ATI The Neurological System (Part 1)
A HCP is caring for a patient who is about to begin taking pramipexole (mirapex)
to treat Parkinson's disease. The HCP should recognize that which of the
following laboratory tests require monitoring?
Creatine phosphokinase (CPK)
CPK is an enzyme found in the heart, brain, and skeletal muscles. Patients taking
pramipexole can develop muscle weakness with a lack of energy, creating a situation
that can be more problematic for patients than their original muscle dysfunction.
Monitoring CPK can alert health care professionals to the possibility of skeletal muscle
damage from the drug.
For which of the following should a health care professional monitor a patient
who is taking donepezil (Aricept) for Alzheimer's disease?
Nausea
The most common adverse effects of donepezil, a cholinesterase inhibitor, are nausea,
vomiting, and diarrhea. Taking the drug with food can help minimize adverse effects.
A HCP is talking to a patient who is newly diagnosed with Parkinson's disease
about how levodopa/carbidopa (Sinemet) will hep control her symptoms. which of
the following mechanisms is the drug effective in treating the disorder?
Increases available dopamine in the brain
Levodopa/carbidopa, a dopaminergic agent, can act by increasing dopamine in the
extrapyramidal center of the brain, reducing involuntary motion.
A HCP is talking to a patient who is about to begin taking valproic acid (Depakote)
for a newly diagnosed seizure disorder. He should tell the patient to watch for
which of the following adverse side effects?
drowsiness, headache, rash
-Patients taking valproic acid should report CNS depressant effects, such as sedation or
drowsiness, because these effects can indicate the need for a reduction in dose.
Rash
-Skin rash is a side effect of valproic acid and other antiepileptic drugs.
Which of the following findings should alert a HCP that a patient is developing a
potentially serious adverse side reaction to interferon beta-1b (Betaseron)?
Fatigue
B/c of the potential for bone marrow suppression and decreased platelet count, patients
should report unexplained bruising, bleeding, or fatigue.
While talking to a patient and his family about taking memantine (Namenda) for
Alzheimer's disease, the HCP should include which of the following instructions?
Notify the health care professional before taking over-the-counter antacids.
Antacids that contain sodium bicarbonate increase urine alkalinity and can decrease
drug excretion, ultimately leading to toxicity.
, While talking to a patient about taking modafinil (Provigil) to treat narcolepsy,
which of the following instructions should the HCP include?
Take the drug in the morning
Modafinil is a non-amphetamine stimulant. Taking it in the morning helps improve
wakefulness for patients who have narcolepsy. Patients taking the drug for shift-work
sleepiness should take it 1 hr before work.
A HCP is caring for a patient who is about to begin taking dantrolene (Dantrium)
for skeletal muscle spasms. The HCP should tell the patient to report which of the
following adverse effects?
Diarrhea
Prolonged diarrhea can cause dehydration and other serious effects. Diarrhea is an
adverse effect of dantrolene, as are nausea and vomiting. Patients should report these
effects so the health care professional can monitor fluid balance and intervene
accordingly.
Anesthetists often administer midazolam (Versed) during induction of anesthesia
b/c of which of the following pharmacological actions?
Causes amnesia
Midazolam, a benzodiazepine, is appropriate during induction because of its anti-
anxiety and amnesiac properties.
A HCP is caring for a patient who is about to begin taking dantrolene (Dantrium)
for skeletal muscle spasms. the health care professional should recognize that
which of the following laboratory tests require monitoring?
Liver function
Liver toxicity is a serious adverse effect of dantrolene. The health care professional
should monitor liver function prior to treatment and at regular intervals, and advise
patients to report jaundice or abdominal pain.
A HCP is caring or a patient who is receiving thiopental (Pentothal). For which of
the following should the HCP monitor?
Respiratory depression
Thiopental, a short-acting barbiturate, causes respiratory depression. Mechanical
ventilation and continuous monitoring are essential for patients receiving the drug.
A HCP should include which of the following instruction when talking with a
patient about taking levodopa/carbidopa (Sinemet) to treat Parkinson's disease?
Change position slowly to prevent orthostatic hypotension.
Levodopa/carbidopa can cause orthostatic hypotension
A patient is taking selegiline (Eldepryl) to treat Parkinson's disease. The provider
is considering the use of analgesics for the patient but should be aware that a
drug interaction between selegiline and meperidine (Demerol) can result in which
of the following?
