dandal kal
i
(
c)urobil
inogenandur obil
in
(
2)describethefactorsy ouwoul dconsiderwhil
epur
chasi
nganewequi
pmentf
ort
hel
abor
ator
y
(
3)(a)defi
net heterm anti-coagulant
(b)describefivecoagul antsusedincli
nical
chemi
str
ylabor
ator
y
(
03)Haematol
ogy
(
1)di
ff
erent
iat
ebetweenHbAandHbF
(
2)(
a)descri
beESRi ethesett
ingoft
hetestandi
tsimport
ance
(
b)defi
neanticoagulantanddescr
ibethewor
kingpri
nci
pleofEDTA
(
3)Descr
ibethecyanmet hogl
obinmet
hodofHbest i
mati
on
(
04)
microbiology
(1)di
ff
erentiat
ebetweenexotoxi
nandendot oxin
(
2)descr i
bebloodagariehowitispr
epapar edandit
suses
(3)Amal epat i
entcomplai
nstoacli
nicianofproduci
ngyel
lowdi
schar
gef
rom hi
speni
s.
(
a)suggest sthecausat
iveagent
(
b)descr i
bestepbystephowy ouwoul disol
atetheor
gamism
(
05)bloodt ransfusion
(
1)descr i
beal lthestagesofcompat ibi
li
tyt est(x-match)
(
2)givether easonsbehi ndthewashingofr edbl oodcell
s
(3)(a)descr
ibet hecri
t er
iausedintherecruitmentofpot ent
ialbl
ooddonor
(b)describethepr ecauti
onstakentopr ev enttr
ansmissi
bletr
ansf
usioni
nfect
ions
(
06)
parasi
tol
ogy
(
1)descri
bethef
ormal
-ethermethodofstoolexami
nati
on
(
2)descrj
j
ibet
hehar
mfuleffect
sparasi
tecauseinahost
PRACTI CALS
(01)HISTOLOGY
Youar eprovi
dedwi that i
ssuesecti
ononasl i
de.carr
youtaznstai
ningusingt
heappar
atusandr
eagent
s
providedandgivey ourreport
.NB/gi
veapr ocedureandtherepor
tofyourexami
nat
ion
Spots
(
1)(5)di
amondpen- /mi cr
otomekni f
e--
--
-nameitandgi v
eitsuse
(2)tissuetek-
--
---
-namei tandgiveit
suse
(3)pi cr
icaci
d(yel
lowi ncolour)
--
--
--
namei tandgiveit
suse
(4)chr ol
ofor
m----
---
namei tandgiveitsuse
(02)cli
nicalchemi str
y
Youar epr ovi
dedwi thurnespeci
meni natesttube.Perfor
m adipsti
ckandusethechartpr
ovi
dedt
oread
thereactions.
(a)reportont heabnormali
ti
esobserved-
--
--
--
--
---
--
--
glucoseandprotei
npresent
(b)givethepat hologi
calnat
ureindi
catedbythespor t
--
---
--
-di
abet
esandkidneyimpai
rment
Spot
s
(
1)Winchest
erbott
le-
--
--nameandgi
vei
tsuse
(
2)Univ
ersalbot
tl
e--
--
--
-nameandgiv
eit
suse
