BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, AUTONOMIC NERVOUS (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
ANS (INTRODUCTION)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. Regarding adrenergic receptors:
A) Beta-1 is ion-channel-coupled C) Yohimbine is alpha-2 agonist
B) Alpha-1 is Gq protein coupled D) Butoxamine is beta-2 agonist
2. Phenylephrine is a selective agonist for which of the following receptor type?
A) beta-1 C) beta-2
B) alpha-1 D) alpha-2
3. Activation of beta-2 adrenoceptor results in:
A) Glycogenesis C) Vasodilatation
B) Inhibition of insulin release D) Vasoconstriction
4. Which of the following statements is true regarding beta-2 adrenoceptor?
A) Selectively blocked by propranolol.
B) Selectively blocked by salbutamol.
C) Extracellular, coupled to Gs protein.
D) Intracellular, coupled to Gq protein.
5. Which one of the following is a selective beta-1 adrenergic receptor agonist?
A) Atenolol C) Noradrenaline
B) Dobutamine D) Prazosin
6. Which one of the following is an indirect-acting sympathomimetic?
A) Amphetamine C) Ephedrine
B) Isoprenaline D) Procaine
7. Which of the following statements is true regarding Prazosin?
A) alpha-1 receptor agonist C) alpha-2 receptor agonist
B) alpha-1 receptor antagonist D) alpha-2 receptor antagonist
8. Which of the following statements is true regarding Atenolol?
A) Lipophobic beta-1 selective antagonist C) Lipophobic beta2-selective antagonist
B) Lipophilic beta-1 selective antagonist D) Lipophilic beta2-selective antagonist
AUTONOMIC Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
9. Amphetamine is a sympathomimetic drug acting …………………….….:
A) Indirectly via inhibiting uptake-1 of NA?
B) Indirectly via enhancing release of NA?
C) Directly via stimulation of alpha-1 adrenergic receptor?
D) Directly via inhibiting alpha-1 adrenergic receptor?
10. Which one of the following is a selective alpha-2 adrenergic receptor agonist?
A) Atenolol C) Noradrenaline
B) Clonidine D) Prazosin
11. Which one of the following is a dual-acting sympathomimetic?
A) Amphetamine C) Ephedrine
B) Entacapone D) Cocaine
12. Which of the following statements is true regarding Phenylephrine?
A) alpha-1 receptor agonist C) alpha-2 receptor agonist
B) alpha-1 receptor antagonist D) alpha-2 receptor antagonist
13. Which of the following statements is true regarding Propranolol?
A) beta-1 selective agonist C) beta2-selective antagonist
B) beta-1 selective antagonist D) beta-nonselective antagonist
14. Which one of the following drugs can inhibit neuronal uptake of NE?
A) Homatropine C) Procaine
B) Reserpine D) Cocaine
15. Which of the following statements is correct for alpha-1 adrenergic receptor?
A) Ion-channel-coupled C) Gs protein-coupled
B) Phenylephrine is a selective agonist D) Its activation produces profuse salivation
16. Which one of the following is an indirect-acting sympathomimetic?
A) Phenelzine C) Guanethidine
B) Norepinephrine D) Procaine
17. Which one of the following statements is true regarding beta-1 adrenoceptor?
A) Activated by Atenolol C) Gs protein-coupled
B) Blocked by Salbutamol D) Its activation produces bradycardia
18. Which one of the following is an indirect-acting sympathomimetic?
A) Reboxetine C) Isoprenaline
B) Norepinephrine D) Procaine
[End of questions; Total points = 18]
AUTONOMIC Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, AUTONOMIC NERVOUS (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
ANS (ADRENOMIMETICS)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. All the following pharmacological features are true for Epinephrine, except?
A) Non-selective agonist for all adrenergic receptors.
B) Passes blood brain barrier producing marked central effects.
C) Ineffective orally and thus given only by injection.
D) Produces active mydriasis via activation of alpha-1 receptor on Dilator pupillae muscle.
2. All the following actions could be produced by Adrenaline, except?
A) Hypertension
B) Passive mydriasis
C) Vasoconstriction
D) Bronchodilatation
3. Amphetamine is a sympathomimetic drug acting …………………….….:
A) Indirectly via inhibiting uptake-1 of NA?
B) Indirectly via enhancing release of NA?
C) Directly via stimulation of alpha-1 adrenergic receptor?
D) Directly via inhibiting alpha-1 adrenergic receptor?
4. Which of the following actions is not produced by NE?
A) Hypertension
B) Passive mydriasis
C) Vasoconstriction
D) Bronchodilatation
5. Which of the following statements is a correct difference between ephedrine & epinephrine?
A) Epinephrine is effective orally
B) Ephedrine is effective orally
C) Epinephrine has longer duration
D) All of the above
6. Regarding sympathetic drugs, which of the following statements is a correct?
A) Amphetamine acts directly
B) Epinephrine is a non-catecholamine
C) Phenelzine is a MAO inhibitor
D) Both A & B may apply
AUTONOMIC Pharmacology Surviving Revision
PHARMACOLOGY, AUTONOMIC NERVOUS (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
ANS (INTRODUCTION)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. Regarding adrenergic receptors:
A) Beta-1 is ion-channel-coupled C) Yohimbine is alpha-2 agonist
B) Alpha-1 is Gq protein coupled D) Butoxamine is beta-2 agonist
2. Phenylephrine is a selective agonist for which of the following receptor type?
A) beta-1 C) beta-2
B) alpha-1 D) alpha-2
3. Activation of beta-2 adrenoceptor results in:
A) Glycogenesis C) Vasodilatation
B) Inhibition of insulin release D) Vasoconstriction
4. Which of the following statements is true regarding beta-2 adrenoceptor?
A) Selectively blocked by propranolol.
