Describe the use of antipsychotic drugs as a method of modifying schizophrenia. 10 marks
Point
What are - A form of drug therapy that is used to treat the symptoms of schizophrenia. Aim to treat
antipsychotic both the positive such as hallucinations and negative such as poverty of speech.
drugs - Can be given in liquid and tablet form
- 2 types conventional and a typical (the most recent)
What are - These were the first type of antipsychotics that were created, may be referred to as
conventional neuroleptics.
drugs and how - Created in the 1950’s
do they work - Bind to dopamine 2 receptor cells and perform antagonist action in order to reduce the
activity and release of dopamine 2.
- Have a 48-hour bind time.
- Reduce positive symptoms of schizophrenia.
- E.g hallucinations and delusions
What are a - These are the recent form of antipsychotic drugs, they have a shorter bind time of 24 hours
typical drugs - They perform agonist action on d1 receptors as well as antagonist action on d2 receptor
and how do cells
they work - Can be used to reduce both positive and negative symptoms.
- E.g poverty of speech or social withdrawal
- Also have action on serotonin 1-5 HTA’s receptors
- They have a shorter half-life compared to conventional.
- Not as widely used as conventional drugs
Phenothiazine - Is an example of a conventional neuroleptic that is used to treat schizophrenia?
example - Found to be 75% effective at reducing positive symtpoms of schizophrenia.
Point
What are - A form of drug therapy that is used to treat the symptoms of schizophrenia. Aim to treat
antipsychotic both the positive such as hallucinations and negative such as poverty of speech.
drugs - Can be given in liquid and tablet form
- 2 types conventional and a typical (the most recent)
What are - These were the first type of antipsychotics that were created, may be referred to as
conventional neuroleptics.
drugs and how - Created in the 1950’s
do they work - Bind to dopamine 2 receptor cells and perform antagonist action in order to reduce the
activity and release of dopamine 2.
- Have a 48-hour bind time.
- Reduce positive symptoms of schizophrenia.
- E.g hallucinations and delusions
What are a - These are the recent form of antipsychotic drugs, they have a shorter bind time of 24 hours
typical drugs - They perform agonist action on d1 receptors as well as antagonist action on d2 receptor
and how do cells
they work - Can be used to reduce both positive and negative symptoms.
- E.g poverty of speech or social withdrawal
- Also have action on serotonin 1-5 HTA’s receptors
- They have a shorter half-life compared to conventional.
- Not as widely used as conventional drugs
Phenothiazine - Is an example of a conventional neuroleptic that is used to treat schizophrenia?
example - Found to be 75% effective at reducing positive symtpoms of schizophrenia.