A HCP is caring for a patient who is about to begin taking pramipexole (mirapex)
to treat Parkinson's disease. The HCP should recognize that which of the
following laboratory tests require monitoring?
Creatine phosphokinase (CPK)
CPK is an enzyme found in the heart, brain, and skeletal muscles. Patients taking
pramipexole can develop muscle weakness with a lack of energy, creating a situation
that can be more problematic for patients than their original muscle dysfunction.
Monitoring CPK can alert health care professionals to the possibility of skeletal muscle
damage from the drug.
For which of the following should a health care professional monitor a patient
who is taking donepezil (Aricept) for Alzheimer's disease?
Nausea
The most common adverse effects of donepezil, a cholinesterase inhibitor, are nausea,
vomiting, and diarrhea. Taking the drug with food can help minimize adverse effects.
A HCP is talking to a patient who is newly diagnosed with Parkinson's disease
about how levodopa/carbidopa (Sinemet) will hep control her symptoms. which of
the following mechanisms is the drug effective in treating the disorder?
Increases available dopamine in the brain
Levodopa/carbidopa, a dopaminergic agent, can act by increasing dopamine in the
extrapyramidal center of the brain, reducing involuntary motion.
A HCP is talking to a patient who is about to begin taking valproic acid (Depakote)
for a newly diagnosed seizure disorder. He should tell the patient to watch for
which of the following adverse side effects?
drowsiness, headache, rash
-Patients taking valproic acid should report CNS depressant effects, such as sedation or
drowsiness, because these effects can indicate the need for a reduction in dose.
Rash
-Skin rash is a side effect of valproic acid and other antiepileptic drugs.
Which of the following findings should alert a HCP that a patient is developing a
potentially serious adverse side reaction to interferon beta-1b (Betaseron)?
Fatigue
B/c of the potential for bone marrow suppression and decreased platelet count, patients
should report unexplained bruising, bleeding, or fatigue.
While talking to a patient and his family about taking memantine (Namenda) for
Alzheimer's disease, the HCP should include which of the following instructions?
Notify the health care professional before taking over-the-counter antacids.
Antacids that contain sodium bicarbonate increase urine alkalinity and can decrease
drug excretion, ultimately leading to toxicity.
, While talking to a patient about taking modafinil (Provigil) to treat narcolepsy,
which of the following instructions should the HCP include?
Take the drug in the morning
Modafinil is a non-amphetamine stimulant. Taking it in the morning helps improve
wakefulness for patients who have narcolepsy. Patients taking the drug for shift-work
sleepiness should take it 1 hr before work.
A HCP is caring for a patient who is about to begin taking dantrolene (Dantrium)
for skeletal muscle spasms. The HCP should tell the patient to report which of the
following adverse effects?
Diarrhea
Prolonged diarrhea can cause dehydration and other serious effects. Diarrhea is an
adverse effect of dantrolene, as are nausea and vomiting. Patients should report these
effects so the health care professional can monitor fluid balance and intervene
accordingly.
Anesthetists often administer midazolam (Versed) during induction of anesthesia
b/c of which of the following pharmacological actions?
Causes amnesia
Midazolam, a benzodiazepine, is appropriate during induction because of its anti-
anxiety and amnesiac properties.
A HCP is caring for a patient who is about to begin taking dantrolene (Dantrium)
for skeletal muscle spasms. the health care professional should recognize that
which of the following laboratory tests require monitoring?
Liver function
Liver toxicity is a serious adverse effect of dantrolene. The health care professional
should monitor liver function prior to treatment and at regular intervals, and advise
patients to report jaundice or abdominal pain.
A HCP is caring or a patient who is receiving thiopental (Pentothal). For which of
the following should the HCP monitor?
Respiratory depression
Thiopental, a short-acting barbiturate, causes respiratory depression. Mechanical
ventilation and continuous monitoring are essential for patients receiving the drug.
A HCP should include which of the following instruction when talking with a
patient about taking levodopa/carbidopa (Sinemet) to treat Parkinson's disease?
Change position slowly to prevent orthostatic hypotension.
Levodopa/carbidopa can cause orthostatic hypotension
A patient is taking selegiline (Eldepryl) to treat Parkinson's disease. The provider
is considering the use of analgesics for the patient but should be aware that a
drug interaction between selegiline and meperidine (Demerol) can result in which
of the following?
