Liver Function Test
Introduction :
Biochemical tests for diagnosis &
monitoring of liver diseases
°
are
referred as liver
function tests ( LET) -
Tests
classified functions of liver
•
were on
major :
Excretion bile salts
pigments
la '
g . bromsulpthalein ,
bile etc
b , Metabolism
(
of carbohydrates and A- As -
(c)
Synthesis of proteins serum
( d,
Detoxification of Ammonia &
flippant acid synthesis
Serum
(e)
enzymes (
as
markers )
•
But
nowadays ,
( Fts are
broadly classified as :
in Tests to detect hepatic injury :
ca ) whether mild / severe
,
acute or chronic .
(b) Nature cholestasis
g
injury -
hepatocellular or .
(2) Tests to assess
hepatic function .
Functions of liver :
(I ,
synthetic functions
Metabolic
(21
functions
13 , Detoxification
( 41 Excretion
(5) Homeostasis
(6 ,
storage
its Production g Bile salts
is ,
Help in
digestion og fat
.
Emulsification )
, Function
Classification of
liver Tests :
[A ] Based on
laboratory findings :
based liver
(a)
GI ( tests on
Excretory Function ) :
Bilirubin der
cis Semen : Van
Bergh Klan
(2) Serum Bilirubin : Ict eric Index
(3) Urine bilirubin and Bile salts
(4) Urine
urobilinogen fecal stercobilinogen
&
ambition
fecal stereo bilin
(5) Urine & -
b, tests biomarkers
( Groupie ( liver
enzyme panel
:
for liver
injury
and chol esta sis )
Alkaline
( 11
phosphatase ( ALP )
( 21 Serum
glutamate pyruvate transaminase ( SG PT ) / ALT
(3) Serum
glutamate oxalate transaminase ( 5907 ) IAST
4 Gamma
( ,
Glutamyl Transferase ( GGT )
isocitrate
is , Senen
dehydrogenase
(6) Choline esterase
(F) 5' nucleotidase .
(C '
Gnup ( Tests for synthetic function g
liver ) ( Plasma Proteins )
in Total
proteins
albumin
(2) Serum
g
globulin . Ala Ratio
(3) Prothrombin time
( Gi flocculation test .
(5) A- As in blood & Urine .
concentration
61
Fibrinogen .
Introduction :
Biochemical tests for diagnosis &
monitoring of liver diseases
°
are
referred as liver
function tests ( LET) -
Tests
classified functions of liver
•
were on
major :
Excretion bile salts
pigments
la '
g . bromsulpthalein ,
bile etc
b , Metabolism
(
of carbohydrates and A- As -
(c)
Synthesis of proteins serum
( d,
Detoxification of Ammonia &
flippant acid synthesis
Serum
(e)
enzymes (
as
markers )
•
But
nowadays ,
( Fts are
broadly classified as :
in Tests to detect hepatic injury :
ca ) whether mild / severe
,
acute or chronic .
(b) Nature cholestasis
g
injury -
hepatocellular or .
(2) Tests to assess
hepatic function .
Functions of liver :
(I ,
synthetic functions
Metabolic
(21
functions
13 , Detoxification
( 41 Excretion
(5) Homeostasis
(6 ,
storage
its Production g Bile salts
is ,
Help in
digestion og fat
.
Emulsification )
, Function
Classification of
liver Tests :
[A ] Based on
laboratory findings :
based liver
(a)
GI ( tests on
Excretory Function ) :
Bilirubin der
cis Semen : Van
Bergh Klan
(2) Serum Bilirubin : Ict eric Index
(3) Urine bilirubin and Bile salts
(4) Urine
urobilinogen fecal stercobilinogen
&
ambition
fecal stereo bilin
(5) Urine & -
b, tests biomarkers
( Groupie ( liver
enzyme panel
:
for liver
injury
and chol esta sis )
Alkaline
( 11
phosphatase ( ALP )
( 21 Serum
glutamate pyruvate transaminase ( SG PT ) / ALT
(3) Serum
glutamate oxalate transaminase ( 5907 ) IAST
4 Gamma
( ,
Glutamyl Transferase ( GGT )
isocitrate
is , Senen
dehydrogenase
(6) Choline esterase
(F) 5' nucleotidase .
(C '
Gnup ( Tests for synthetic function g
liver ) ( Plasma Proteins )
in Total
proteins
albumin
(2) Serum
g
globulin . Ala Ratio
(3) Prothrombin time
( Gi flocculation test .
(5) A- As in blood & Urine .
concentration
61
Fibrinogen .
