MBM 1201
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 1 EXAMINATIONS (SUPP)
MBM 1201 : DIGESTION AND NUTRIENT METABOLISM
DATE : JULY 2006
TIME : 3 HOURS
Instructions to Candidates
Answer all questions
SECTION A
1. Describe the various anaplerotic reactions that replenish the TCA cycle. Why are
these reactions necessary? (20)
2. Write an essay on bile secretion, its control and intestinal absorption. Highlight
why high levels of cholesterol in bile result in cholesterol gallstone formation.
(20)
SECTION B
3. With reference to oxidative phosphorylation, explain the following terms:
(i) P:0 ratio (2)
(ii) uncoupling (2)
(iii) chemiosmosis (2)
(iv) the redox potential (2)
(v) the proton motive force. (2)
4. Differentiate between substrate level phosphorylation and oxidative
phosphorylation. (3)
Page 1 of 1
NATIONAL UNIVERISTY OF SCIENCE AND TECHNOLOGY
FACULTY OF MEDICINE
BACHELOR OF MEDICINE AND BACHELOR OF SURGERY DEGREE
PART 1 EXAMINATIONS (SUPP)
MBM 1201 : DIGESTION AND NUTRIENT METABOLISM
DATE : JULY 2006
TIME : 3 HOURS
Instructions to Candidates
Answer all questions
SECTION A
1. Describe the various anaplerotic reactions that replenish the TCA cycle. Why are
these reactions necessary? (20)
2. Write an essay on bile secretion, its control and intestinal absorption. Highlight
why high levels of cholesterol in bile result in cholesterol gallstone formation.
(20)
SECTION B
3. With reference to oxidative phosphorylation, explain the following terms:
(i) P:0 ratio (2)
(ii) uncoupling (2)
(iii) chemiosmosis (2)
(iv) the redox potential (2)
(v) the proton motive force. (2)
4. Differentiate between substrate level phosphorylation and oxidative
phosphorylation. (3)
Page 1 of 1
