Biochemistry Exam 2 Guide 2024

are mostly carbohydrate by weight. The carbohydrate portion is branched and complex - Correct Answer Mucins are mostly carbohydrate by weight. The carbohydrate portion consists of repeating disaccharide units. - Correct Answer proteoglycans the membrane proteins that contain blood group antigens are examples of? - Correct Answer Glycoproteins Attraction of water molecules is vital tot he functions of ______ and ______ - Correct Answer Mucins and proteoglycans Cholesterol is an important modulator of membrane fluidity in animals. i.) Describe the effect of cholesterol on fluidity at temperatures below the Tm of the membrane. Include the structural basis of this effect in your answer. - Correct Answer Makes less gel-like (more fluid) by wedging between non polar tails and disrupting van der Waals interactions Describe the effect of cholesterol on fluidity at temperatures above the Tm of the membrane. Include the structural basis of this effect in your answer. - Correct Answer makes less liquid-like (less fluid) by filling in gaps between nonpolar tails, reducing movement of fatty acid chains Fetal hemoglobin - Correct Answer has lower affinity for 2,3-bisphosphoglycerate than adult hemoglobin which decreases its P50 for oxygen binding For myoglobin binding to oxygen, when pO2 is much, much greater than P50, Y = - Correct Answer 1 What would be the expected result of mutations in the β subunits of hemoglobin that replaced lysine and histidine residues with aspartate and glutamate residues in the 2,3- Bisphosphoglycerate binding site? - Correct Answer 2,3-BPG would bind less tightly because of the loss of positive charges The carbohydrate portion of membrane glycolipids and glycoproteins is almost always - Correct Answer on the extracellular side of the membrane