PHARMACOLOGY, CARDIOVASCULAR SYSTEM (PHA311)
FOR STUDENTS ENROLLED IN PHARMACOLOGY PROGRAMS
CARDIOVASCULAR DRUGS (Cardiac Stimulants/Depressants)
MCQs
Notes:
(i) Each Question has 4 points to choose from. Choose ONLY ONE point to answer the Question.
(ii) Answer the questions after carefully reading the text.
1. The term “Cardiac stimulant” refers to:
A) A drug which increases rate of heart beats.
B) A drug which increases force of heart beats.
C) A drug which increases both A & B.
D) None the above.
2. The term “Cardiac depressant” refers to a drug which decreases rate and depth of heart beating.
A) True.
B) False.
3. The term “Cardiac tonic” refers to:
A) A drug which increases rate of heart beats.
B) A drug which increases force of heart beats.
C) A drug which increases force but decreases rate of heart beats.
D) None the above.
4. The term Cardiac tonic differs from the tern Cardiac stimulant.
A) True.
B) False.
5. Adrenaline acts as a cardiac stimulant by:
A) stimulating cardiac beta-1 adrenoceptor.
B) blocking M2-cholinoceptor on cardiac muscle.
C) directly stimulating cardiac myocyte membrane.
D) stimulating vasomotor center in the medulla oblongata.
6. Adrenaline injection does not stimulate vasomotor center as it cannot pass BBB.
A) True
B) False
7. Camphor, after subcutaneous injection, acts as a cardiac stimulant by:
A) stimulating cardiac beta-1 adrenoceptor.
B) blocking M2-cholinoceptor on cardiac muscle.
C) reflexly stimulating cardiac myocytes.
D) reflexly stimulating vasomotor center in the medulla oblongata.
8. Ammonia, when given by inhalation or orally, stimulate vasomotor center directly.
A) True
B) False
Cardiovascular system Pharmacology Surviving Revision
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9. Theophylline acts as a cardiac stimulant by:
A) directly stimulating cardiac myocyte membrane.
B) directly stimulating vasomotor center in the medulla oblongata.
C) stimulating cardiac beta-1 adrenoceptor.
D) Both A & B may apply.
10. Cardiac stimulants are indicated therapeutically in:
A) Tachycardia and atrial flutter.
B) During and after general anaesthesia.
C) Cardiac depression.
D) Both B & C may apply.
11. Atropine, acts as a cardiac stimulant by:
A) stimulating cardiac beta-1 adrenoceptor.
B) blocking M2-cholinoceptor on cardiac muscle.
C) reflexly stimulating cardiac myocytes.
D) reflexly stimulating vasomotor center in the medulla oblongata.
12. Gallamine, acts as a cardiac stimulant by:
A) stimulating cardiac beta-1 adrenoceptor.
B) blocking M2-cholinoceptor on cardiac muscle.
C) reflexly stimulating cardiac myocytes.
D) reflexly stimulating vasomotor center in the medulla oblongata.
13. Hyoscine stimulates cardiac muscle but depresses vasomotor center unlike atropine which stimulates cardiac
muscle and vasomotor center as well.
A) True
B) False
14. Xanthine alkaloids stimulate cardiac muscle both centrally and peripherally.
A) True
B) False
15. Dobutamine is a selective cardiac stimulant unlike Adrenaline that is nonselective.
A) True
B) False
[End of questions; Total points = 15]
Cardiovascular system Pharmacology Surviving Revision