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Human Genetics

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Exam of 2 pages for the course Basic Medical Sciences at Basic Medical Sciences (Human Geneticsexam)

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Basic Medical Sciences
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MBM 1202


NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY

FACULTY OF MEDICINE

BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 1 EXAMINATIONS

MBM 1202 : HUMAN GENETICS

DATE : MAY 2006

TIME : 3 HOURS


Instructions to Candidates

Answer all questions


SECTION A

1. Write an essay on sex determination in humans and other animals. (20)

2. Write an essay on chromosomal aberrations in humans. (20)



SECTION B

1. (a) How is DNA sequencing performed using the Maxam-Gilbert method? (8)

(b) What are the consequences of trisomy in humans? (8)

2. Write notes on the following:

(a) RFLP (5)
(b) gene mapping. (5)

3. Describe the following phenomena:

(a) epistasis (4)
(b) Rh factor inheritance (4)
(c) pleiotropy (4)
(d) G-banding (4)




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