Chapter 43, Male and Female Hormones TEST BANK INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION By Susan M Ford

1. An 80-year-old male client with chronic renal insufficiency is prescribed anabolic steroid therapy for the management of anemia associated with renal insufficiency. The nurse will carefully monitor the client for which potential disorder? A) Hypoglycemic attacks B) Serious cardiac disease C) Hypotensive shock D) Cancer of the prostate Answer: D Rationale: Elderly male clients undergoing anabolic steroid therapy are at an increased risk of developing cancer of the prostate gland. Therefore, anabolic steroid therapy needs to be administered cautiously in these clients. Hypoglycemic attacks, serious cardiac disease, and hypotensive shock are not seen in elderly clients on anabolic steroid therapy. Individuals with diabetes have an increased risk of developing hypoglycemia with the use of sulfonylureas and anabolic steroids if also given male hormones. Male hormones are contraindicated in clients with serious cardiac disease. Hypotensive shock can occur with the use of glucocorticoids. Question format: Multiple Choice Chapter: 43 Learning Objective: 1 Cognitive Level: Apply Client Needs: Physiological Integrity: Pharmacological Therapies Integrated Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 577, Anabolic Steroids 2. A nurse is caring for a client with advanced breast cancer who is receiving androgen therapy. Which signs might alert the nurse to the possibility of liver toxicity? A) Edema of the feet B) Increase in appetite C) Clinical jaundice D) Increase in weight Answer: C Rationale: Liver toxicity is indicated by the presence of jaundice. Edema of the feet and an increase in weight may be seen because of fluid and electrolyte imbalance but does not indicate liver toxicity. An increase in appetite shows that the client is responding well to the drug and is not a sign of liver toxicity. Question format: Multiple Choice