MBM 2101
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 2 EXAMINATIONS
MBM 2101 : SYNTHESIS OF BIOMOLECULES
DATE : DECEMBER 2006
TIME : 3 HOURS
Instructions to Candidates
Answer all questions
SECTION A
1. Clearly outline the hexose monophosphate shunt, highlight its significance and
the associated disorders. (20)
2. Give a detailed account of cholesterol synthesis and its regulation. (20)
______________________________________________________________________
SECTION B
3. How is glucose formed from the following:
(a) galactose (3)
(b) fructose (3)
4. How does fructose 2,6 bisphosphate regulate gluconeogenesis? (4)
5. Write short notes on the following
(a) von Gierke’s disease (3)
(b) Pompe’s disease. (3)
6. Highlight the differences between glycogen metabolism in red muscle and white
muscle. (4)
Page 1 of 1
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 2 EXAMINATIONS
MBM 2101 : SYNTHESIS OF BIOMOLECULES
DATE : DECEMBER 2006
TIME : 3 HOURS
Instructions to Candidates
Answer all questions
SECTION A
1. Clearly outline the hexose monophosphate shunt, highlight its significance and
the associated disorders. (20)
2. Give a detailed account of cholesterol synthesis and its regulation. (20)
______________________________________________________________________
SECTION B
3. How is glucose formed from the following:
(a) galactose (3)
(b) fructose (3)
4. How does fructose 2,6 bisphosphate regulate gluconeogenesis? (4)
5. Write short notes on the following
(a) von Gierke’s disease (3)
(b) Pompe’s disease. (3)
6. Highlight the differences between glycogen metabolism in red muscle and white
muscle. (4)
Page 1 of 1
