UNE Biochem Unit 2 Exam Quizzes & Answers
Glycolysis provides intermediates that can be used to make other necessary
substrates. One example of this is the direct conversion of pyruvate to which of
the following amino acids?
a. proline
b. threonine
c. glutamate
d. alanine
alanine
Which of the following best describes the net effect of the 8 steps of the TCA
cycle?
a. this process completely oxidizes an acetyl group to carbon dioxide
b. this process directly converts pyruvate to succinate
c. this process produces NAD+ and Q
d. this process directly produces ATP for the cell
this process completely oxidizes an acetyl group to carbon dioxide
Pyruvate dehydrogenase complex is highly regulated. The enzyme will be most
active when which of the following compounds is high?
a. pyruvate
b. acetyl-CoA
c. NADH
d. malate
pyruvate
After a meal, Fructose 2, 6 bisphosphate levels are elevated. This compound will
allosterically activate which of the following glycolytic enzymes?
a. phosphofructokinase-1 (PFK1)
b. phosphofructokinase-2 (PFK2)
c. hexokinase
d. glycogen synthase
phosphofructokinase-1 (PFK1)
A 10-year old girl is swimming in a local competition. The intense exercise will
increase intracellular calcium which will increase flux through the TCA cycle by
stimulating the activity of all of the following enzymes except?
a. pyruvate dehydrogenase complex
b. alpha-ketoglutarate dehydrogenase
c. isocitrate dehydrogenase
d. succiante thiokinase
succinate thiokinase
TCA cycle intermediates are always being removed for various reasons but the
cycle doesn't run out of intermediates and stop. This is because the TCA cycle
can replenish intermediates through which of the following?
a. from even chain fatty acids
b. using anaplerotic reactions
c. from acetyl CoA
d. from the catabolism of heme in the spleen
, using anaplerotic reactions
Which of the following enzymes is correctly paired with its activator?
a. isocitrate dehydrogenase; NADH
b. pyruvate dehydrogenase complex; pyruvate
c. glyceraldehyde 3-phosphate dehydrogenase; citrate
d. pyruvate kinase; citrate
pyruvate dehydrogenase complex; pyruvate
Which of the following reactions is commonly used to replenish intermediates of
the TCA cycle?
a. citrate to oxaloacetate and acetyl CoA
b. glutamate to alpha-ketoglutarate
c. oxaloacetate to aspartate
d. pyruvate to alanine
glutamate to alpha-ketoglutarate
A patient is newly diagnosed with a deficiency in fructokinase. Which of the
following will not be a metabolic consequence of this deficiency?
a. the presence of reducing sugar in the urine
b. hypoglycemia
c. decrease in fructose-1-phosphate
d. inability to metabolize fructose
hypoglycemia
Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and
glyceraldehyde 3-phosphate is facilitated by which enzyme?
a. fructohydrolase
b. ketolase
c. aldolase
d. fructokinase
aldolase
Aldolase B facilitates a reaction that cleaves fructose-1-phosphate into two 3-
carbon molecules that will enter glycolysis as which of the following
compounds?
a. glyceraldehyde-3-phosphate
b. acetyl CoA
c. glucose 6-phosphate
d. lactate
glyceraldehyde 3 phosphate
Which of the following cofactors is required for transketolase activity?
a. biotin
b. thiamine diphosphate
c. pyridoxal phosphate
d. NAD+
thiamine diphosphate
A family presents for genetic counseling. The couple has 2 female children who
are alive and well; however, their infant son recently died in the nursery with
severe hemolysis and jaundice. The wife recalls she lost a brother in infancy with
severe hemolysis. The physician suspects a glucose-6-phosphate
Glycolysis provides intermediates that can be used to make other necessary
substrates. One example of this is the direct conversion of pyruvate to which of
the following amino acids?
a. proline
b. threonine
c. glutamate
d. alanine
alanine
Which of the following best describes the net effect of the 8 steps of the TCA
cycle?
a. this process completely oxidizes an acetyl group to carbon dioxide
b. this process directly converts pyruvate to succinate
c. this process produces NAD+ and Q
d. this process directly produces ATP for the cell
this process completely oxidizes an acetyl group to carbon dioxide
Pyruvate dehydrogenase complex is highly regulated. The enzyme will be most
active when which of the following compounds is high?
a. pyruvate
b. acetyl-CoA
c. NADH
d. malate
pyruvate
After a meal, Fructose 2, 6 bisphosphate levels are elevated. This compound will
allosterically activate which of the following glycolytic enzymes?
a. phosphofructokinase-1 (PFK1)
b. phosphofructokinase-2 (PFK2)
c. hexokinase
d. glycogen synthase
phosphofructokinase-1 (PFK1)
A 10-year old girl is swimming in a local competition. The intense exercise will
increase intracellular calcium which will increase flux through the TCA cycle by
stimulating the activity of all of the following enzymes except?
a. pyruvate dehydrogenase complex
b. alpha-ketoglutarate dehydrogenase
c. isocitrate dehydrogenase
d. succiante thiokinase
succinate thiokinase
TCA cycle intermediates are always being removed for various reasons but the
cycle doesn't run out of intermediates and stop. This is because the TCA cycle
can replenish intermediates through which of the following?
a. from even chain fatty acids
b. using anaplerotic reactions
c. from acetyl CoA
d. from the catabolism of heme in the spleen
, using anaplerotic reactions
Which of the following enzymes is correctly paired with its activator?
a. isocitrate dehydrogenase; NADH
b. pyruvate dehydrogenase complex; pyruvate
c. glyceraldehyde 3-phosphate dehydrogenase; citrate
d. pyruvate kinase; citrate
pyruvate dehydrogenase complex; pyruvate
Which of the following reactions is commonly used to replenish intermediates of
the TCA cycle?
a. citrate to oxaloacetate and acetyl CoA
b. glutamate to alpha-ketoglutarate
c. oxaloacetate to aspartate
d. pyruvate to alanine
glutamate to alpha-ketoglutarate
A patient is newly diagnosed with a deficiency in fructokinase. Which of the
following will not be a metabolic consequence of this deficiency?
a. the presence of reducing sugar in the urine
b. hypoglycemia
c. decrease in fructose-1-phosphate
d. inability to metabolize fructose
hypoglycemia
Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and
glyceraldehyde 3-phosphate is facilitated by which enzyme?
a. fructohydrolase
b. ketolase
c. aldolase
d. fructokinase
aldolase
Aldolase B facilitates a reaction that cleaves fructose-1-phosphate into two 3-
carbon molecules that will enter glycolysis as which of the following
compounds?
a. glyceraldehyde-3-phosphate
b. acetyl CoA
c. glucose 6-phosphate
d. lactate
glyceraldehyde 3 phosphate
Which of the following cofactors is required for transketolase activity?
a. biotin
b. thiamine diphosphate
c. pyridoxal phosphate
d. NAD+
thiamine diphosphate
A family presents for genetic counseling. The couple has 2 female children who
are alive and well; however, their infant son recently died in the nursery with
severe hemolysis and jaundice. The wife recalls she lost a brother in infancy with
severe hemolysis. The physician suspects a glucose-6-phosphate
