2024 LATEST Hematology AAB MT

Mean corpuscular hemoglobin (MCH) - ANSWER Average mass of hemoglobin per red blood cell in a sample of blood. Mean corpuscular hemoglobin concentration (MCHC) - ANSWER Measure of the concentration of hemoglobin in a given volume of packed red blood cells Red blood cell distribution width (RDW) - ANSWER A measure of the variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count Best Romanowsky stain modification for demonstrating of blood parasites - ANSWER Giemsa stain Prussian Blue - ANSWER Stain for iron Myeloblasts with granules and eosinophils stain positive - ANSWER Sudan Black B stain True or false, peroxidase activity is present in all stages of neutrophils? - ANSWER True Enzyme present only in maturing neutrophils from metamyelocyte forward - ANSWER Leukocyte alkaline phosphatase (LAP) Does not inhibit acid phosphatase in hairy cell leukemia - ANSWER L (+) tartic acid Put the following terms in order of RBC maturation: Rubricyte,RBC, Metarubricyte,Prorubricyte, Rubriblast - ANSWER Rubriblast, prorubricyte, rubricyte, metarubricyte, RBC Which is the last nucleated RBC cell capable of cell division? - ANSWER Rubricyte What is a moderate enlargement of the spleen indicative of? - ANSWER Chronic liver disease What is a mild enlargement of the spleen indicative of? - ANSWER Fe deficiency anemia and hemolytic anemia What type of anemia has the following description: macrocytic, vit B12 deficiency, and lack of RBC - ANSWER Megaloblastic anemia Lipemic, icteric, or agglutinated specimens when run on automated hematology analyzers - ANSWER Increase MCHC RDW is diagnosticaaly helpful in disease when correlated with what other parameter? - ANSWER MCV What is a reliable indicator of rate erythropoiesis? - ANSWER RPI- reticulocyte production index Bronze elliptocyte - ANSWER Most typical finding in sickle cell anemia Red cell shape- In vivo-neonatal liver disease, McLeod pheno-type (Kx) - ANSWER Crenated cell Red cell shape- microangiopathic hemolytic anemia (DIC, TTP,HUS) - ANSWER Schistocytes Macroovalocyte - ANSWER Deficiency of B12 folate Acanthocyte (spur cell) - ANSWER Alcoholic cirrhosis What red cell shape is indicative of Rh null syndrome? - ANSWER Stomatocyte Lepocyte (target cell) - ANSWER Hb-C, Hb-E disease, thalassemias, liver disease, postsplenectomy Cabot ring - ANSWER DNA remnant Heinz bodies - ANSWER Ppt Hb or G6PD deficiency DNA (aberrant chromosomes)-presence usually signifies a damaged spleen - ANSWER Howell-Jolly Bodies Flat blue-gray pieces-nonheme Fe - ANSWER Pappenheimer bodies Sideroblastic anemia - ANSWER Disease in which the bone marrow produces ringed sideroblasts; the body has iron available but cannot incorporate it into hemoglobin; granules of iron accumulated in perinuclear mitochondria Most easily confused with IDA on peripheral smear but not an iron deficiency - ANSWER Thalassemia minor High serum iron, normal TIBC, low Hb,Common in Mediterranean area - ANSWER Beta thalassemia Thalassemia - ANSWER an inherited form of anemia caused by faulty synthesis of hemoglobin Massive splenomegaly, severe HA, greatly increased Hb-F - ANSWER Beta-Beta=Thal major