UNE BioChem 1005 Final Exam Questions & Answers
Solved 100% Correct!!
Somatostatin reduces the secretion of both glucagon and insulin through which
of the following mechanisms?
a. Somatostatin activates an activator G-protein
b. Somatostatin activates MAPK cascade
c. Somatostatin activates an inhibitory G-protein
d. Somatostatin uses Ca+2 as a downstream signal
c. Somatostatin activates an inhibitory G-protein
Insulin mediated glucose uptake by muscle and adipose tissue is a result of
which of the following mechanisms?
a. Translocation of GLUT 4 receptors to the cell surface
b. Translocation of GLUT 1 (Na+/K+ symporter) to the cell surface
c. Passive diffusion
d. Activation of protein kinase A
a. Translocation of GLUT 4 receptors to the cell surface
The alanine - glucose cycle is primarily used for which of the following purposes?
a. To move ammonia from skeletal muscle to the liver
b. To generate ATP for the skeletal muscle
c. To move glucose from the skeletal muscle to the liver
d. To move alanine from the liver to the skeletal muscle
a. To move ammonia from skeletal muscle to the liver
Which statement best illustrates an example of post translational gene
regulation?
a. Protein kinase A mediated phosphorylation of glycogen phosphorylase
b. Cortisol binds a cytosolic receptor, translocates to the nucleus and binds a
GRE
c. Iron binding the iron response elements binding protein (IRE_BP) allowing for
translation of ferritin mRNA
d. DNA histone associations leading to super-coiling of DNA
a. Protein kinase A mediated phosphorylation of glycogen phosphorylase
Which of the following hormones is released from the liver in response to
increased levels of growth hormone?
a. Cortisol
b. Thyroid hormone
c. Somatostatin
d. Insulin-like growth factor (IGF)
d. Insulin-like growth factor (IGF)
, Autophagy is process involves degradation of protein. Under conditions of high
energy (HIGH ATP) which of the following is true regarding regulation of this
process?
a. Akt is inactive
b. AMPK is actice and phosphorylates TSC1/TSC2 Complex
c. mTOR is activated
d. Rheb is bound to GDP
c. mTOR is activated
Synthesis of which of the following lipoproteins would be elevated after a
carbohydrate rich meal?
a. HDL
b. Chylomicrons
c. LDL
d. VLDL
d. VLDL
The synthesis of N-acetylglutamate (NAGS) is required for the activity of the urea
cycle. This compound stimulates the activity of which of the following enzymes?
a. Arginase
b. Carbamoyl phosphate synthetase I (CPSI)
c. Ornithine transcarbamoylase
d. Carbamoyl phosphate synthetase II (CPSII)
b. Carbamoyl phosphate synthetase I (CPSI)
A male infant starts to show signs of lethargy rapidly after birth. Upon evaluation
he is determined to have a deficiency in n-acetylglutamate synthesis. Based on
this information, which of the following would consistent with this diagnosis?
a. Elevated levels of arginine
b. Decreased levels of carbamoyl phosphate
c. Decreased levels of ammonia
d. Elevated levels of citrulline
b. Decreased levels of carbamoyl phosphate
Which of the following individuals would most likely be in a positive nitrogen
balance?
a. An elderly individual with pneumonia
b. A 10-year old boy after he fell out of a tree and broke his arm
c. A healthy female in the third trimester of pregnancy
c. A healthy female in the third trimester of pregnancy
Glucose cannot be synthesized from the β-oxidation of even chain fatty acids
because:
a. gluconeogenesis is inhibited by acetyl CoA produced in the β-oxidation of fatty
acids
Solved 100% Correct!!
Somatostatin reduces the secretion of both glucagon and insulin through which
of the following mechanisms?
a. Somatostatin activates an activator G-protein
b. Somatostatin activates MAPK cascade
c. Somatostatin activates an inhibitory G-protein
d. Somatostatin uses Ca+2 as a downstream signal
c. Somatostatin activates an inhibitory G-protein
Insulin mediated glucose uptake by muscle and adipose tissue is a result of
which of the following mechanisms?
a. Translocation of GLUT 4 receptors to the cell surface
b. Translocation of GLUT 1 (Na+/K+ symporter) to the cell surface
c. Passive diffusion
d. Activation of protein kinase A
a. Translocation of GLUT 4 receptors to the cell surface
The alanine - glucose cycle is primarily used for which of the following purposes?
a. To move ammonia from skeletal muscle to the liver
b. To generate ATP for the skeletal muscle
c. To move glucose from the skeletal muscle to the liver
d. To move alanine from the liver to the skeletal muscle
a. To move ammonia from skeletal muscle to the liver
Which statement best illustrates an example of post translational gene
regulation?
a. Protein kinase A mediated phosphorylation of glycogen phosphorylase
b. Cortisol binds a cytosolic receptor, translocates to the nucleus and binds a
GRE
c. Iron binding the iron response elements binding protein (IRE_BP) allowing for
translation of ferritin mRNA
d. DNA histone associations leading to super-coiling of DNA
a. Protein kinase A mediated phosphorylation of glycogen phosphorylase
Which of the following hormones is released from the liver in response to
increased levels of growth hormone?
a. Cortisol
b. Thyroid hormone
c. Somatostatin
d. Insulin-like growth factor (IGF)
d. Insulin-like growth factor (IGF)
, Autophagy is process involves degradation of protein. Under conditions of high
energy (HIGH ATP) which of the following is true regarding regulation of this
process?
a. Akt is inactive
b. AMPK is actice and phosphorylates TSC1/TSC2 Complex
c. mTOR is activated
d. Rheb is bound to GDP
c. mTOR is activated
Synthesis of which of the following lipoproteins would be elevated after a
carbohydrate rich meal?
a. HDL
b. Chylomicrons
c. LDL
d. VLDL
d. VLDL
The synthesis of N-acetylglutamate (NAGS) is required for the activity of the urea
cycle. This compound stimulates the activity of which of the following enzymes?
a. Arginase
b. Carbamoyl phosphate synthetase I (CPSI)
c. Ornithine transcarbamoylase
d. Carbamoyl phosphate synthetase II (CPSII)
b. Carbamoyl phosphate synthetase I (CPSI)
A male infant starts to show signs of lethargy rapidly after birth. Upon evaluation
he is determined to have a deficiency in n-acetylglutamate synthesis. Based on
this information, which of the following would consistent with this diagnosis?
a. Elevated levels of arginine
b. Decreased levels of carbamoyl phosphate
c. Decreased levels of ammonia
d. Elevated levels of citrulline
b. Decreased levels of carbamoyl phosphate
Which of the following individuals would most likely be in a positive nitrogen
balance?
a. An elderly individual with pneumonia
b. A 10-year old boy after he fell out of a tree and broke his arm
c. A healthy female in the third trimester of pregnancy
c. A healthy female in the third trimester of pregnancy
Glucose cannot be synthesized from the β-oxidation of even chain fatty acids
because:
a. gluconeogenesis is inhibited by acetyl CoA produced in the β-oxidation of fatty
acids
