Reproductive System Pharmacology Course Notes - Easy Simple Concise Understood

Drugs affecting the Reproductive System
Classification
Drugs acting on the reproductive system are classified acc. to
their nature of action into the following groups:

Gonadotropins

Sex hormones

Drugs affecting the uterus

Cervical dilators

Drugs affecting the sexual desire

, I- GONADOTROPINS
Members:
1- Pituitary gonadotropins:
FSH (Follicle Stimulating Hormone)

LH (Luteinizing Hormone)


2- Non-Pituitary gonadotropins:
PMS (Pregnant mare serum)

HCG (Human chorionic gonadotropin)

, PITUITARY GONADOTROPINS
Members:
FSH (Follicle Stimulating H.) & LH (Luteinizing H.)

Release control:
Under the effects of hypothalamic gonadotropin-RHs.
Follicle Stimulating hormone-releasing hormone (FSH-RH)
Luteinizing hormone-releasing hormone (LH-RH)

Actions:
- ↑ vascularity & thus activity of gonads,
leading to:

, PITUITARY GONADOTROPINS 2/3
FSH LH

Development of ovarian Maturation of ovarian
follicles ( ). follicles ( )
Spermatogenesis ( ). Ovulation ( )

Maintenance of CL &
synthesis and release of
progesterone ( )

Synthesis & release of Synthesis & release of
estradiol ( ). testosterone ( )

Puberty ( ). Puberty ( )