Nuclear Oncology NMTCB Review Exam With Complete
Solution
What is Ga-67 citrate most commonly used for in tumor imaging?
Detection of lymphoma to assess the extent of the disease and its progression, also to
monitor the patients response to treatment
(Lung cancer and multiple myeloma also concentrate in this tracer)
What patient preparation is used for Ga-67 citrate imaging?
Oral laxatives or enams may be used for bowel prep, recent iron therapy, or gadolinium
magnetic resonance contrast agents, areas of recent trauma or infection
What is the dose for Ga-67 tumor imaging?
5-10 mCi Ga-67 citrate
How do you image for Ga-67 citrate tumor imaging?
48-72 hours post tracer administration, ANT and POST images of head, chest, and
abdomen and acquired using spot-view or WB technique
- Delayed images beyond 72 hours may be necessary
How does In-111 Pentetreotide (Octreoscan) work?
Analog of the hormone somatostatine, which binds to the somatostatin receptors on the
surface of cells concentrating in tumors with a hgih density of receptor sites
What is somatotostatin?
It is a hormones that functions include neurotransmission, inhibition of the release of
growth hormone, insuline, glucagon, and gastrin, also a hormone production by certain
types of tumors
- concentrated in the hypothalamus, cerebral cortex, brain stem, GI tracer, and
pancreas
Where are receptor sites for somatostatin located?
anterior pituitary gland, pancreatic islet cells, lymphocytes, and tumors (brain, breast,
lung cancer, and melanoma)
What types of. tumors does In-111 pentriotide (octreoscan) help to image?
pituitary, endocrine, paraganglioma, medullary thyroid carcinoma, carcinoids and small
cell lung cancer, (neuroendocrine tumors)
Solution
What is Ga-67 citrate most commonly used for in tumor imaging?
Detection of lymphoma to assess the extent of the disease and its progression, also to
monitor the patients response to treatment
(Lung cancer and multiple myeloma also concentrate in this tracer)
What patient preparation is used for Ga-67 citrate imaging?
Oral laxatives or enams may be used for bowel prep, recent iron therapy, or gadolinium
magnetic resonance contrast agents, areas of recent trauma or infection
What is the dose for Ga-67 tumor imaging?
5-10 mCi Ga-67 citrate
How do you image for Ga-67 citrate tumor imaging?
48-72 hours post tracer administration, ANT and POST images of head, chest, and
abdomen and acquired using spot-view or WB technique
- Delayed images beyond 72 hours may be necessary
How does In-111 Pentetreotide (Octreoscan) work?
Analog of the hormone somatostatine, which binds to the somatostatin receptors on the
surface of cells concentrating in tumors with a hgih density of receptor sites
What is somatotostatin?
It is a hormones that functions include neurotransmission, inhibition of the release of
growth hormone, insuline, glucagon, and gastrin, also a hormone production by certain
types of tumors
- concentrated in the hypothalamus, cerebral cortex, brain stem, GI tracer, and
pancreas
Where are receptor sites for somatostatin located?
anterior pituitary gland, pancreatic islet cells, lymphocytes, and tumors (brain, breast,
lung cancer, and melanoma)
What types of. tumors does In-111 pentriotide (octreoscan) help to image?
pituitary, endocrine, paraganglioma, medullary thyroid carcinoma, carcinoids and small
cell lung cancer, (neuroendocrine tumors)