B) Selectively blocked by salbutamol.
C) Extracellular, coupled to Gs protein.
D) Intracellular, coupled to Gq protein.
5. Which one of the following is a selective beta-1 adrenergic receptor agonist?
A) Atenolol C) Noradrenaline
B) Dobutamine D) Prazosin
6. Which one of the following is an indirect-acting sympathomimetic?
A) Amphetamine C) Ephedrine
B) Isoprenaline D) Procaine
7. Which of the following statements is true regarding Prazosin?
A) alpha-1 receptor agonist C) alpha-2 receptor agonist
B) alpha-1 receptor antagonist D) alpha-2 receptor antagonist
8. Which of the following statements is true regarding Atenolol?
A) Lipophobic beta-1 selective antagonist C) Lipophobic beta2-selective antagonist
B) Lipophilic beta-1 selective antagonist D) Lipophilic beta2-selective antagonist
AUTONOMIC Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
9. Amphetamine is a sympathomimetic drug acting …………………….….:
A) Indirectly via inhibiting uptake-1 of NA?
B) Indirectly via enhancing release of NA?
C) Directly via stimulation of alpha-1 adrenergic receptor?
D) Directly via inhibiting alpha-1 adrenergic receptor?
10. Which one of the following is a selective alpha-2 adrenergic receptor agonist?
A) Atenolol C) Noradrenaline
B) Clonidine D) Prazosin
11. Which one of the following is a dual-acting sympathomimetic?
A) Amphetamine C) Ephedrine
B) Entacapone D) Cocaine
12. Which of the following statements is true regarding Phenylephrine?
A) alpha-1 receptor agonist C) alpha-2 receptor agonist
B) alpha-1 receptor antagonist D) alpha-2 receptor antagonist
13. Which of the following statements is true regarding Propranolol?
A) beta-1 selective agonist C) beta2-selective antagonist
B) beta-1 selective antagonist D) beta-nonselective antagonist
14. Which one of the following drugs can inhibit neuronal uptake of NE?
A) Homatropine C) Procaine
B) Reserpine D) Cocaine
15. Which of the following statements is correct for alpha-1 adrenergic receptor?
A) Ion-channel-coupled C) Gs protein-coupled
B) Phenylephrine is a selective agonist D) Its activation produces profuse salivation
16. Which one of the following is an indirect-acting sympathomimetic?
A) Phenelzine C) Guanethidine
B) Norepinephrine D) Procaine
17. Which one of the following statements is true regarding beta-1 adrenoceptor?
A) Activated by Atenolol C) Gs protein-coupled
B) Blocked by Salbutamol D) Its activation produces bradycardia
18. Which one of the following is an indirect-acting sympathomimetic?
A) Reboxetine C) Isoprenaline
B) Norepinephrine D) Procaine
[End of questions; Total points = 18]
AUTONOMIC Pharmacology Surviving Revision
, BENHA UNIVERSITY, CREDIT HOURS SYSTEM
PHARMACOLOGY, AUTONOMIC NERVOUS (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
ANS (ADRENOMIMETICS)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. All the following pharmacological features are true for Epinephrine, except?
A) Non-selective agonist for all adrenergic receptors.
B) Passes blood brain barrier producing marked central effects.
C) Ineffective orally and thus given only by injection.
D) Produces active mydriasis via activation of alpha-1 receptor on Dilator pupillae muscle.
2. All the following actions could be produced by Adrenaline, except?
A) Hypertension
B) Passive mydriasis
C) Vasoconstriction
D) Bronchodilatation
3. Amphetamine is a sympathomimetic drug acting …………………….….:
A) Indirectly via inhibiting uptake-1 of NA?
B) Indirectly via enhancing release of NA?
C) Directly via stimulation of alpha-1 adrenergic receptor?
D) Directly via inhibiting alpha-1 adrenergic receptor?
4. Which of the following actions is not produced by NE?
A) Hypertension
B) Passive mydriasis
C) Vasoconstriction
D) Bronchodilatation
5. Which of the following statements is a correct difference between ephedrine & epinephrine?
A) Epinephrine is effective orally
B) Ephedrine is effective orally
C) Epinephrine has longer duration
D) All of the above
6. Regarding sympathetic drugs, which of the following statements is a correct?
A) Amphetamine acts directly
B) Epinephrine is a non-catecholamine
C) Phenelzine is a MAO inhibitor
D) Both A & B may apply
AUTONOMIC Pharmacology Surviving Revision
