(MCM 1202)
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
MEDICAL SCHOOL
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 1 EXAMINATIONS
(MCM 1202) : HUMAN GENETICS
DATE : DECEMBER 2005
TIME : 3 HOURS
Instructions to Candidates
1) Answer all questions
SECTION A
1. Discuss the causes and consequences of aneuploidy in humans with
emphasis on the clinical implications. (20)
2. Write an essay on point mutations. (20)
SECTION B
1. In a family of 3 boys and 3 girls, two boys had hemophilia phenotype.
a) Did they inherit the condition from the mother or father or from both
parents? (3)
b) Is the boy without hemophilia likely to be carrying its genotype? (2)
c) Do the girls have a higher probability of carrying the hemophilia
genotype. (3)
d) If one more girl was born into the family could she possibly be
hemophilic? (3)
Page 1 of 2
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
MEDICAL SCHOOL
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 1 EXAMINATIONS
(MCM 1202) : HUMAN GENETICS
DATE : DECEMBER 2005
TIME : 3 HOURS
Instructions to Candidates
1) Answer all questions
SECTION A
1. Discuss the causes and consequences of aneuploidy in humans with
emphasis on the clinical implications. (20)
2. Write an essay on point mutations. (20)
SECTION B
1. In a family of 3 boys and 3 girls, two boys had hemophilia phenotype.
a) Did they inherit the condition from the mother or father or from both
parents? (3)
b) Is the boy without hemophilia likely to be carrying its genotype? (2)
c) Do the girls have a higher probability of carrying the hemophilia
genotype. (3)
d) If one more girl was born into the family could she possibly be
hemophilic? (3)
Page 1 of 2
